Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids

by Marko Z Nikolić, Oriol Caritg, Quitz Jeng, Jo-Anne Johnson, Dawei Sun, Kate J Howell, Jane L Brady, Usua Laresgoiti, George Allen, Richard Butler, Matthias Zilbauer, Adam Giangreco, Emma L Rawlins
Published 2017-06-01

Evidence for a novel overlapping coding sequence in POLG initiated at a CUG start codon

by Yousuf A. Khan, Irwin Jungreis, James C. Wright, Jonathan M. Mudge, Jyoti S. Choudhary, Andrew E. Firth, Manolis Kellis
Published 2020-03-01

The genome sequence of the Eurasian river otter, Lutra lutra Linnaeus 1758 [version 1; peer review: 2 approved]

by Dan Mead, Frank Hailer, Elisabeth Chadwick, Roberto Portela Miguez, Michelle Smith, Craig Corton, Karen Oliver, Jason Skelton, Emma Betteridge, Jale Doulcan Doulcan, Olga Dudchenko, Arina Omer, David Weisz, Erez Lieberman Aiden, Shane McCarthy, Kerstin Howe, Ying Sims, James Torrance, Alan Tracey, Richard Challis, Richard Durbin, Mark Blaxter
Published 2020-02-01

Population genetic structure and predominance of cyclical parthenogenesis in the bird cherry‐oat aphid Rhopalosiphum padi in England

by Ramiro Morales‐Hojas, Asier Gonzalez‐Uriarte, Fernando Alvira Iraizoz, Todd Jenkins, Lynda Alderson, Tracey Kruger, Mike J. Hall, Alex Greenslade, Chris R. Shortall, James R. Bell
Published 2020-05-01

FGFR1 Oncogenic Activation Reveals an Alternative Cell of Origin of SCLC in Rb1/p53 Mice

by Giustina Ferone, Ji-Ying Song, Oscar Krijgsman, Jan van der Vliet, Miranda Cozijnsen, Ekaterina A. Semenova, David J. Adams, Daniel Peeper, Anton Berns
Published 2020-03-01

Micro-epidemiological structuring of Plasmodium falciparum parasite populations in regions with varying transmission intensities in Africa. [version 1; referees: 2 approved]

by Irene Omedo, Polycarp Mogeni, Teun Bousema, Kirk Rockett, Alfred Amambua-Ngwa, Isabella Oyier, Jennifer C. Stevenson, Amrish Y. Baidjoe, Etienne P. de Villiers, Greg Fegan, Amanda Ross, Christina Hubbart, Anne Jeffreys, Thomas N. Williams, Dominic Kwiatkowski, Philip Bejon
Published 2017-02-01

The future of genomics in Ireland – focus on genomics for health [version 1; peer review: 2 approved]

by Cathal Seoighe, Adrian P. Bracken, Patrick Buckley, Peter Doran, Robert Green, Sandra Healy, David Kavanagh, Elaine Kenny, Mark Lawler, Maeve Lowery, Derek Morris, Darrin Morrissey, James J. O'Byrne, Denis Shields, Owen Smith, Charles A. Steward, Brian Sweeney, Walter Kolch
Published 2020-12-01

Identifying proteins bound to native mitotic ESC chromosomes reveals chromatin repressors are important for compaction

by Dounia Djeghloul, Bhavik Patel, Holger Kramer, Andrew Dimond, Chad Whilding, Karen Brown, Anne-Céline Kohler, Amelie Feytout, Nicolas Veland, James Elliott, Tanmay A. M. Bharat, Abul K. Tarafder, Jan Löwe, Bee L. Ng, Ya Guo, Jacky Guy, Miles K. Huseyin, Robert J. Klose, Matthias Merkenschlager, Amanda G. Fisher
Published 2020-08-01

scRNA-Seq reveals distinct stem cell populations that drive hair cell regeneration after loss of Fgf and Notch signaling

by Mark E Lush, Daniel C Diaz, Nina Koenecke, Sungmin Baek, Helena Boldt, Madeleine K St Peter, Tatiana Gaitan-Escudero, Andres Romero-Carvajal, Elisabeth M Busch-Nentwich, Anoja G Perera, Kathryn E Hall, Allison Peak, Jeffrey S Haug, Tatjana Piotrowski
Published 2019-01-01

Two Cases of Recessive Intellectual Disability Caused by <i>NDST1</i> and <i>METTL23</i> Variants

by Amjad Khan, Zhichao Miao, Muhammad Umair, Amir Ullah, Mohammad A. Alshabeeb, Muhammad Bilal, Farooq Ahmad, Gudrun A. Rappold, Muhammad Ansar, Raphael Carapito
Published 2020-08-01

Gender Differential Transcriptome in Gastric and Thyroid Cancers

by Abel Sousa, Abel Sousa, Abel Sousa, Abel Sousa, Marta Ferreira, Marta Ferreira, Carla Oliveira, Carla Oliveira, Carla Oliveira, Pedro G. Ferreira, Pedro G. Ferreira, Pedro G. Ferreira, Pedro G. Ferreira
Published 2020-07-01

H3Africa: current perspectives

by Mulder N, Abimiku A, Adebamowo SN, de Vries J, Matimba A, Olowoyo P, Ramsay M, Skelton M, Stein DJ
Published 2018-04-01

Sequencing of Supernumerary Chromosomes of Red Fox and Raccoon Dog Confirms a Non-Random Gene Acquisition by B Chromosomes

by Alexey I. Makunin, Svetlana A. Romanenko, Violetta R. Beklemisheva, Polina L. Perelman, Anna S. Druzhkova, Kristina O. Petrova, Dmitry Yu. Prokopov, Ekaterina N. Chernyaeva, Jennifer L. Johnson, Anna V. Kukekova, Fengtang Yang, Malcolm A. Ferguson-Smith, Alexander S. Graphodatsky, Vladimir A. Trifonov
Published 2018-08-01

Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci

by Paulo P. Amaral, Tommaso Leonardi, Namshik Han, Emmanuelle Viré, Dennis K. Gascoigne, Raúl Arias-Carrasco, Magdalena Büscher, Luca Pandolfini, Anda Zhang, Stefano Pluchino, Vinicius Maracaja-Coutinho, Helder I. Nakaya, Martin Hemberg, Ramin Shiekhattar, Anton J. Enright, Tony Kouzarides
Published 2018-03-01

Micro-epidemiological structuring of Plasmodium falciparum parasite populations in regions with varying transmission intensities in Africa. [version 2; referees: 4 approved]

by Irene Omedo, Polycarp Mogeni, Teun Bousema, Kirk Rockett, Alfred Amambua-Ngwa, Isabella Oyier, Jennifer C. Stevenson, Amrish Y. Baidjoe, Etienne P. de Villiers, Greg Fegan, Amanda Ross, Christina Hubbart, Anne Jeffreys, Thomas N. Williams, Dominic Kwiatkowski, Philip Bejon
Published 2017-09-01

The expectations and realities of nutrigenomic testing in australia: A qualitative study

by Erin Tutty, Chriselle Hickerton, Bronwyn Terrill, Belinda McClaren, Rigan Tytherleigh, Elaine Stackpoole, Jaqueline Savard, Ainsley Newson, Anna Middleton, Amy Nisselle, Marie Cusack, Melissa Adamski, Clara Gaff, Sylvia Metcalfe
Published 2021-04-01

Data-driven identification of ageing-related diseases from electronic health records

by Valerie Kuan, Helen C. Fraser, Melanie Hingorani, Spiros Denaxas, Arturo Gonzalez-Izquierdo, Kenan Direk, Dorothea Nitsch, Rohini Mathur, Constantinos A. Parisinos, R. Thomas Lumbers, Reecha Sofat, Ian C. K. Wong, Juan P. Casas, Janet M. Thornton, Harry Hemingway, Linda Partridge, Aroon D. Hingorani
Published 2021-02-01

A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation

by Kimberly F. Breglio, Roberto Amato, Richard Eastman, Pharath Lim, Juliana M. Sa, Rajarshi Guha, Sundar Ganesan, David W. Dorward, Carleen Klumpp-Thomas, Crystal McKnight, Rick M. Fairhurst, David Roberts, Craig Thomas, Anna Katharina Simon
Published 2018-10-01

Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution

by Hansruedi Mathys, Chinnakkaruppan Adaikkan, Fan Gao, Jennie Z. Young, Elodie Manet, Martin Hemberg, Philip L. De Jager, Richard M. Ransohoff, Aviv Regev, Li-Huei Tsai
Published 2017-10-01

Peptides Derived of Kunitz-Type Serine Protease Inhibitor as Potential Vaccine Against Experimental Schistosomiasis

by Juan Hernández-Goenaga, Julio López-Abán, Anna V. Protasio, Belén Vicente Santiago, Esther del Olmo, Magnolia Vanegas, Pedro Fernández-Soto, Manuel Alfonso Patarroyo, Manuel Alfonso Patarroyo, Antonio Muro
Published 2019-11-01