Cold-Pressed <i>Nigella Sativa</i> Oil Standardized to 3% Thymoquinone Potentiates Omega-3 Protection against Obesity-Induced Oxidative Stress, Inflammation, and Markers of Insulin...

by Hsin Hsueh Shen, Stephen J. Peterson, Lars Bellner, Abu Choudhary, Lior Levy, Leah Gancz, Ariel Sasson, Joseph Trainer, Rita Rezzani, Abraham Resnick, David E. Stec, Nader G. Abraham
Published 2020-06-01

Nutritional Mushroom Treatment in Meniere’s Disease with <i>Coriolus versicolor</i>: A Rationale for Therapeutic Intervention in Neuroinflammation and Antineurodegeneration

by Maria Scuto, Paola Di Mauro, Maria Laura Ontario, Chiara Amato, Sergio Modafferi, Domenico Ciavardelli, Angela Trovato Salinaro, Luigi Maiolino, Vittorio Calabrese
Published 2019-12-01

Pirfenidone Is an Agonistic Ligand for PPARα and Improves NASH by Activation of SIRT1/LKB1/pAMPK

by Ana Sandoval‐Rodriguez, Hugo Christian Monroy‐Ramirez, Alejandra Meza‐Rios, Jesus Garcia‐Bañuelos, Jose Vera‐Cruz, Jorge Gutiérrez‐Cuevas, Jorge Silva‐Gomez, Bart Staels, Jose Dominguez‐Rosales, Marina Galicia‐Moreno, Monica Vazquez‐Del Mercado, Jose Navarro‐Partida, Arturo Santos‐Garcia, Juan Armendariz‐Borunda
Published 2020-03-01

Targeting histone deacetylase SIRT1 selectively eradicates EGFR TKI-resistant cancer stem cells via regulation of mitochondrial oxidative phosphorylation in lung adenocarcinoma

by Jiangtao Sun, Guifang Li, Yiwen Liu, Mingyang Ma, Kaifang Song, Huaxu Li, Daxing Zhu, XiaoJun Tang, Jinyu Kong, Xiang Yuan
Published 2020-01-01

MHY2233 Attenuates Replicative Cellular Senescence in Human Endothelial Progenitor Cells via SIRT1 Signaling

by Shreekrishna Lamichane, Sang Hong Baek, Yeon-Ju Kim, Ji Hye Park, Babita Dahal Lamichane, Woong Bi Jang, SeungTaek Ji, Na Kyung Lee, Li Dehua, Da Yeon Kim, Songhwa Kang, Ha Jong Seong, Jisoo Yun, Dong Hyung Lee, Hyung Ryong Moon, Hae Young Chung, Sang-Mo Kwon
Published 2019-01-01

Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity

by Rafael Mayoral, Olivia Osborn, Joanne McNelis, Andrew M. Johnson, Da Young Oh, Cristina Llorente Izquierdo, Heekyung Chung, Pingping Li, Paqui G. Traves, Gautam Bandyopadhyay, Ariane R. Pessentheiner, Jachelle M. Ofrecio, Joshua R. Cook, Li Qiang, Domenico Accili, Jerrold M. Olefsky
Published 2015-05-01

Resveratrol Prevents Right Ventricle Remodeling and Dysfunction in Monocrotaline-Induced Pulmonary Arterial Hypertension with a Limited Improvement in the Lung Vasculature

by Eduardo Vázquez-Garza, Judith Bernal-Ramírez, Carlos Jerjes-Sánchez, Omar Lozano, Edgar Acuña-Morín, Mariana Vanoye-Tamez, Martín R. Ramos-González, Héctor Chapoy-Villanueva, Luis Pérez-Plata, Luis Sánchez-Trujillo, Guillermo Torre-Amione, Alicia Ramírez-Rivera, Gerardo García-Rivas
Published 2020-01-01

Physical Training Regulates Mitochondrial Parameters and Neuroinflammatory Mechanisms in an Experimental Model of Parkinson’s Disease

by Talita Tuon, Priscila S. Souza, Marcela F. Santos, Fernanda T. Pereira, Giulia S. Pedroso, Thais F. Luciano, Claudio T. De Souza, Rafael C. Dutra, Paulo C. L. Silveira, Ricardo A. Pinho
Published 2015-01-01

Inhibition of miR-449a Promotes Cartilage Regeneration and Prevents Progression of Osteoarthritis in In Vivo Rat Models

by Dawoon Baek, Kyoung-Mi Lee, Ki Won Park, Jae Wan Suh, Seong Mi Choi, Kwang Hwan Park, Jin Woo Lee, Sung-Hwan Kim
Published 2018-12-01

Hepatic DNA Damage Induced by Electronic Cigarette Exposure Is Associated With the Modulation of NAD+/PARP1/SIRT1 Axis

by Jorge Espinoza-Derout, Xuesi M. Shao, Xuesi M. Shao, Emmanuel Bankole, Kamrul M. Hasan, Norma Mtume, Yanjun Liu, Yanjun Liu, Amiya P. Sinha-Hikim, Amiya P. Sinha-Hikim, Theodore C. Friedman, Theodore C. Friedman
Published 2019-06-01

The role of miR-101 and miR-135a in reprogramming of somatic cells into induced pluripotent stem cells

by Chen, Chun-hang, 陳進鏗
Published 2013

Tangshen Formula Alleviates Hepatic Steatosis by Inducing Autophagy Through the AMPK/SIRT1 Pathway

by Yan Wang, Yan Wang, Hailing Zhao, Xin Li, Nan Li, Nan Li, Qian Wang, Qian Wang, Yanzhen Liu, Yanzhen Liu, Qionglin Liang, Zixing Shao, Nannan Zhang, Tingting Zhao, Liang Peng, Ping Li, Ping Li
Published 2019-04-01

Deletion of intestinal SIRT1 exacerbated muscle wasting in cirrhotic mice by decreasing the intestinal concentration of short-chain fatty acids and inflammation

by Chien-Fu Hsu, Chia-Chang Huang, Tze-Tze Liu, Ueng-Cheng Yang, Chih-Wei Liu, Shiang-Fen Huang, Ying-Ying Yang, Yi-Hsiang Huang, Ming-Chih Hou, Han-Chieh Lin
Published 2021-12-01

Dietary glutamine, glutamate, and aspartate supplementation improves hepatic lipid metabolism in post-weaning piglets

by Ming Qi, Jing Wang, Bi'e Tan, Jianjun Li, Simeng Liao, Yanhong Liu, Yulong Yin
Published 2020-06-01

p53 Deacetylation Alleviates Sepsis-Induced Acute Kidney Injury by Promoting Autophagy

by Maomao Sun, Maomao Sun, Jiaxin Li, Jiaxin Li, Liangfeng Mao, Liangfeng Mao, Jie Wu, Zhiya Deng, Man He, Sheng An, Zhenhua Zeng, Zhenhua Zeng, Qiaobing Huang, Qiaobing Huang, Zhongqing Chen, Zhongqing Chen
Published 2021-07-01

Geniposide Alleviates Isoproterenol-Induced Cardiac Fibrosis Partially via SIRT1 Activation in vivo and in vitro

by Ning Li, Ning Li, Ning Li, Heng Zhou, Heng Zhou, Heng Zhou, Zhen-Guo Ma, Zhen-Guo Ma, Zhen-Guo Ma, Jin-Xiu Zhu, Jin-Xiu Zhu, Jin-Xiu Zhu, Chen Liu, Chen Liu, Chen Liu, Peng Song, Peng Song, Peng Song, Chun-Yan Kong, Chun-Yan Kong, Chun-Yan Kong, Hai-Ming Wu, Hai-Ming Wu, Hai-Ming Wu, Wei Deng, Wei Deng, Wei Deng, Qi-Zhu Tang, Qi-Zhu Tang, Qi-Zhu Tang
Published 2018-08-01

Alteracoes metabolicas decorrentes da delecao genica da enzima conversora de angiotensina 2 - ECA2 - em camundongos

by Souza, Valéria Nunes de
Published 2017

Angiotensin-(1-7)/Mas Axis Compensates Absent Bradykinin in <i>Bdkrb2^-/-</i> and <i>Klkb1^-/-</i> Mice to Regulate Thrombosis Risk

by Fang, Chao
Published 2014

Attenuation of Pb-induced Aβ generation and autophagic dysfunction via activation of SIRT1: Neuroprotective properties of resveratrol

by Lin Bai, Rundong Liu, Ruike Wang, Yongjuan Xin, Zuntao Wu, Yue Ba, Huizhen Zhang, Xuemin Cheng, Guoyu Zhou, Hui Huang
Published 2021-10-01

Metabolic and Molecular Subacute Effects of a Single Moderate-Intensity Exercise Bout, Performed in the Fasted State, in Obese Male Rats

by Éverton Lopes Vogt, Maiza Cristina Von Dentz, Débora Santos Rocha, Jorge Felipe Argenta Model, Lucas Stahlhöfer Kowalewski, Samir Khal de Souza, Vitória de Oliveira Girelli, Paulo Ivo Homem de Bittencourt, Rogério Friedman, Mauricio Krause, Anapaula Sommer Vinagre
Published 2021-07-01