Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia

by Sonja Suvakov, Hajrunisa Cubro, Wendy M. White, Yvonne S. Butler Tobah, Tracey L. Weissgerber, Kyra L. Jordan, Xiang Y. Zhu, John R. Woollard, Fouad T. Chebib, Natasa M. Milic, Joseph P. Grande, Ming Xu, Tamara Tchkonia, James L. Kirkland, Lilach O. Lerman, Vesna D. Garovic
Published 2019-09-01

GPR40 partial agonist MK-2305 lower fasting glucose in the Goto Kakizaki rat via suppression of endogenous glucose production.

by Corin Miller, Michele J Pachanski, Melissa E Kirkland, Daniel T Kosinski, Joel Mane, Michelle Bunzel, Jin Cao, Sarah Souza, Brande Thomas-Fowlkes, Jerry Di Salvo, Adam B Weinglass, Xiaoyan Li, Robert W Myers, Kevin Knagge, Paul E Carrington, William K Hagmann, Maria E Trujillo
Published 2017-01-01

Epigenetic and senescence markers indicate an accelerated ageing-like state in women with preeclamptic pregnancies

by Sonja Suvakov, Ranine Ghamrawi, Hajrunisa Cubro, Haitao Tu, Wendy M. White, Yvonne S. Butler Tobah, Natasa M. Milic, Joseph P. Grande, Julie M. Cunningham, Fouad T. Chebib, Larissa G.P. Langhi Prata, Yi Zhu, Tamara Tchkonia, James L. Kirkland, Karl A. Nath, Aleksandar Milosavljevic, Vesna D. Garovic
Published 2021-08-01

Infrared nano-spectroscopy of ferroelastic domain walls in hybrid improper ferroelectric Ca3Ti2O7

by K. A. Smith, E. A. Nowadnick, S. Fan, O. Khatib, S. J. Lim, B. Gao, N. C. Harms, S. N. Neal, J. K. Kirkland, M. C. Martin, C. J. Won, M. B. Raschke, S.-W. Cheong, C. J. Fennie, G. L. Carr, H. A. Bechtel, J. L. Musfeldt
Published 2019-11-01

The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling

by Eui Jung Moon, Stephano S. Mello, Caiyun G. Li, Jen-Tsan Chi, Kaushik Thakkar, Jacob G. Kirkland, Edward L. Lagory, Ik Jae Lee, Anh N. Diep, Yu Miao, Marjan Rafat, Marta Vilalta, Laura Castellini, Adam J. Krieg, Edward E. Graves, Laura D. Attardi, Amato J. Giaccia
Published 2021-07-01

Characterization of Virulent West Nile Virus Kunjin Strain, Australia, 2011

by Melinda J. Frost, Jing Zhang, Judith H. Edmonds, Natalie A. Prow, Xingnian Gu, Rodney Davis, Christine Hornitzky, Kathleen E. Arzey, Deborah Finlaison, Paul Hick, Andrew Read, Jody Hobson-Peters, Fiona J. May, Stephen L. Doggett, John Haniotis, Richard C. Russell, Roy A. Hall, Alexander A. Khromykh, Peter D. Kirkland
Published 2012-05-01

Focal Management of Large Brain Metastases and Risk of Leptomeningeal Disease

by Samuel R. Marcrom, MD, Paul M. Foreman, MD, Tyler B. Colvin, BS, Andrew M. McDonald, MD, MS, Robert S. Kirkland, MD, Richard A. Popple, PhD, Kristen O. Riley, MD, James M. Markert, MD, MPH, Christopher D. Willey, MD, PhD, Markus Bredel, MD, PhD, John B. Fiveash, MD
Published 2020-01-01

Identification of HSP90 inhibitors as a novel class of senolytics

by Heike Fuhrmann-Stroissnigg, Yuan Yuan Ling, Jing Zhao, Sara J. McGowan, Yi Zhu, Robert W. Brooks, Diego Grassi, Siobhan Q. Gregg, Jennifer L. Stripay, Akaitz Dorronsoro, Lana Corbo, Priscilla Tang, Christina Bukata, Nadja Ring, Mauro Giacca, Xuesen Li, Tamara Tchkonia, James L. Kirkland, Laura J. Niedernhofer, Paul D. Robbins
Published 2017-09-01

Cellular senescence drives age-dependent hepatic steatosis

by Mikolaj Ogrodnik, Satomi Miwa, Tamar Tchkonia, Dina Tiniakos, Caroline L. Wilson, Albert Lahat, Christoper P. Day, Alastair Burt, Allyson Palmer, Quentin M. Anstee, Sushma Nagaraja Grellscheid, Jan H J. Hoeijmakers, Sander Barnhoorn, Derek A. Mann, Thomas G. Bird, Wilbert P. Vermeij, James L. Kirkland, João F. Passos, Thomas von Zglinicki, Diana Jurk
Published 2017-06-01

Interventions and strategies involving primary healthcare professionals to manage emergency department overcrowding: a scoping review

by Brian H Rowe, Maya M Jeyaraman, Ahmed M Abou-Setta, Leslie Copstein, Ryan Zarychanski, Carolyn Shimmin, Nicole Askin, Rasheda Rabbani, Scott W Kirkland, Malcolm B Doupe, Alecs Chochinov, Gayle Halas, Nameer Al-Yousif, Rachel N Alder, Yahya Al-Yousif, Roger Suss, Jean Mireault, Patrick Tardif, Tamara Buchel, Thomas Beaudry, Melissa Hartwell, William Sevcik
Published 2021-06-01

Functional and epigenetic phenotypes of humans and mice with DNMT3A Overgrowth Syndrome

by Amanda M. Smith, Taylor A. LaValle, Marwan Shinawi, Sai M. Ramakrishnan, Haley J. Abel, Cheryl A. Hill, Nicole M. Kirkland, Michael P. Rettig, Nichole M. Helton, Sharon E. Heath, Francesca Ferraro, David Y. Chen, Sangeeta Adak, Clay F. Semenkovich, Diana L. Christian, Jenna R. Martin, Harrison W. Gabel, Christopher A. Miller, Timothy J. Ley
Published 2021-07-01

Emerging Viral Diseases of Southeast Asia and the Western Pacific

by J.S. Mackenzie, K.B. Chua, P.W. Daniels, B.T. Eaton, H.E. Field, R.A. Hall, K. Halpin, C.A. Johansen, P.D. Kirkland, S.K. Lam, P. McMinn, D.J. Nisbet, R. Paru, A.T. Pyke, S.A. Ritchie, P. Siba, D.W. Smith, G.A. Smith, A.F. van den Hurk, L.F. Wang, D.T. Williams
Published 2001-06-01

Virulence and Evolution of West Nile Virus, Australia, 1960–2012

by Natalie A. Prow, Judith H. Edmonds, David T. Williams, Yin X. Setoh, Helle Bielefeldt-Ohmann, Willy W. Suen, Jody Hobson-Peters, Andrew F. van den Hurk, Alyssa T. Pyke, Sonja Hall-Mendelin, Judith A. Northill, Cheryl A. Johansen, David Warrilow, Jianning Wang, Peter D. Kirkland, Stephen Doggett, Christy C. Andrade, Aaron C. Brault, Alexander A. Khromykh, Roy A. Hall
Published 2016-08-01

IRF2 is a master regulator of human keratinocyte stem cell fate

by Nicolas Mercado, Gabi Schutzius, Christian Kolter, David Estoppey, Sebastian Bergling, Guglielmo Roma, Caroline Gubser Keller, Florian Nigsch, Adrian Salathe, Remi Terranova, John Reece-Hoyes, John Alford, Carsten Russ, Judith Knehr, Dominic Hoepfner, Alexandra Aebi, Heinz Ruffner, Tanner C. Beck, Sajjeev Jagannathan, Calla M. Olson, Hadley E. Sheppard, Selma Z. Elsarrag, Tewis Bouwmeester, Mathias Frederiksen, Felix Lohmann, Charles Y. Lin, Susan Kirkland
Published 2019-10-01

Cellular senescence mediates fibrotic pulmonary disease

by Marissa J. Schafer, Thomas A. White, Koji Iijima, Andrew J. Haak, Giovanni Ligresti, Elizabeth J. Atkinson, Ann L. Oberg, Jodie Birch, Hanna Salmonowicz, Yi Zhu, Daniel L. Mazula, Robert W. Brooks, Heike Fuhrmann-Stroissnigg, Tamar Pirtskhalava, Y. S. Prakash, Tamara Tchkonia, Paul D. Robbins, Marie Christine Aubry, João F. Passos, James L. Kirkland, Daniel J. Tschumperlin, Hirohito Kita, Nathan K. LeBrasseur
Published 2017-02-01

Fisetin is a senotherapeutic that extends health and lifespanResearch in Context

by Matthew J. Yousefzadeh, Yi Zhu, Sara J. McGowan, Luise Angelini, Heike Fuhrmann-Stroissnigg, Ming Xu, Yuan Yuan Ling, Kendra I. Melos, Tamar Pirtskhalava, Christina L. Inman, Collin McGuckian, Erin A. Wade, Jonathon I. Kato, Diego Grassi, Mark Wentworth, Christin E. Burd, Edgar A. Arriaga, Warren L. Ladiges, Tamara Tchkonia, James L. Kirkland, Paul D. Robbins, Laura J. Niedernhofer
Published 2018-10-01

GPR40 partial agonists and AgoPAMs: Differentiating effects on glucose and hormonal secretions in the rodent.

by Michele J Pachanski, Melissa E Kirkland, Daniel T Kosinski, Joel Mane, Boonlert Cheewatrakoolpong, Jiyan Xue, Daphne Szeto, Gail Forrest, Corin Miller, Michelle Bunzel, Christopher W Plummer, Harry R Chobanian, Michael W Miller, Sarah Souza, Brande S Thomas-Fowlkes, Aimie M Ogawa, Adam B Weinglass, Jerry Di Salvo, Xiaoyan Li, Yue Feng, Daniel A Tatosian, Andrew D Howard, Steven L Colletti, Maria E Trujillo
Published 2017-01-01

Health Science Community Will Miss This Bright and Uniting Star: In Memory of Professor Gjumrakch Aliev, M.D, Ph.D.

by Vladimir N. Chubarev, Narasimha M. Beeraka, Mikhail Y. Sinelnikov, Kirill V. Bulygin, Vladimir N. Nikolenko, Elizaveta Mihaylenko, Vadim V. Tarasov, Liudmila M. Mikhaleva, Palmiro Poltronieri, Vijaya Padma Viswanadha, Siva G. Somasundaram, Cecil E. Kirkland, Kuo Chen, Junqi Liu, Ruitai Fan, Mohammad Amjad Kamal, Alexander A. Mironov, SubbaRao V. Madhunapantula, Etheresia Pretorius, Sergey V. Dindyaev, Cristian Muresanu, Olga A. Sukocheva
Published 2021-04-01

Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice

by Andrea Stojakovic, Sergey Trushin, Anthony Sheu, Layla Khalili, Su-Youne Chang, Xing Li, Trace Christensen, Jeffrey L. Salisbury, Rachel E. Geroux, Benjamin Gateno, Padraig J. Flannery, Mrunal Dehankar, Cory C. Funk, Jordan Wilkins, Anna Stepanova, Tara O’Hagan, Alexander Galkin, Jarred Nesbitt, Xiujuan Zhu, Utkarsh Tripathi, Slobodan Macura, Tamar Tchkonia, Tamar Pirtskhalava, James L. Kirkland, Rachel A. Kudgus, Renee A. Schoon, Joel M. Reid, Yu Yamazaki, Takahisa Kanekiyo, Song Zhang, Emirhan Nemutlu, Petras Dzeja, Adam Jaspersen, Ye In Christopher Kwon, Michael K. Lee, Eugenia Trushina
Published 2021-01-01