Multi-Gene Prognostic Signatures and Prediction of Pathological Complete Response to Neoadjuvant Chemotherapy in ER-positive, HER2-negative Breast Cancer Patients

by Claudia Mazo, Stephen Barron, Catherine Mooney, William M. Gallagher
Published 2020-05-01

Clinical Decision Support Systems in Breast Cancer: A Systematic Review

by Claudia Mazo, Cathriona Kearns, Catherine Mooney, William M. Gallagher
Published 2020-02-01

The Role of Gut Barrier Dysfunction and Microbiome Dysbiosis in Colorectal Cancer Development

by Flavia Genua, Vedhika Raghunathan, Mazda Jenab, William M. Gallagher, David J. Hughes
Published 2021-04-01

High-throughput proteomics detection of novel splice isoforms in human platelets.

by Karen A Power, James P McRedmond, Andreas de Stefani, William M Gallagher, Peadar O Gaora
Published 2009-01-01

Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer

by Lorraine Burke, Lorraine Burke, Clare T. Butler, Adrian Murphy, Bruce Moran, William M Gallagher, Jacintha O'Sullivan, Breandán N. Kennedy
Published 2016-09-01

A texture based pattern recognition approach to distinguish melanoma from non-melanoma cells in histopathological tissue microarray sections.

by Elton Rexhepaj, Margrét Agnarsdóttir, Julia Bergman, Per-Henrik Edqvist, Michael Bergqvist, Mathias Uhlén, William M Gallagher, Emma Lundberg, Fredrik Ponten
Published 2013-01-01

Inhibition of Serum Response Factor Improves Response to Enzalutamide in Prostate Cancer

by R. William Watson, Haleema Azam, Claudia Aura, Niamh Russell, Janet McCormack, Eva Corey, Colm Morrissey, John Crown, William M Gallagher, Maria Prencipe
Published 2020-11-01

Lysosome triggered near-infrared fluorescence imaging of cellular trafficking processes in real time

by Marco Grossi, Marina Morgunova, Shane Cheung, Dimitri Scholz, Emer Conroy, Marta Terrile, Angela Panarella, Jeremy C. Simpson, William M. Gallagher, Donal F. O’Shea
Published 2016-03-01

Triple Combination of Ascorbate, Menadione and the Inhibition of Peroxiredoxin-1 Produces Synergistic Cytotoxic Effects in Triple-Negative Breast Cancer Cells

by Malgorzata Bajor, Agnieszka Graczyk-Jarzynka, Katsiaryna Marhelava, Malgorzata Kurkowiak, Arman Rahman, Claudia Aura, Niamh Russell, Agata O. Zych, Malgorzata Firczuk, Magdalena Winiarska, William M. Gallagher, Radoslaw Zagozdzon
Published 2020-04-01

Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate...

by Gillian O'Hurley, Christer Busch, Linn Fagerberg, Björn M Hallström, Charlotte Stadler, Anna Tolf, Emma Lundberg, Jochen M Schwenk, Karin Jirström, Anders Bjartell, William M Gallagher, Mathias Uhlén, Fredrik Pontén
Published 2015-01-01

The Molecular Effects of a High Fat Diet on Endometrial Tumour Biology

by Michael Wilkinson, Piriyah Sinclair, Ludmilla Dellatorre-Teixeira, Patrick Swan, Eoin Brennan, Bruce Moran, Dirk Wedekind, Paul Downey, Kieran Sheahan, Emer Conroy, William M. Gallagher, Neil Docherty, Carel le Roux, Donal J. Brennan
Published 2020-09-01

High Cysteinyl Leukotriene Receptor 1 Expression Correlates with Poor Survival of Uveal Melanoma Patients and Cognate Antagonist Drugs Modulate the Growth, Cancer Secretome, and Me...

by Kayleigh Slater, Aisling B. Heeran, Sandra Garcia-Mulero, Helen Kalirai, Rebeca Sanz-Pamplona, Arman Rahman, Nebras Al-Attar, Mays Helmi, Fiona O’Connell, Rosa Bosch, Anna Portela, Alberto Villanueva, William M. Gallagher, Lasse D. Jensen, Josep M. Piulats, Sarah E. Coupland, Jacintha O’Sullivan, Breandán N. Kennedy
Published 2020-10-01

Understanding and Attitudes toward Cancer Clinical Trials among Patients with a Cancer Diagnosis: National Study through Cancer Trials Ireland

by Cathriona Kearns, Ronan Feighery, John Mc Caffrey, Michaela Higgins, Martina Smith, Verena Murphy, Seamus O’Reilly, Anne M. Horgan, Janice Walshe, Ray McDermott, Patrick G. Morris, Maccon Keane, Michael Martin, Conleth Murphy, Karen Duffy, Alina Mihai, John Armstrong, Dearbhaile M. O’Donnell, William M. Gallagher, Ciara M. Kelly, Catherine M. Kelly
Published 2020-07-01

What are the mechanisms that enable the reciprocal involvement of seldom heard groups in health and social care research? A rapid realist review protocol [version 1; peer review: 3...

by Éidín Ní Shé, Carmel Davies, Catherine Blake, Rachel Crowley, Amanda McCann, Brona Fullen, Deirdre O'Donnell, Joan O'Connor, Sheila Kelly, Majella Darcy, Fiona Bolger, Sue Ziebland, Mervyn Taylor, Phillip Watt, Diarmaid O'Sullivan, Mary Day, Derick Mitchell, Sarah Donnelly, Eilish McAuliffe, William M. Gallagher, Judy Walsh, Naonori Kodate, Laura Cutlar, Marie Therese Cooney, Thilo Kroll
Published 2018-02-01

Implementing Systems Modelling and Molecular Imaging to Predict the Efficacy of BCL-2 Inhibition in Colorectal Cancer Patient-Derived Xenograft Models

by Alice C. O’Farrell, Monika A. Jarzabek, Andreas U. Lindner, Steven Carberry, Emer Conroy, Ian S. Miller, Kate Connor, Liam Shiels, Eugenia R. Zanella, Federico Lucantoni, Adam Lafferty, Kieron White, Mariangela Meyer Meyer Villamandos, Patrick Dicker, William M. Gallagher, Simon A. Keek, Sebastian Sanduleanu, Philippe Lambin, Henry C. Woodruff, Andrea Bertotti, Livio Trusolino, Annette T. Byrne, Jochen H.M. Prehn
Published 2020-10-01

Development of acquired resistance to lapatinib may sensitise HER2-positive breast cancer cells to apoptosis induction by obatoclax and TRAIL

by Alex J Eustace, Neil T Conlon, Martina S J McDermott, Brigid C Browne, Patrick O’Leary, Frankie A Holmes, Virginia Espina, Lance A Liotta, Joyce O’Shaughnessy, Clair Gallagher, Lorraine O’Driscoll, Sweta Rani, Stephen F Madden, Neil A O’Brien, Charles Ginther, Dennis Slamon, Naomi Walsh, William M Gallagher, Radoslaw Zagozdzon, William R Watson, Norma O’Donovan, John Crown
Published 2018-10-01

Comprehensive DNA methylation study identifies novel progression-related and prognostic markers for cutaneous melanoma

by Jasper Wouters, Miguel Vizoso, Anna Martinez-Cardus, F. Javier Carmona, Olivier Govaere, Teresa Laguna, Jesuchristopher Joseph, Peter Dynoodt, Claudia Aura, Mona Foth, Roy Cloots, Karin van den Hurk, Balazs Balint, Ian G. Murphy, Enda W. McDermott, Kieran Sheahan, Karin Jirström, Bjorn Nodin, Girish Mallya-Udupi, Joost J. van den Oord, William M. Gallagher, Manel Esteller
Published 2017-06-01

A Novel Positron Emission Tomography (PET) Approach to Monitor Cardiac Metabolic Pathway Remodeling in Response to Sunitinib Malate.

by Alice C O'Farrell, Rhys Evans, Johanna M U Silvola, Ian S Miller, Emer Conroy, Suzanne Hector, Maurice Cary, David W Murray, Monika A Jarzabek, Ashwini Maratha, Marina Alamanou, Girish Mallya Udupi, Liam Shiels, Celine Pallaud, Antti Saraste, Heidi Liljenbäck, Matti Jauhiainen, Vesa Oikonen, Axel Ducret, Paul Cutler, Fionnuala M McAuliffe, Jacques A Rousseau, Roger Lecomte, Suzanne Gascon, Zoltan Arany, Bonnie Ky, Thomas Force, Juhani Knuuti, William M Gallagher, Anne Roivainen, Annette T Byrne
Published 2017-01-01

Pilot study of bevacizumab in combination with docetaxel and cyclophosphamide as adjuvant treatment for patients with early stage HER-2 negative breast cancer, including analysis o...

by Giuseppe Gullo, Alex J. Eustace, Alexandra Canonici, Denis M. Collins, Michael J. Kennedy, Liam Grogan, Oscar Breathhnach, John McCaffrey, Maccon Keane, Michael J. Martin, Rajnish Gupta, Gregory Leonard, Miriam O’Connor, Paula M. Calvert, Paul Donnellan, Janice Walshe, Enda McDermott, Kathleen Scott, Andres Hernando, Imelda Parker, David W. Murray, Alice C. O’Farrell, Ashwini Maratha, Patrick Dicker, Mairin Rafferty, Verena Murphy, Norma O’Donovan, William M. Gallagher, Bonnie Ky, Dimitrios Tryfonopoulos, Brian Moulton, Annette T. Byrne, John Crown
Published 2019-07-01

Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy

by Dominiek Smeets, Ian S. Miller, Darran P. O’Connor, Sudipto Das, Bruce Moran, Bram Boeckx, Timo Gaiser, Johannes Betge, Ana Barat, Rut Klinger, Nicole C. T. van Grieken, Chiara Cremolini, Hans Prenen, Massimiliano Mazzone, Jeroen Depreeuw, Orna Bacon, Bozena Fender, Joseph Brady, Bryan T. Hennessy, Deborah A. McNamara, Elaine Kay, Henk M. Verheul, Neerincx Maarten, William M. Gallagher, Verena Murphy, Jochen H. M. Prehn, Miriam Koopman, Cornelis J. A. Punt, Fotios Loupakis, Matthias P. A. Ebert, Bauke Ylstra, Diether Lambrechts, Annette T. Byrne
Published 2018-10-01