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Article
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gene targeting
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genetics
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human
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controlled study
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metabolism
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gene expression regulation
17
female
15
gene expression
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human cell
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adult
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male
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unclassified drug
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human tissue
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down regulation
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real time polymerase chain reaction
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upregulation
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Female
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MicroRNAs
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gene function
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major clinical study
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microRNA
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middle aged
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Gene Expression Regulation, Neoplastic
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Male
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nonhuman
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pathology
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Cell Line, Tumor
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Middle Aged
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621“... of MCD. Some new technologies, such as gene targeting therapy and enzyme replacement therapy, are also...”
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622“... of the AREs present within the Bcl2 3'UTR in order to maintain Bcl2 expression. Gene targeting deletion of 300...”
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623“... diseases. Recent in vivo research using gene-targeting mouse models have advanced our knowledge about...”
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624by Fu, Qiang“... function of IGFBP-3, gene targeting technique was employed to generate a null IGFBP-3 mouse model...”
Published 2007
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625by Ino Mitsuhiro, Miyamoto Norimasa, Takahashi Eiki, Hirohashi Tomoko, Kai Junko, Hayakawa Kazuhiro, Sagane Koji, Oki Tohru, Yamazaki Kazuto, Nagasu Takeshi“... the physiological functions of ADAM22, we employed gene targeting to generate ADAM22 knockout mice.</p> <p>Results...”
Published 2005-05-01
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626“..., and gene targeting therapy for malignant tumors has achieved preliminary progress. As one of the first...”
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627by Maíra P Martins, Eriston V Gomes, Pablo R Sanches, Wellington R Pedersoli, Nilce M Martinez-Rossi, Antonio Rossi“... genes KU70, KU80, and LIG4, respectively, provides efficient tools for gene targeting. Accordingly, we...”
Published 2018-01-01
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628“... methods and the construction of animal models using gene targeting in mice. Recent data suggest that BRCA2...”
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629by Yuh-Man Sun, Megan Cooper, Sophie Finch, Hsuan-Hwai Lin, Zhou-Feng Chen, Brenda P Williams, Noel J Buckley“... embryonic stem (ES) cells and an early abrogation of Rest in ES cells using a combination of gene targeting...”
Published 2008-01-01
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630“... or synergistic multi-gene targeting are surely decisive, while caution must be exerted to avoid potential toxic...”
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631“... be delicate control of gene regulation during Tex4 expression. Furthermore, gene targeting and gene knockdown...”
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632by Wu, Di“... of the postnatal retina. Next, to address function, I used a conditional gene targeting approach to show...”
Published 2017
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633“..., such as proteins and RNAs to interacting organisms. Recent studies revealed that plant EVs deliver fungal gene...”
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634“... phosphorylase 4a (pnp4a). Gene targeting and complementation testing showed that pnp4a is the causal gene of gu...”
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636“... of NC-derived cells in vitro. Moreover, the strategy of gene targeting in mouse has led at identifying...”
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637by Funk, Natalja“... to a novel protein family of unknown function. Three techniques were used for Sap47 mutagenesis: "gene...”
Published 2003
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638“... editing. Compared to traditional gene-targeting strategies, CRISPR-Cas9 technology offers a more efficient...”
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639by Viviana Barra, Glennis A. Logsdon, Andrea Scelfo, Sebastian Hoffmann, Solène Hervé, Aaron Aslanian, Yael Nechemia-Arbely, Don W. Cleveland, Ben E. Black, Daniele Fachinetti“.... Here, the authors use gene targeting at both endogenous CENP-A alleles and gene replacement in human...”
Published 2019-01-01
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640by Jintan Liu, Sanjana Srinivasan, Chieh-Yuan Li, I-Lin Ho, Johnathon Rose, MennatAllah Shaheen, Gang Wang, Wantong Yao, Angela Deem, Chris Bristow, Traver Hart, Giulio Draetta“... demonstrate functional genomic screens with AsCpf1 that minimize library size with no loss in gene targeting...”
Published 2019-07-01
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