The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling

by Seyed Javad Rasouli, Mohamed El-Brolosy, Ayele Taddese Tsedeke, Anabela Bensimon-Brito, Parisa Ghanbari, Hans-Martin Maischein, Carsten Kuenne, Didier Y Stainier
Published 2018-12-01

Distinct myocardial lineages break atrial symmetry during cardiogenesis in zebrafish

by Almary Guerra, Raoul FV Germano, Oliver Stone, Rima Arnaout, Stefan Guenther, Suchit Ahuja, Verónica Uribe, Benoit Vanhollebeke, Didier YR Stainier, Sven Reischauer
Published 2018-05-01

20-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1

by Sorin Tunaru, Remy Bonnavion, Isabell Brandenburger, Jens Preussner, Dominique Thomas, Klaus Scholich, Stefan Offermanns
Published 2018-01-01

HMGA proteins as modulators of chromatin structure during transcriptional activation

by Nihan eOzturk, Indrabahadur eSingh, Aditi eMehta, Thomas eBraun, Guillermo eBarreto
Published 2014-03-01

Targeting miR‐34a/Pdgfra interactions partially corrects alveologenesis in experimental bronchopulmonary dysplasia

by Jordi Ruiz‐Camp, Jennifer Quantius, Ettore Lignelli, Philipp F Arndt, Francesco Palumbo, Claudio Nardiello, David E Surate Solaligue, Elpidoforos Sakkas, Ivana Mižíková, José Alberto Rodríguez‐Castillo, István Vadász, William D Richardson, Katrin Ahlbrecht, Susanne Herold, Werner Seeger, Rory E Morty
Published 2019-03-01

Transient cardiomyocyte fusion regulates cardiac development in zebrafish

by Suphansa Sawamiphak, Zacharias Kontarakis, Alessandro Filosa, Sven Reischauer, Didier Y. R. Stainier
Published 2017-11-01

Metabolic modulation regulates cardiac wall morphogenesis in zebrafish

by Ryuichi Fukuda, Alla Aharonov, Yu Ting Ong, Oliver A Stone, Mohamed El-Brolosy, Hans-Martin Maischein, Michael Potente, Eldad Tzahor, Didier YR Stainier
Published 2019-12-01

Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice

by ShengPeng Wang, Shuang Cao, Malika Arhatte, Dahui Li, Yue Shi, Sabrina Kurz, Jiong Hu, Lei Wang, Jingchen Shao, Ann Atzberger, Zheng Wang, Changhe Wang, Weijin Zang, Ingrid Fleming, Nina Wettschureck, Eric Honoré, Stefan Offermanns
Published 2020-05-01

Radial glia regulate vascular patterning around the developing spinal cord

by Ryota L Matsuoka, Michele Marass, Avdesh Avdesh, Christian SM Helker, Hans-Martin Maischein, Ann S Grosse, Harmandeep Kaur, Nathan D Lawson, Wiebke Herzog, Didier YR Stainier
Published 2016-11-01

YAP/TAZ Are Required to Suppress Osteogenic Differentiation of Vascular Smooth Muscle Cells

by Lei Wang, Ramesh Chennupati, Young-June Jin, Rui Li, ShengPeng Wang, Stefan Günther, Stefan Offermanns
Published 2020-12-01

Animal Models and “Omics” Technologies for Identification of Novel Biomarkers and Drug Targets to Prevent Heart Failure

by Yunlong Hou, Juan M. Adrian-Segarra, Manfred Richter, Natalia Kubin, Jaeyoung Shin, Isabella Werner, Thomas Walther, Markus Schönburg, Jochen Pöling, Henning Warnecke, Thomas Braun, Sawa Kostin, Thomas Kubin
Published 2015-01-01

Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic Muscles

by Krishnamoorthy Sreenivasan, Alessandro Ianni, Carsten Künne, Boris Strilic, Stefan Günther, Eusebio Perdiguero, Marcus Krüger, Simone Spuler, Stefan Offermanns, Pablo Gómez-del Arco, Juan Miguel Redondo, Pura Munoz-Canoves, Johnny Kim, Thomas Braun
Published 2020-05-01

UROPA: a tool for Universal RObust Peak Annotation

by Maria Kondili, Annika Fust, Jens Preussner, Carsten Kuenne, Thomas Braun, Mario Looso
Published 2017-06-01

Apelin signaling drives vascular endothelial cells toward a pro-angiogenic state

by Christian SM Helker, Jean Eberlein, Kerstin Wilhelm, Toshiya Sugino, Julian Malchow, Annika Schuermann, Stefan Baumeister, Hyouk-Bum Kwon, Hans-Martin Maischein, Michael Potente, Wiebke Herzog, Didier YR Stainier
Published 2020-09-01

The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression

by Alessandra Gentile, Anabela Bensimon-Brito, Rashmi Priya, Hans-Martin Maischein, Janett Piesker, Stefan Guenther, Felix Gunawan, Didier YR Stainier
Published 2021-06-01

Depletion of Numb and Numblike in Murine Lung Epithelial Cells Ameliorates Bleomycin-Induced Lung Fibrosis by Inhibiting the β-Catenin Signaling Pathway

by Alessandro Ianni, Michael Hofmann, Poonam Kumari, Shahriar Tarighi, Hamza M Al-Tamari, André Görgens, Bernd Giebel, Hendrik Nolte, Marcus Krüger, Isabelle Salwig, Isabelle Salwig, Soni Savai Pullamsetti, Soni Savai Pullamsetti, Andreas Günther, Andreas Günther, André Schneider, Thomas Braun, Thomas Braun
Published 2021-05-01

Myogenic vasoconstriction requires G12/G13 and LARG to maintain local and systemic vascular resistance

by Ramesh Chennupati, Angela Wirth, Julie Favre, Rui Li, Rémy Bonnavion, Young-June Jin, Astrid Wietelmann, Frank Schweda, Nina Wettschureck, Daniel Henrion, Stefan Offermanns
Published 2019-09-01

Transcriptional adaptation in Caenorhabditis elegans

by Vahan Serobyan, Zacharias Kontarakis, Mohamed A El-Brolosy, Jordan M Welker, Oleg Tolstenkov, Amr M Saadeldein, Nicholas Retzer, Alexander Gottschalk, Ann M Wehman, Didier YR Stainier
Published 2020-01-01

Endothelial TGF-β signaling instructs smooth muscle cell development in the cardiac outflow tract

by Giulia LM Boezio, Anabela Bensimon-Brito, Janett Piesker, Stefan Guenther, Christian SM Helker, Didier YR Stainier
Published 2020-09-01

Metabolism in tumour-associated macrophages: a quid pro quo with the tumour microenvironment

by Xiang Zheng, Siavash Mansouri, Annika Krager, Friedrich Grimminger, Werner Seeger, Soni S. Pullamsetti, Craig E. Wheelock, Rajkumar Savai
Published 2020-10-01