Altered Synapse Stability in the Early Stages of Tauopathy

by Johanna S. Jackson, Jonathan Witton, James D. Johnson, Zeshan Ahmed, Mark Ward, Andrew D. Randall, Michael L. Hutton, John T. Isaac, Michael J. O’Neill, Michael C. Ashby
Published 2017-03-01

Targeting the Synapse in Alzheimer’s Disease

by Johanna Jackson, Enrique Jambrina, Jennifer Li, Hugh Marston, Fiona Menzies, Keith Phillips, Gary Gilmour
Published 2019-07-01

Coordinated Acetylcholine Release in Prefrontal Cortex and Hippocampus Is Associated with Arousal and Reward on Distinct Timescales

by Leonor M. Teles-Grilo Ruivo, Keeley L. Baker, Michael W. Conway, Peter J. Kinsley, Gary Gilmour, Keith G. Phillips, John T.R. Isaac, John P. Lowry, Jack R. Mellor
Published 2017-01-01

Transcriptional Signatures of Tau and Amyloid Neuropathology

by Isabel Castanho, Tracey K. Murray, Eilis Hannon, Aaron Jeffries, Emma Walker, Emma Laing, Hedley Baulf, Joshua Harvey, Lauren Bradshaw, Andrew Randall, Karen Moore, Paul O’Neill, Katie Lunnon, David A. Collier, Zeshan Ahmed, Michael J. O’Neill, Jonathan Mill
Published 2020-02-01

Orexin A induced increases in rat locus coeruleus neuronal activity are attenuated by systemic administration of OX1R and OX2R antagonists

by Christopher M. Holton, Gary Gilmour, Keith A. Wafford
Published 2020-09-01

TRPV3 in Drug Development

by Lisa M. Broad, Adrian J. Mogg, Elizabeth Eberle, Marcia Tolley, Dominic L. Li, Kelly L. Knopp
Published 2016-09-01

GABA𝐀 Receptor Subtypes: Novel Targets for Novel Medicines

by Naheed R. Mirza, John Atack, Keith Wafford
Published 2012-01-01

In Vivo Imaging of Tau Pathology Using Magnetic Resonance Imaging Textural Analysis

by Niall Colgan, Niall Colgan, Balaji Ganeshan, Ian F. Harrison, Ozama Ismail, Holly E. Holmes, Jack A. Wells, Nick M. Powell, James M. O'Callaghan, Michael J. O'Neill, Tracey K. Murray, Zeshan Ahmed, Emily C. Collins, Ross A. Johnson, Ashley Groves, Mark F. Lythgoe
Published 2017-11-01

Cost-effectiveness analysis of ixekizumab versus secukinumab in patients with psoriatic arthritis and concomitant moderate-to-severe psoriasis in Spain

by Susanne Hartz, Christophe Sapin, Bernd Schweikert, Chiara Malmberg, Mercedes Núñez, Tatiana Dilla
Published 2020-08-01

Pharmacokinetics of doxorubicin following concomitant intravenous administration of olaratumab (IMC‐3G3) to patients with advanced soft tissue sarcoma

by Victor M. Villalobos, Gary Mo, Mark Agulnik, Seth M. Pollack, Daniel A. Rushing, Arun Singh, Brian A. Van Tine, Rhian McNaughton, Rodney L. Decker, Wei Zhang, Ashwin Shahir, Damien M. Cronier
Published 2020-02-01

Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H₂O₂- and Aβ_1-42-Induced Toxicity in SH-SY5Y Hum...

by Ana M. de Matos, Alice Martins, Teresa Man, David Evans, Magnus Walter, Maria Conceição Oliveira, Óscar López, José G. Fernandez-Bolaños, Philipp Dätwyler, Beat Ernst, M. Paula Macedo, Marialessandra Contino, Nicola A. Colabufo, Amélia P. Rauter
Published 2019-06-01

Selective nicotinic acetylcholine receptor subunit deficits identified in Alzheimer's disease, Parkinson's disease and dementia with Lewy bodies by immunoprecipitation

by Cecilia Gotti, Milena Moretti, Iwo Bohr, Iryna Ziabreva, Silvia Vailati, Renato Longhi, Loredana Riganti, Annalisa Gaimarri, Ian G. McKeith, Robert H. Perry, Dag Aarsland, Jan Petter Larsen, Emanuele Sher, Ruth Beattie, Francesco Clementi, Jennifer A. Court
Published 2006-08-01

Synthesis of fused tricyclic amines unsubstituted at the ring-junction positions by a cascade condensation, cyclization, cycloaddition then decarbonylation strategy

by Iain Coldham, Adam J. M. Burrell, Hélène D. S. Guerrand, Luke Watson, Nathaniel G. Martin, Niall Oram
Published 2012-01-01

Long-term safety and efficacy of lasmiditan for acute treatment of migraine: Final results of the GLADIATOR study

by Jan Lewis Brandes, Suzanne Klise, John H Krege, Michael Case, Rashna Khanna, Raghavendra Vasudeva, Joel Raskin, David Kudrow
Published 2020-09-01

Impaired speed encoding and grid cell periodicity in a mouse model of tauopathy

by Thomas Ridler, Jonathan Witton, Keith G Phillips, Andrew D Randall, Jonathan T Brown
Published 2020-11-01

Impact of anxiety symptoms on outcomes of depression: an observational study in Asian patients

by Novick D, Montgomery W, Aguado J, Peng XM, Haro JM
Published 2016-04-01

Recovery in patients with major depressive disorder (MDD): results of a 6-month, multinational, observational study

by Novick D, Montgomery W, Vorstenbosch E, Moneta MV, Dueñas H, Haro JM
Published 2017-10-01

A review of the efficacy of atomoxetine in the treatment of attention-deficit hyperactivity disorder in children and adult patients with common comorbidities

by Clemow DB, Bushe C, Mancini M, Ossipov MH, Upadhyaya H
Published 2017-02-01

Costi del trattamento con oloprazina nelle fasi iniziali della schizofrenia

by Domenico Berardi, Maddalena Dell’Atti, Francesca Russo, Virginia Vagnini, Luca Guidi, Eric T. Edgell
Published 2002-06-01

A 6-year open-label study of the efficacy and safety of olanzapine long-acting injection in patients with schizophrenia: a post hoc analysis based on the European label recommendat...

by An, E, Berggren L, Deix C, Tóth Á, McDonnell DP
Published 2015-05-01