Epigenetic heterogeneity in cancer

by Mingzhou Guo, Yaojun Peng, Aiai Gao, Chen Du, James G. Herman
Published 2019-10-01

Retinoic acid-induced 2 (RAI2) is a novel tumor suppressor, and promoter region methylation of RAI2 is a poor prognostic marker in colorectal cancer

by Wenji Yan, Kongming Wu, James G. Herman, Xiuduan Xu, Yunsheng Yang, Guanghai Dai, Mingzhou Guo
Published 2018-05-01

Epigenetic silencing of TMEM176A activates ERK signaling in human hepatocellular carcinoma

by Hongxia Li, Meiying Zhang, Enqiang Linghu, Fuyou Zhou, James G. Herman, Liming Hu, Mingzhou Guo
Published 2018-11-01

Methylation of DACT2 promotes papillary thyroid cancer metastasis by activating Wnt signaling.

by Zhiyan Zhao, James G Herman, Malcolm V Brock, Jindong Sheng, Meiying Zhang, Baoguo Liu, Mingzhou Guo
Published 2014-01-01

DNA Methylation at the Novel CpG Sites in the Promoter of MED15/PCQAP Gene as a Biomarker for Head and Neck Cancers

by Dmitry A. Ovchinnikov, Yunxia Wan, William B. Coman, Pratibala Pandit, Justin J. Cooper-White, James G. Herman, Chamindie Punyadeera
Published 2014-07-01

DNA Methylation at the Novel CpG Sites in the Promoter of / Gene as a Biomarker for Head and Neck Cancers

by Dmitry A. Ovchinnikov, Yunxia Wan, William B. Coman, Pratibala Pandit, Justin J. Cooper-White, James G. Herman, Chamindie Punyadeera
Published 2014-01-01

Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth

by Yuzhu Wang, Tao He, James G. Herman, Enqiang Linghu, Yunsheng Yang, François Fuks, Fuyou Zhou, Linjie Song, Mingzhou Guo
Published 2017-10-01

Correction to: Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth

by Yuzhu Wang, Tao He, James G. Herman, Enqiang Linghu, Yunsheng Yang, François Fuks, Fuyou Zhou, Linjie Song, Mingzhou Guo
Published 2018-03-01

Silencing HOXD10 by promoter region hypermethylation activates ERK signaling in hepatocellular carcinoma

by Yulin Guo, Yaojun Peng, Dan Gao, Meiying Zhang, Weili Yang, Enqiang Linghu, James G. Herman, François Fuks, Guanglong Dong, Mingzhou Guo
Published 2017-10-01

PcG proteins, DNA methylation, and gene repression by chromatin looping.

by Vijay K Tiwari, Kelly M McGarvey, Julien D F Licchesi, Joyce E Ohm, James G Herman, Dirk Schübeler, Stephen B Baylin
Published 2008-12-01

Methylation-Specific PCR Unraveled

by Sarah Derks, Marjolein H. F. M. Lentjes, Debby M. E. I. Hellebrekers, Adriaan P. de Bruïne, James G. Herman, Manon van Engeland
Published 2004-01-01

Silencing DACH1 promotes esophageal cancer growth by inhibiting TGF-β signaling.

by Liang Wu, James G Herman, Malcolm V Brock, Kongming Wu, Gaoping Mao, Wenji Yan, Yan Nie, Hao Liang, Qimin Zhan, Wen Li, Mingzhou Guo
Published 2014-01-01

Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation.

by Kevin Pruitt, Rebekah L Zinn, Joyce E Ohm, Kelly M McGarvey, Sung-Hae L Kang, D Neil Watkins, James G Herman, Stephen B Baylin
Published 2006-03-01

Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis.

by Timothy A Chan, Sabine Glockner, Joo Mi Yi, Wei Chen, Leander Van Neste, Leslie Cope, James G Herman, Victor Velculescu, Kornel E Schuebel, Nita Ahuja, Stephen B Baylin
Published 2008-05-01

Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer.

by Anju Singh, Vikas Misra, Rajesh K Thimmulappa, Hannah Lee, Stephen Ames, Mohammad O Hoque, James G Herman, Stephen B Baylin, David Sidransky, Edward Gabrielson, Malcolm V Brock, Shyam Biswal
Published 2006-10-01

Promoter Methylation Precedes Chromosomal Alterations in Colorectal Cancer Development

by Sarah Derks, Cindy Postma, Peter T. M. Moerkerk, Sandra M. van den Bosch, Beatriz Carvalho, Mario A. J. A. Hermsen, Walter Giaretti, James G. Herman, Matty P. Weijenberg, Adriaan P. de Bruïne, Gerrit A. Meijer, Manon van Engeland
Published 2006-01-01

Early life exposure to famine and colorectal cancer risk: a role for epigenetic mechanisms.

by Laura A E Hughes, Piet A van den Brandt, Adriaan P de Bruïne, Kim A D Wouters, Sarah Hulsmans, Angela Spiertz, R Alexandra Goldbohm, Anton F P M de Goeij, James G Herman, Matty P Weijenberg, Manon van Engeland
Published 2009-11-01

A phase 2 trial of gemcitabine and docetaxel in patients with metastatic colorectal adenocarcinoma with methylated checkpoint with forkhead and ring finger domain promoter and/or m...

by Marina Baretti, Enusha Karunasena, Marianna Zahurak, Rosalind Walker, Yang Zhao, Thomas R. Pisanic 2nd, Tza‐Huei Wang, Tim F. Greten, Austin G. Duffy, Elske Gootjes, Gerrit Meijer, Henk M.W. Verheul, Nita Ahuja, James G. Herman, Nilofer S. Azad
Published 2021-05-01

Comparing the DNA hypermethylome with gene mutations in human colorectal cancer.

by Kornel E Schuebel, Wei Chen, Leslie Cope, Sabine C Glöckner, Hiromu Suzuki, Joo-Mi Yi, Timothy A Chan, Leander Van Neste, Wim Van Criekinge, Sandra van den Bosch, Manon van Engeland, Angela H Ting, Kamwing Jair, Wayne Yu, Minoru Toyota, Kohzoh Imai, Nita Ahuja, James G Herman, Stephen B Baylin
Published 2007-09-01