The integrative bioinformatic analysis deciphers the predicted molecular target gene and pathway from curcumin derivative CCA-1.1 against triple-negative breast cancer (TNBC)

by Dhania Novitasari, Riris Istighfari Jenie, Jun-ya Kato, Edy Meiyanto
Published 2021-08-01

PI3K and MAPK Pathways as Targets for Combination with the Pan-HER Irreversible Inhibitor Neratinib in HER2-Positive Breast Cancer and TNBC by Kinome RNAi Screening

by Jangsoon Lee, Huey Liu, Troy Pearson, Toshiaki Iwase, Jon Fuson, Alshad S. Lalani, Lisa D. Eli, Irmina Diala, Debu Tripathy, Bora Lim, Naoto T. Ueno
Published 2021-06-01

B4GALNT2 Gene Promotes Proliferation, and Invasiveness and Migration Abilities of Model Triple Negative Breast Cancer (TNBC) Cells by Interacting With HLA-B Protein

by Pu Yu, Lili Zhu, Kang Cui, Yabing Du, Chaojie Zhang, Wang Ma, Jia Guo
Published 2021-09-01

Distinct Classes of Flavonoids and Epigallocatechin Gallate, Polyphenol Affects an Oncogenic Mutant p53 Protein, Cell Growth and Invasion in a TNBC Breast Cancer Cell Line

by Madhu Kollareddy, Luis A. Martinez
Published 2021-04-01

lncRNA MIR503HG inhibits cell proliferation and promotes apoptosis in TNBC cells via the miR-224-5p/HOXA9 axis

by Shou-Man Wang, Jian Pang, Ke-Jing Zhang, Zhi-Yang Zhou, Fei-Yu Chen
Published 2021-06-01

RhoC Modulates Cell Junctions and Type I Interferon Response in Aggressive Breast Cancers

by Hannah G. Abraham, Peter J. Ulintz, Laura Goo, Joel A. Yates, Andrew C. Little, Liwei Bao, Zhifen Wu, Sofia D. Merajver
Published 2021-08-01

Hypoxia-Mediated Complement 1q Binding Protein Regulates Metastasis and Chemoresistance in Triple-Negative Breast Cancer and Modulates the PKC-NF-κB-VCAM-1 Signaling Pathway

by Hao Wu, Hao Wu, Hao Wu, Yijun Chu, Yijun Chu, Yijun Chu, Shanshan Sun, Shanshan Sun, Shanshan Sun, Guozheng Li, Guozheng Li, Guozheng Li, Shouping Xu, Shouping Xu, Shouping Xu, Xianyu Zhang, Xianyu Zhang, Xianyu Zhang, Yongdong Jiang, Yongdong Jiang, Yongdong Jiang, Song Gao, Song Gao, Song Gao, Qin Wang, Qin Wang, Qin Wang, Jian Zhang, Da Pang, Da Pang, Da Pang, Da Pang
Published 2021-02-01

Effect of N6-Methyladenosine Regulators on Progression and Prognosis of Triple-Negative Breast Cancer

by Shanshan Wang, Shanshan Wang, Xuan Zou, Xuan Zou, Yajie Chen, Yajie Chen, William C. Cho, Xiang Zhou, Xiang Zhou, Xiang Zhou, Xiang Zhou
Published 2021-01-01

Prognostic value of kallikrein-related peptidase 12 (KLK12) mRNA expression in triple-negative breast cancer patients

by Weiwei Gong, Yueyang Liu, Sarah Preis, Xiaocong Geng, Agnes Petit-Courty, Marion Kiechle, Alexander Muckenhuber, Tobias Dreyer, Julia Dorn, Yves Courty, Viktor Magdolen
Published 2020-02-01

HRD1 inhibits fatty acid oxidation and tumorigenesis by ubiquitinating CPT2 in triple‐negative breast cancer

by Xin Guo, Aman Wang, Wen Wang, Ya Wang, Huan Chen, Xiaolong Liu, Tian Xia, Aijia Zhang, Di Chen, Huan Qi, Ting Ling, Hai‐long Piao, Hong‐jiang Wang
Published 2021-02-01

Selinexor (KPT-330) demonstrates anti-tumor efficacy in preclinical models of triple-negative breast cancer

by Natalia Paez Arango, Erkan Yuca, Ming Zhao, Kurt W. Evans, Stephen Scott, Charissa Kim, Ana Maria Gonzalez-Angulo, Filip Janku, Naoto T. Ueno, Debu Tripathy, Argun Akcakanat, Aung Naing, Funda Meric-Bernstam
Published 2017-08-01

Mass Spectrometry-Based Omics for the Characterization of Triple-Negative Breast Cancer Bio-Signature

by Ioana-Ecaterina Pralea, Radu-Cristian Moldovan, Adrian-Bogdan Țigu, Corina Ionescu, Cristina-Adela Iuga
Published 2020-12-01

New Perspectives for Resistance to PARP Inhibitors in Triple-Negative Breast Cancer

by Ye Han, Xiaopeng Yu, Shuqiang Li, Ye Tian, Caigang Liu
Published 2020-11-01

Clinical Significance of Annexin A2 Expression in Breast Cancer Patients

by Lee D. Gibbs, Kelsey Mansheim, Sayantan Maji, Rajesh Nandy, Cheryl M. Lewis, Jamboor K. Vishwanatha, Pankaj Chaudhary
Published 2021-12-01

Ceramide kinase mediates intrinsic resistance and inferior response to chemotherapy in triple‐negative breast cancer by upregulating Ras/ERK and PI3K/Akt pathways

by Shan Zhu, Yulin Xu, Lijun Wang, Shichong Liao, Yuan Wang, Manman Shi, Yi Tu, Yurong Zhou, Wen Wei
Published 2021-01-01

NLRP3 Inflammasome From Bench to Bedside: New Perspectives for Triple Negative Breast Cancer

by Margherita Sonnessa, Antonella Cioffi, Oronzo Brunetti, Nicola Silvestris, Nicola Silvestris, Francesco A. Zito, Concetta Saponaro, Anita Mangia
Published 2020-09-01

Comprehensive analysis and establishment of a prediction model of alternative splicing events reveal the prognostic predictor and immune microenvironment signatures in triple negat...

by Shanshan Yu, Chuan Hu, Lixiao Liu, Luya Cai, Xuedan Du, Qiongjie Yu, Fan Lin, Jinduo Zhao, Ye Zhao, Cheng Zhang, Xuan Liu, Wenfeng Li
Published 2020-07-01

Novel Diphenylamine Analogs Induce Mesenchymal to Epithelial Transition in Triple Negative Breast Cancer

by Akshita B. Bhatt, Mohit Gupta, Van T. Hoang, Suravi Chakrabarty, Thomas D. Wright, Steven Elliot, Ishveen K. Chopra, Darlene Monlish, Katie Anna, Matthew E. Burow, Jane E. Cavanaugh, Patrick T. Flaherty
Published 2019-07-01

ESM-1 Overexpression is Involved in Increased Tumorigenesis of Radiotherapy-Resistant Breast Cancer Cells

by Hana Jin, Trojan Rugira, Young Shin Ko, Sang Won Park, Seung Pil Yun, Hye Jung Kim
Published 2020-05-01

Circular HER2 RNA positive triple negative breast cancer is sensitive to Pertuzumab

by Jie Li, Maoguang Ma, Xuesong Yang, Maolei Zhang, Jingyan Luo, Huangkai Zhou, Nunu Huang, Feizhe Xiao, Bingquan Lai, Weiming Lv, Nu Zhang
Published 2020-09-01