Tumors attenuating the mitochondrial activity in T cells escape from PD-1 blockade therapy

by Alok Kumar, Kenji Chamoto, Partha S Chowdhury, Tasuku Honjo
Published 2020-03-01

Cancer immunotherapies targeting the PD-1 signaling pathway

by Yoshiko Iwai, Junzo Hamanishi, Kenji Chamoto, Tasuku Honjo
Published 2017-04-01

The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombination.

by Andre Stanlie, Nasim A Begum, Hideo Akiyama, Tasuku Honjo
Published 2012-01-01

Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability

by Afzal Husain, Nasim A. Begum, Takako Taniguchi, Hisaaki Taniguchi, Maki Kobayashi, Tasuku Honjo
Published 2016-02-01

In vivo analysis of Aicda gene regulation: a critical balance between upstream enhancers and intronic silencers governs appropriate expression.

by Le Thi Huong, Maki Kobayashi, Mikiyo Nakata, Go Shioi, Hitoshi Miyachi, Tasuku Honjo, Hitoshi Nagaoka
Published 2013-01-01

Human S mu binding protein-2 binds to the drug response element and transactivates the human apoA-I promoter: role of gemfibrozil

by William S. Mohan, Zhang-Qun Chen, Xia Zhang, Kamel Khalili, Tasuku Honjo, Roger G. Deeley, Shui-Pang Tam
Published 1998-02-01

Inactivation of the PD-1-Dependent Immunoregulation in Mice Exacerbates Contact Hypersensitivity Resembling Immune-Related Adverse Events

by Matin Dokht Ashoori, Matin Dokht Ashoori, Kensuke Suzuki, Kensuke Suzuki, Yosuke Tokumaru, Yosuke Tokumaru, Naoko Ikuta, Masaki Tajima, Tasuku Honjo, Akio Ohta
Published 2021-01-01

Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age.

by Hongyan Qin, Keiichiro Suzuki, Mikiyo Nakata, Shunsuke Chikuma, Nakako Izumi, Le Thi Huong, Mikako Maruya, Sidonia Fagarasan, Meinrad Busslinger, Tasuku Honjo, Hitoshi Nagaoka
Published 2011-01-01

Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes

by Gabrielle McDonald, Carlos O. Medina, Monika Pilichowska, John F. Kearney, Reiko Shinkura, Erik Selsing, Henry H. Wortis, Tasuku Honjo, Thereza Imanishi-Kari
Published 2017-09-01

Nobel committee honors tumor immunologists

by Anand Rotte, Gabriella D’Orazi, Madhuri Bhandaru
Published 2018-10-01

PD-1: Its Discovery, Involvement in Cancer Immunotherapy, and Beyond

by Yasumasa Ishida
Published 2020-06-01

Immune checkpoint blockade therapy: The 2014 Tang prize in biopharmaceutical science

by Ya-Shan Chen, Chia-Rui Shen
Published 2015-02-01

Immunological targets for cancer therapy: new recognition

by Shurin MR
Published 2018-11-01

Recent Patent of Immunotherapy in Mainstream Oncology

by Kuen-Wang Tsai, 蔡坤旺
Published 2019

The Intriguing History of Cancer Immunotherapy

by Paula Dobosz, Tomasz Dzieciątkowski
Published 2019-12-01

Differential regulation of S-region hypermutation and class switch recombination by noncanonical functions of uracil DNA glycosylase

by Yousif Ashraf Siddig
Published 2014

Programmed cell death-1 inhibits inflammatory helper T cell development through controlling the innate immune response

by Rui, Yuxiang
Published 2014

Inactivation of the PD-1-dependent immunoregulation in mice exacerbates contact hypersensitivity resembling immune-related adverse events

by Ashoori, Matin Dokht
Published 2021

Activation-induced cytidine deaminase is dispensable for virus-mediated liver and skin tumor development in mouse models

by Nguyen Manh Tung
Published 2014

Immune checkpoint inhibitors win the 2018 Nobel Prize

by Pei-Wei Huang, John Wen-Cheng Chang
Published 2019-10-01