Quantitative informant‐ and self‐reports of subjective cognitive decline predict amyloid beta PET outcomes in cognitively unimpaired individuals independently of age and APOE ε4...

by Gonzalo Sánchez‐Benavides, Gemma Salvadó, Eider M. Arenaza‐Urquijo, Oriol Grau‐Rivera, Marc Suárez‐Calvet, Marta Milà‐Alomà, José María González‐de‐Echávarri, Carolina Minguillon, Marta Crous‐Bou, Aida Niñerola‐Baizán, Andrés Perissinotti, Juan Domingo Gispert, José Luis Molinuevo, for the ALFA Study
Published 2020-01-01

Cognitively unimpaired individuals with a low burden of Aβ pathology have a distinct CSF biomarker profile

by Marta Milà-Alomà, Mahnaz Shekari, Gemma Salvadó, Juan Domingo Gispert, Eider M. Arenaza-Urquijo, Grégory Operto, Carles Falcon, Natalia Vilor-Tejedor, Oriol Grau-Rivera, Aleix Sala-Vila, Gonzalo Sánchez-Benavides, José Maria González-de-Echávarri, Carolina Minguillon, Karine Fauria, Aida Niñerola-Baizán, Andrés Perissinotti, Maryline Simon, Gwendlyn Kollmorgen, Henrik Zetterberg, Kaj Blennow, Marc Suárez-Calvet, José Luis Molinuevo, for the ALFA study
Published 2021-07-01

Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer’s continuum when only subtle changes in Aβ pathology are detected...

by Marc Suárez‐Calvet, Thomas K Karikari, Nicholas J Ashton, Juan Lantero Rodríguez, Marta Milà‐Alomà, Juan Domingo Gispert, Gemma Salvadó, Carolina Minguillon, Karine Fauria, Mahnaz Shekari, Oriol Grau‐Rivera, Eider M Arenaza‐Urquijo, Aleix Sala‐Vila, Gonzalo Sánchez‐Benavides, José Maria González‐de‐Echávarri, Gwendlyn Kollmorgen, Erik Stoops, Eugeen Vanmechelen, Henrik Zetterberg, Kaj Blennow, José Luis Molinuevo, for the ALFA Study
Published 2020-12-01

Brain and cognitive correlates of subjective cognitive decline-plus features in a population-based cohort

by Gonzalo Sánchez-Benavides, Oriol Grau-Rivera, Marc Suárez-Calvet, Carolina Minguillon, Raffaele Cacciaglia, Nina Gramunt, Carles Falcon, ALFA Study, Juan Domingo Gispert, José Luis Molinuevo
Published 2018-12-01

Perivascular spaces are associated with tau pathophysiology and synaptic dysfunction in early Alzheimer’s continuum

by Natalia Vilor-Tejedor, Iacopo Ciampa, Grégory Operto, Carles Falcón, Marc Suárez-Calvet, Marta Crous-Bou, Mahnaz Shekari, Eider M. Arenaza-Urquijo, Marta Milà-Alomà, Oriol Grau-Rivera, Carolina Minguillon, Gwendlyn Kollmorgen, Henrik Zetterberg, Kaj Blennow, Roderic Guigo, José Luis Molinuevo, Juan Domingo Gispert, for the ALFA study
Published 2021-08-01

Association between insomnia and cognitive performance, gray matter volume, and white matter microstructure in cognitively unimpaired adults

by Oriol Grau-Rivera, Grégory Operto, Carles Falcón, Gonzalo Sánchez-Benavides, Raffaele Cacciaglia, Anna Brugulat-Serrat, Nina Gramunt, Gemma Salvadó, Marc Suárez-Calvet, Carolina Minguillon, Álex Iranzo, Juan Domingo Gispert, José Luis Molinuevo, for the ALFA Study
Published 2020-01-01

Association of weight change with cerebrospinal fluid biomarkers and amyloid positron emission tomography in preclinical Alzheimer’s disease

by Oriol Grau-Rivera, Irene Navalpotro-Gomez, Gonzalo Sánchez-Benavides, Marc Suárez-Calvet, Marta Milà-Alomà, Eider M. Arenaza-Urquijo, Gemma Salvadó, Aleix Sala-Vila, Mahnaz Shekari, José Maria González-de-Echávarri, Carolina Minguillón, Aida Niñerola-Baizán, Andrés Perissinotti, Maryline Simon, Gwendlyn Kollmorgen, Henrik Zetterberg, Kaj Blennow, Juan Domingo Gispert, José Luis Molinuevo, for the ALFA Study
Published 2021-02-01

APOE-ε4 risk variant for Alzheimer's disease modifies the association between cognitive performance and cerebral morphology in healthy middle-aged individuals

by Raffaele Cacciaglia, José Luis Molinuevo, Carles Falcón, Gonzalo Sánchez-Benavides, Nina Gramunt, Anna Brugulat-Serrat, Manel Esteller, Sebastián Morán, Karine Fauria, Juan Domingo Gispert
Published 2019-01-01

Centiloid cut-off values for optimal agreement between PET and CSF core AD biomarkers

by Gemma Salvadó, José Luis Molinuevo, Anna Brugulat-Serrat, Carles Falcon, Oriol Grau-Rivera, Marc Suárez-Calvet, Javier Pavia, Aida Niñerola-Baizán, Andrés Perissinotti, Francisco Lomeña, Carolina Minguillon, Karine Fauria, Henrik Zetterberg, Kaj Blennow, Juan Domingo Gispert, for the Alzheimer’s Disease Neuroimaging Initiative, for the ALFA Study
Published 2019-03-01

Spatial patterns of white matter hyperintensities associated with Alzheimer’s disease risk factors in a cognitively healthy middle-aged cohort

by Gemma Salvadó, Anna Brugulat-Serrat, Carole H. Sudre, Oriol Grau-Rivera, Marc Suárez-Calvet, Carles Falcon, Karine Fauria, M. Jorge Cardoso, Frederik Barkhof, José Luis Molinuevo, Juan Domingo Gispert, for the ALFA Study
Published 2019-01-01

Interactive effect of age and APOE-ε4 allele load on white matter myelin content in cognitively normal middle-aged subjects

by Grégory Operto, José Luis Molinuevo, Raffaele Cacciaglia, Carles Falcon, Anna Brugulat-Serrat, Marc Suárez-Calvet, Oriol Grau-Rivera, Nuria Bargalló, Sebastián Morán, Manel Esteller, Juan Domingo Gispert
Published 2019-01-01

Associations between air pollution and biomarkers of Alzheimer’s disease in cognitively unimpaired individuals

by Silvia Alemany, Marta Crous-Bou, Natalia Vilor-Tejedor, Marta Milà-Alomà, Marc Suárez-Calvet, Gemma Salvadó, Marta Cirach, Eider M. Arenaza-Urquijo, Gonzalo Sanchez-Benavides, Oriol Grau-Rivera, Carolina Minguillon, Karine Fauria, Gwendlyn Kollmorgen, Juan Domingo Gispert, Mireia Gascón, Mark Nieuwenhuijsen, Henrik Zetterberg, Kaj Blennow, Jordi Sunyer, José Luis Molinuevo
Published 2021-12-01

Modeling practice effects in healthy middle‐aged participants of the Alzheimer and Families parent cohort

by Gonzalo Sánchez‐Benavides, Juan D. Gispert, Karine Fauria, José Luis Molinuevo, Nina Gramunt
Published 2016-01-01

White matter microstructure is altered in cognitively normal middle-aged APOE-ε4 homozygotes

by Grégory Operto, Raffaele Cacciaglia, Oriol Grau-Rivera, Carles Falcon, Anna Brugulat-Serrat, Pablo Ródenas, Rubén Ramos, Sebastián Morán, Manel Esteller, Nuria Bargalló, José Luis Molinuevo, Juan Domingo Gispert, for the ALFA Study
Published 2018-05-01

Genetic Predisposition to Alzheimer’s Disease Is Associated with Enlargement of Perivascular Spaces in Centrum Semiovale Region

by Iacopo Ciampa, Grégory Operto, Carles Falcon, Carolina Minguillon, Manuel Castro de Moura, David Piñeyro, Manel Esteller, Jose Luis Molinuevo, Roderic Guigó, Arcadi Navarro, Juan Domingo Gispert, Natalia Vilor-Tejedor, for the ALFA Study
Published 2021-05-01

Impact of urban environmental exposures on cognitive performance and brain structure of healthy individuals at risk for Alzheimer’s dementia

by Marta Crous-Bou, Mireia Gascon, Juan Domingo Gispert, Marta Cirach, Gonzalo Sánchez-Benavides, Carles Falcon, Eider M. Arenaza-Urquijo, Xavier Gotsens, Karine Fauria, Jordi Sunyer, Mark J. Nieuwenhuijsen, José Luis Molinuevo
Published 2020-05-01

Longitudinal structural cerebral changes related to core CSF biomarkers in preclinical Alzheimer's disease: A study of two independent datasets

by Carles Falcon, Alan Tucholka, Gemma C. Monté-Rubio, Raffaele Cacciaglia, Grégory Operto, Lorena Rami, Juan Domingo Gispert, José Luis Molinuevo
Published 2018-01-01

Alzheimer’s disease prevention: from risk factors to early intervention

by Marta Crous-Bou, Carolina Minguillón, Nina Gramunt, José Luis Molinuevo
Published 2017-09-01

Prediction of amyloid pathology in cognitively unimpaired individuals using voxel-wise analysis of longitudinal structural brain MRI

by Paula M. Petrone, Adrià Casamitjana, Carles Falcon, Miquel Artigues, Grégory Operto, Raffaele Cacciaglia, José Luis Molinuevo, Verónica Vilaplana, Juan Domingo Gispert, for the Alzheimer’s Disease Neuroimaging Initiative
Published 2019-08-01

A whole-brain computational modeling approach to explain the alterations in resting-state functional connectivity during progression of Alzheimer's disease

by Murat Demirtaş, Carles Falcon, Alan Tucholka, Juan Domingo Gispert, José Luis Molinuevo, Gustavo Deco
Published 2017-01-01