Cystathionine-β-Synthase Inhibition for Colon Cancer: Enhancement of the Efficacy of Aminooxyacetic Acid via the Prodrug Approach

by Celia Chao, John R Zatarain, Ye Ding, Ciro Coletta, Amy A Mrazek, Nadiya Druzhyna, Paul Johnson, Haiying Chen, Judy L Hellmich, Antonia Asimakopoulou, Kazunori Yanagi, Gabor Olah, Petra Szoleczky, Gabor Törö, Fredrick J Bohanon, Minal Cheema, Rachel Lewis, David Eckelbarger, Akbar Ahmad, Katalin Módis, Ashley Untereiner, Bartosz Szczesny, Andreas Papapetropoulos, Jia Zhou, Mark R Hellmich, Csaba Szabo
Published 2016-05-01

Toll-Like Receptor 9 Enhances Bacterial Clearance and Limits Lung Consolidation in Murine Pneumonia Caused by Methicillin-Resistant Staphylococcus aureus

by Anne Jan van der Meer, Achmed Achouiti, Arie van der Ende, Aicha Ait Soussan, Sandrine Florquin, Alex de Vos, Sacha S Zeerleder, Tom van der Poll
Published 2016-06-01

Compartmentation of Metabolites in Regulating Epigenomes of Cancer

by Zhiqiang Zhao, Li Wang, Li-jun Di
Published 2016-04-01

Liraglutide Enhances the Efficacy of Human Mesenchymal Stem Cells in Preserving Islet ß-cell Function in Severe Non-obese Diabetic Mice

by Li-rong Li, Jing Lu, Xiao-lei Jia, Hui Hui, Jie Zhang, Ying Liu, Wei-juan Cui, Qian-yue Xu, Da-long Zhu
Published 2016-11-01

Cadherin 13: Human cis-Regulation and Selectively Altered Addiction Phenotypes and Cerebral Cortical Dopamine in Knockout Mice

by Jana Drgonova, Donna Walther, G. Luke Hartstein, Mohammad O. Bukhari, Michael H. Baumann, Jonathan Katz, F. Scott Hall, Elizabeth R. Arnold, Shaun Flax, Anthony Riley, Olga Rivero, Klaus-Peter Lesch, Juan Troncoso, Barbara Ranscht, George R. Uhl
Published 2016-08-01

Stachydrine protects eNOS uncoupling and ameliorates endothelial dysfunction induced by homocysteine

by Xinya Xie, Zihui Zhang, Xinfeng Wang, Zhenyu Luo, Baochang Lai, Lei Xiao, Nanping Wang
Published 2018-03-01

Different sulfonylureas induce the apoptosis of proximal tubular epithelial cell differently via closing KATP channel

by Rui Zhang, Xiaojun Zhou, Xue Shen, Tianyue Xie, Chunmei Xu, Zhiwei Zou, Jianjun Dong, Lin Liao
Published 2018-09-01

Three Interacting Genomic Loci Incorporating Two Novel Mutations Underlie the Evolution of Diet-induced Diabetes

by Yoram Yagil, Barak Markus, Refael Kohen, Chana Yagil
Published 2016-07-01

Interleukin-26 Production in Human Primary Bronchial Epithelial Cells in Response to Viral Stimulation: Modulation by Th17 cytokines

by Karlhans Fru Che, Riitta Kaarteenaho, Elisa Lappi-Blanco, Bettina Levänen, Jitong Sun, Åsa Wheelock, Lena Palmberg, C. Magnus Sköld, Anders Lindén
Published 2017-08-01

Adipose Tissue and Serum CCDC80 in Obesity and Its Association with Related Metabolic Disease

by Óscar Osorio-Conles, María Guitart, José María Moreno-Navarrete, Xavier Escoté, Xavier Duran, José Manuel Fernandez-Real, Anna María Gómez-Foix, Sonia Fernández-Veledo, Joan Vendrell
Published 2017-08-01

Shock Wave Therapy Enhances Angiogenesis through VEGFR2 Activation and Recycling

by Tien-Hung Huang, Cheuk-Kwan Sun, Yi-Ling Chen, Ching-Jen Wang, Tsung-Cheng Yin, Mel S Lee, Hon-Kan Yip
Published 2016-12-01

The Transcription Factor XBP1 in Memory and Cognition: implications in Alzheimer’s Disease

by Moustapha Cissé, Eric Duplan, Frédéric Checler
Published 2017-01-01

Low MiR-187 Expression Promotes Resistance to Chemoradiation Therapy In Vitro and Correlates with Treatment Failure in Patients with Esophageal Adenocarcinoma

by Niamh Lynam-Lennon, Becky A S Bibby, Ann Marie Mongan, Laure Marignol, Christian N Paxton, Katherine Geiersbach, Mary P Bronner, Jacintha O’Sullivan, John V Reynolds, Stephen G Maher
Published 2016-05-01

Altered Redox Mitochondrial Biology in the Neurodegenerative Disorder Fragile X-Tremor/Ataxia Syndrome: Use of Antioxidants in Precision Medicine

by Gyu Song, Eleonora Napoli, Sarah Wong, Randi Hagerman, Siming Liu, Flora Tassone, Cecilia Giulivi
Published 2016-06-01

A Journey in Science: Cell-Cycle Control

by Paul Nurse
Published 2017-05-01

Exploring the biological functional mechanism of the HMGB1/TLR4/MD-2 complex by surface plasmon resonance

by Mingzhu He, Marco E. Bianchi, Tom R. Coleman, Kevin J. Tracey, Yousef Al-Abed
Published 2018-05-01

Binding of CLL Subset 4 B Cell Receptor Immunoglobulins to Viable Human Memory B Lymphocytes Requires a Distinctive IGKV Somatic Mutation

by Rosa Catera, Yun Liu, Chao Gao, Xiao-Jie Yan, Amanda Magli, Steven L. Allen, Jonathan E. Kolitz, Kanti R. Rai, Charles C. Chu, Ten Feizi, Kostas Stamatopoulos, Nicholas Chiorazzi
Published 2017-01-01

Matrix Metalloproteinase-8 Augments Bacterial Clearance in a Juvenile sepsis Model

by Sarah J Atkinson, Brian M Varisco, Mary Sandquist, Meghan N Daly, Lindsey Klingbeil, Joshua W Kuethe, Emily F Midura, Kelli Harmon, Amy Opoka, Patrick Lahni, Giovanna Piraino, Paul Hake, Basilia Zingarelli, Joel E Mortensen, James L Wynn, Hector R Wong
Published 2016-08-01

Obesity Paradox, Obesity Orthodox, and the Metabolic Syndrome: An Approach to Unity

by Jesse Roth, Navneet Sahota, Priya Patel, Syed F Mehdi, Mohammad M Wiese, Hafiz B Mahboob, Michelle Bravo, Daniel J Eden, Muhammad A Bashir, Amrat Kumar, Farah Alsaati, Irwin J Kurland, Wunnie Brima, Ann Danoff, Alessandra L Szulc, Valentin A Pavlov, Kevin J Tracey, Huan Yang
Published 2016-11-01

Developing Connections among B Lymphocytes and Deregulated Pathways in Autoimmunity

by Moncef Zouali, Gregory Tsay
Published 2016-10-01