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MAPK/ERK pathway
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769-P cell line
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786-O cell line
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CRAF
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CRISPR-CAS9 system
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Caki-1 cell line
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HEK293T cell line
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Hepatoblastoma
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IC50
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LHX2
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MAPK signaling
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Medicine and Nursing
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Phosphodiesterase 4D
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RNA extraction
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Raf protein
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Tyrosine kinase inhibitor
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Western blotting
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Wnt pathway
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antineoplastic activity
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apoptosis
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cAMP
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cell cycle arrest
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cell growth
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141“... to downregulation of YB1, and this effect was mediated by the NF-kB and MAPK–ERK pathways. AA may be useful...”
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142by Masafumi Taniwaki, Mihoko Yoshida, Yosuke Matsumoto, Kazuho Shimura, Junya Kuroda, Hiroto Kaneko“...-2 to the phospholipase Cg enzymes SH2 domain leads to enhanced Ca2+. Influx and MAPK/Erk pathway...”
Published 2018-02-01
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143“... found that MAPK/ERK pathway represented the main molecular mechanism underlying the effects of NUDT21...”
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144“... cancer cell. GA regulated the cell proliferation via the PI3K/AKT and MAPK/ERK pathway...”
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145by Pulkkinen Ville, Sundman Lilli, Adner Mikael, Bruce Sara, Anedda Francesca, Vendelin Johanna, Pietras Christina, Alenius Harri, D'Amato Mauro, Söderhäll Cilla, Kere Juha“.../ERK pathway specific reporter assays.</p> <p>Results</p> <p>NPSR1-B signalled through the same...”
Published 2011-06-01
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146“... integrin alpha2 gene via a MAPK/ERK pathway. Blockage of the functions of CYR61 by integrin alpha2...”
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147“... receptor of BDNF) protein expression. The downstream PI3K/AKT and MAPK/ERK pathway of TrkB receptor have...”
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148“... inhibited TSGH-8301 bladder cancer cell proliferation via the PI3K/Akt and MAPK/ERK pathway. Our results...”
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149“... was enhanced by the positive-feedback release or expression of HMGB1 and RAGE through the MAPK-ERK pathway...”
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151by Helena Escuin-Ordinas, Shuoran Li, Michael W. Xie, Lu Sun, Willy Hugo, Rong Rong Huang, Jing Jiao, Felipe Meira de-Faria, Susan Realegeno, Paige Krystofinski, Ariel Azhdam, Sara Marie D. Komenan, Mohammad Atefi, Begoña Comin-Anduix, Matteo Pellegrini, Alistair J. Cochran, Robert L. Modlin, Harvey R. Herschman, Roger S. Lo, William H. McBride, Tatiana Segura, Antoni Ribas“..., the authors demonstrate that BRAF inhibitors can be used to enhance skin wound healing through the MAPK- ERK...”
Published 2016-08-01
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152“... not influence the MAPK/ERK pathway activity, it had a strong influence on melanoma cells, in which this pathway...”
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153by Ana Isabel Oliveira, Sandra I. Anjo, Joana Vieira de Castro, Sofia C. Serra, António J. Salgado, Bruno Manadas, Bruno M. Costa“... of particular intracellular cancer-related pathways, mainly the MAPK/ERK pathway, which is a known regulator...”
Published 2017-10-01
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154by Rafiee Mohammad, Keramati Mohammad Reza, Ayatollahi Hosein, Sadeghian Mohammad Hadi, Barzegar Mohieddin, Asgharzadeh Ali, Alinejad Mohsen“... of the MAPK/ERK pathway and an important tumor suppressor which inhibits ERK trafficking. Decrease in RSK4...”
Published 2016-07-01
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155by Heidi G. Parker, Deepika Dhawan, Alex C. Harris, Jose A. Ramos-Vara, Brian W. Davis, Deborah W. Knapp, Elaine A. Ostrander“... regulated in association with an activating mutation in the MAPK/ERK pathway in canine iUC tumors...”
Published 2020-03-01
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156by Samer Nicolas, Sandra Abdellatef, Maria Al Haddad, Isabelle Fakhoury, Mirvat El-Sibai“...-activated protein kinase/extracellular regulated kinase (MAPK/ERK) pathway and the Phosphatidylinositol-3...”
Published 2019-11-01
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157by Roula Tahtouh, Anne-Sophie Azzi, Nada Alaaeddine, Soulaima Chamat, Hasnaa Bouharoun-Tayoun, Layal Wardi, Issam Raad, Riad Sarkis, Najibe Abou Antoun, George Hilal“.... In contrast, the MAPK/ERK pathway appeared to not be involved in HepG2/C3A cells, whereas ERK inhibition...”
Published 2015-01-01
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158“... signaling patterns. GSB-106 activated the PI3K/AKT and MAPK/ERK pathways simultaneously, whereas GSB-214...”
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159“... pathway:JAK/STAT、PI3K/AKT、MAPK/ERK pathway. All the effect on signal transduction pathway or gene regulated...”
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160by Viviane Younes Rapozo“... signal-regulated kinase (MAPK/ERK) pathway is important for both long-term survival and timing...”
Published 2009
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