Showing 1 - 2 results of 2 for search '"Knudson hypothesis"', query time: 1.31s Refine Results
  1. 1
    Cancerous Protein Network That Inhibits the Tumor Suppressor Function of WW Domain-Containing Oxidoreductase (WWOX) by Aberrantly Expressed Molecules
    by Chiemi Saigo, Yusuke Kito, Tamotsu Takeuchi
    Published 2018-08-01
    “... of the canonical Knudson hypothesis. Impairment of both alleles of WWOX is thought to be a rare event, only...”
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    Article
  2. 2
    The negative feedback-loop between the oncomir Mir-24-1 and menin modulates the Men1 tumorigenesis by mimicking the "Knudson's second hit".
    “... and menin protein, that mimics the second hit of Knudson's hypothesis and that could buffer the effect...”
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