Chemical Synthesis, Proper Folding, Na_v Channel Selectivity Profile and Analgesic Properties of the Spider Peptide Phlotoxin 1

by Sébastien Nicolas, Claude Zoukimian, Frank Bosmans, Jérôme Montnach, Sylvie Diochot, Eva Cuypers, Stephan De Waard, Rémy Béroud, Dietrich Mebs, David Craik, Didier Boturyn, Michel Lazdunski, Jan Tytgat, Michel De Waard
Published 2019-06-01

Birt-Hogg-Dubé Syndrome and Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome: An Effective Multidisciplinary Approach to Hereditary Renal Cancer Predisposing Syndromes

by Mohammad Al-Shinnag, Mohammad Al-Shinnag, Helen Marfan, Helen Marfan, Rachel Susman, Rachel Susman, Jan Wakeling, Sonja Gustafson, Sonja Gustafson, Simon Wood, Simon Wood, Andrew John Mallett, Andrew John Mallett, Andrew John Mallett, Andrew John Mallett
Published 2021-09-01

Genetic evidence for a large overlap and potential bidirectional causal effects between resilience and well-being

by Lianne P. de Vries, Bart M.L. Baselmans, Jurjen J. Luykx, Eveline L. de Zeeuw, Camelia C. Minică, Eco J.C. de Geus, Christiaan H. Vinkers, Meike Bartels
Published 2021-05-01

Protocol for a case–control study investigating the clinical phenotypes and genetic regulation of endometriosis in Indian women: the ECGRI study

by Shashank Shekhar, Gita Mishra, Grant Montgomery, Rahul K. Gajbhiye, Murlidhar V Pai, Pranay Phukan, Kedar Padte, Pramathes DasMahapatra, Bimal M. John, Chaitanya Shembekar, Aishwarya V. Bhurke, Nilajkumar Bagde, Ketki Kulkarni, Nagendra Sardeshpande, Anil Humane, Swati Mahobia, Millind Shah, Uma Singh, Aarti Srivastava, Neeta Warty, Sunita Chandra, Smita D. Mahale
Published 2021-08-01

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

by Darina Czamara, Gökçen Eraslan, Christian M. Page, Jari Lahti, Marius Lahti-Pulkkinen, Esa Hämäläinen, Eero Kajantie, Hannele Laivuori, Pia M. Villa, Rebecca M. Reynolds, Wenche Nystad, Siri E. Håberg, Stephanie J. London, Kieran J. O’Donnell, Elika Garg, Michael J. Meaney, Sonja Entringer, Pathik D. Wadhwa, Claudia Buss, Meaghan J. Jones, David T. S. Lin, Julie L. MacIsaac, Michael S. Kobor, Nastassja Koen, Heather J. Zar, Karestan C. Koenen, Shareefa Dalvie, Dan J. Stein, Ivan Kondofersky, Nikola S. Müller, Fabian J. Theis, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Katri Räikkönen, Elisabeth B. Binder
Published 2019-06-01

Curcuma longa rhizome extract and Curcumin reduce the adhesion of Acanthamoeba triangularis trophozoites and cysts in polystyrene plastic surface and contact lens

by Watcharapong Mitsuwan, Suthinee Sangkanu, Chonticha Romyasamit, Chalermpon Kaewjai, Tajudeen O. Jimoh, Maria de Lourdes Pereira, Abolghasem Siyadatpanah, Sunil Kayesth, Muhammad Nawaz, Mohammed Rahmatullah, Mark S. Butler, Polrat Wilairatana, Christophe Wiart, Veeranoot Nissapatorn
Published 2020-12-01

Genomic Signatures After Five Generations of Intensive Selective Breeding: Runs of Homozygosity and Genetic Diversity in Representative Domestic and Wild Populations of Turbot (Sco...

by Oscar Aramburu, Oscar Aramburu, Francisco Ceballos, Adrián Casanova, Adrián Casanova, Alan Le Moan, Jakob Hemmer-Hansen, Dorte Bekkevold, Carmen Bouza, Carmen Bouza, Paulino Martínez, Paulino Martínez
Published 2020-04-01

A Pragmatic Approach Identifies a High Rate of Nonalcoholic Fatty Liver Disease With Advanced Fibrosis in Diabetes Clinics and At‐Risk Populations in Primary Care

by PreyaJanubhai Patel, Fabrina Hossain, Leigh Ula Horsfall, Xuan Banh, Kelly Lee Hayward, Suzanne Williams, Tracey Johnson, Anne Bernard, Nigel Neil Brown, Guy Lampe, Lyndall Buck, Nivene Saad, Anthony William Russell, Patricia Casarolli Valery, Katharine Margaret Irvine, Andrew Donald Clouston, Katherine Anne Stuart, William Rosenberg, Elizabeth Ellen Powell
Published 2018-08-01

No association between ACTN3 R577X and ACE I/D polymorphisms and endurance running times in 698 Caucasian athletes

by Ioannis D. Papadimitriou, Sarah J. Lockey, Sarah Voisin, Adam J. Herbert, Fleur Garton, Peter J. Houweling, Pawel Cieszczyk, Agnieszka Maciejewska-Skrendo, Marek Sawczuk, Myosotis Massidda, Carla Maria Calò, Irina V. Astratenkova, Anastasia Kouvatsi, Anastasiya M. Druzhevskaya, Macsue Jacques, Ildus I. Ahmetov, Georgina K. Stebbings, Shane Heffernan, Stephen H. Day, Robert Erskine, Charles Pedlar, Courtney Kipps, Kathryn N. North, Alun G. Williams, Nir Eynon
Published 2018-01-01

Genome sequencing in persistently unsolved white matter disorders

by Guy Helman, Bryan R. Lajoie, Joanna Crawford, Asako Takanohashi, Marzena Walkiewicz, Egor Dolzhenko, Andrew M. Gross, Vladimir G. Gainullin, Stephen J. Bent, Emma M. Jenkinson, Sacha Ferdinandusse, Hans R. Waterham, Imen Dorboz, Enrico Bertini, Noriko Miyake, Nicole I. Wolf, Truus E. M. Abbink, Susan M. Kirwin, Christina M. Tan, Grace M. Hobson, Long Guo, Shiro Ikegawa, Amy Pizzino, Johanna L. Schmidt, Genevieve Bernard, Raphael Schiffmann, Marjo S. van derKnaap, Cas Simons, Ryan J. Taft, Adeline Vanderver
Published 2020-01-01

Using Monozygotic Twins to Dissect Common Genes in Posttraumatic Stress Disorder and Migraine

by Charlotte K. Bainomugisa, Heidi G. Sutherland, Heidi G. Sutherland, Richard Parker, Allan F. Mcrae, Larisa M. Haupt, Larisa M. Haupt, Lyn R. Griffiths, Lyn R. Griffiths, Andrew Heath, Elliot C. Nelson, Margaret J. Wright, Margaret J. Wright, Ian B. Hickie, Nicholas G. Martin, Dale R. Nyholt, Divya Mehta
Published 2021-06-01

Case Report: Identification of Novel Variants in ERCC4 and DDB2 Genes in Two Tunisian Patients With Atypical Xeroderma Pigmentosum Phenotype

by Imen Nabouli, Asma Chikhaoui, Houcemeddine Othman, Sahar Elouej, Sahar Elouej, Meriem Jones, Meriem Jones, Arnaud Lagarde, Meriem Ben Rekaya, Olfa Messaoud, Mohamed Zghal, Valerie Delague, Nicolas Levy, Nicolas Levy, Annachiara De Sandre-Giovannoli, Annachiara De Sandre-Giovannoli, Sonia Abdelhak, Houda Yacoub-Youssef
Published 2021-05-01

Defective NET clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation

by Hanna Englert, Chandini Rangaswamy, Carsten Deppermann, Jan-Peter Sperhake, Christoph Krisp, Danny Schreier, Emma Gordon, Sandra Konrath, Munif Haddad, Giordano Pula, Reiner K. Mailer, Hartmut Schlüter, Stefan Kluge, Florian Langer, Klaus Püschel, Kosta Panousis, Evi X. Stavrou, Coen Maas, Thomas Renné, Maike Frye
Published 2021-05-01

Genetic association study of childhood aggression across raters, instruments, and age

by Hill F. Ip, Camiel M. van der Laan, Eva M. L. Krapohl, Isabell Brikell, Cristina Sánchez-Mora, Ilja M. Nolte, Beate St Pourcain, Koen Bolhuis, Teemu Palviainen, Hadi Zafarmand, Lucía Colodro-Conde, Scott Gordon, Tetyana Zayats, Fazil Aliev, Chang Jiang, Carol A. Wang, Gretchen Saunders, Ville Karhunen, Anke R. Hammerschlag, Daniel E. Adkins, Richard Border, Roseann E. Peterson, Joseph A. Prinz, Elisabeth Thiering, Ilkka Seppälä, Natàlia Vilor-Tejedor, Tarunveer S. Ahluwalia, Felix R. Day, Jouke-Jan Hottenga, Andrea G. Allegrini, Kaili Rimfeld, Qi Chen, Yi Lu, Joanna Martin, María Soler Artigas, Paula Rovira, Rosa Bosch, Gemma Español, Josep Antoni Ramos Quiroga, Alexander Neumann, Judith Ensink, Katrina Grasby, José J. Morosoli, Xiaoran Tong, Shelby Marrington, Christel Middeldorp, James G. Scott, Anna Vinkhuyzen, Andrey A. Shabalin, Robin Corley, Luke M. Evans, Karen Sugden, Silvia Alemany, Lærke Sass, Rebecca Vinding, Kate Ruth, Jess Tyrrell, Gareth E. Davies, Erik A. Ehli, Fiona A. Hagenbeek, Eveline De Zeeuw, Toos C.E.M. Van Beijsterveldt, Henrik Larsson, Harold Snieder, Frank C. Verhulst, Najaf Amin, Alyce M. Whipp, Tellervo Korhonen, Eero Vuoksimaa, Richard J. Rose, André G. Uitterlinden, Andrew C. Heath, Pamela Madden, Jan Haavik, Jennifer R. Harris, Øyvind Helgeland, Stefan Johansson, Gun Peggy S. Knudsen, Pal Rasmus Njolstad, Qing Lu, Alina Rodriguez, Anjali K. Henders, Abdullah Mamun, Jackob M. Najman, Sandy Brown, Christian Hopfer, Kenneth Krauter, Chandra Reynolds, Andrew Smolen, Michael Stallings, Sally Wadsworth, Tamara L. Wall, Judy L. Silberg, Allison Miller, Liisa Keltikangas-Järvinen, Christian Hakulinen, Laura Pulkki-Råback, Alexandra Havdahl, Per Magnus, Olli T. Raitakari, John R. B. Perry, Sabrina Llop, Maria-Jose Lopez-Espinosa, Klaus Bønnelykke, Hans Bisgaard, Jordi Sunyer, Terho Lehtimäki, Louise Arseneault, Marie Standl, Joachim Heinrich, Joseph Boden, John Pearson, L. John Horwood, Martin Kennedy, Richie Poulton, Lindon J. Eaves, Hermine H. Maes, John Hewitt, William E. Copeland, Elizabeth J. Costello, Gail M. Williams, Naomi Wray, Marjo-Riitta Järvelin, Matt McGue, William Iacono, Avshalom Caspi, Terrie E. Moffitt, Andrew Whitehouse, Craig E. Pennell, Kelly L. Klump, S. Alexandra Burt, Danielle M. Dick, Ted Reichborn-Kjennerud, Nicholas G. Martin, Sarah E. Medland, Tanja Vrijkotte, Jaakko Kaprio, Henning Tiemeier, George Davey Smith, Catharina A. Hartman, Albertine J. Oldehinkel, Miquel Casas, Marta Ribasés, Paul Lichtenstein, Sebastian Lundström, Robert Plomin, Meike Bartels, Michel G. Nivard, Dorret I. Boomsma
Published 2021-07-01

Poor cardiovascular health is associated with subclinical atherosclerosis in apparently healthy sub-Saharan African populations: an H3Africa AWI-Gen study

by Engelbert A. Nonterah, Nigel J. Crowther, Abraham Oduro, Godfred Agongo, Lisa K. Micklesfield, Palwendé R. Boua, Solomon S. R. Choma, Shukri F. Mohamed, Herman Sorgho, Stephen M. Tollman, Shane A. Norris, Frederick J. Raal, Diederick E. Grobbee, Michelé Ramsay, Michiel L. Bots, Kerstin Klipstein-Grobusch, as part of the H3Africa AWI-Gen study
Published 2021-02-01

Adar3 Is Involved in Learning and Memory in Mice

by Dessislava Mladenova, Dessislava Mladenova, Guy Barry, Guy Barry, Lyndsey M. Konen, Lyndsey M. Konen, Lyndsey M. Konen, Sandy S. Pineda, Sandy S. Pineda, Boris Guennewig, Boris Guennewig, Lotta Avesson, Raphael Zinn, Raphael Zinn, Raphael Zinn, Nicole Schonrock, Nicole Schonrock, Maina Bitar, Maina Bitar, Nicky Jonkhout, Nicky Jonkhout, Lauren Crumlish, Dominik C. Kaczorowski, Andrew Gong, Mark Pinese, Mark Pinese, Gloria R. Franco, Carl R. Walkley, Bryce Vissel, Bryce Vissel, Bryce Vissel, John S. Mattick, John S. Mattick
Published 2018-04-01

Identification of Novel BRCA1 and RAD50 Mutations Associated With Breast Cancer Predisposition in Tunisian Patients

by Najah Mighri, Yosr Hamdi, Maroua Boujemaa, Houcemeddine Othman, Sonia Ben Nasr, Sonia Ben Nasr, Houda El Benna, Nesrine Mejri, Nesrine Mejri, Soumaya Labidi, Soumaya Labidi, Jihen Ayari, Jihen Ayari, Olfa Jaidene, Hanen Bouaziz, Mariem Ben Rekaya, Ridha M’rad, Abderrazek Haddaoui, Khaled Rahal, Hamouda Boussen, Hamouda Boussen, Samir Boubaker, Sonia Abdelhak
Published 2020-11-01

Ensemble Learning of Convolutional Neural Network, Support Vector Machine, and Best Linear Unbiased Predictor for Brain Age Prediction: ARAMIS Contribution to the Predictive Analyt...

by Baptiste Couvy-Duchesne, Baptiste Couvy-Duchesne, Baptiste Couvy-Duchesne, Baptiste Couvy-Duchesne, Baptiste Couvy-Duchesne, Baptiste Couvy-Duchesne, Johann Faouzi, Johann Faouzi, Johann Faouzi, Johann Faouzi, Johann Faouzi, Benoît Martin, Benoît Martin, Benoît Martin, Benoît Martin, Benoît Martin, Elina Thibeau–Sutre, Elina Thibeau–Sutre, Elina Thibeau–Sutre, Elina Thibeau–Sutre, Elina Thibeau–Sutre, Adam Wild, Adam Wild, Adam Wild, Adam Wild, Adam Wild, Manon Ansart, Manon Ansart, Manon Ansart, Manon Ansart, Manon Ansart, Stanley Durrleman, Stanley Durrleman, Stanley Durrleman, Stanley Durrleman, Stanley Durrleman, Didier Dormont, Didier Dormont, Didier Dormont, Didier Dormont, Didier Dormont, Didier Dormont, Ninon Burgos, Ninon Burgos, Ninon Burgos, Ninon Burgos, Ninon Burgos, Olivier Colliot, Olivier Colliot, Olivier Colliot, Olivier Colliot, Olivier Colliot
Published 2020-12-01

Recessive mutations in ATP8A2 cause severe hypotonia, cognitive impairment, hyperkinetic movement disorders and progressive optic atrophy

by Hugh J. McMillan, Aida Telegrafi, Amanda Singleton, Megan T. Cho, Daniel Lelli, Francis C. Lynn, Julie Griffin, Alexander Asamoah, Tuula Rinne, Corrie E. Erasmus, David A. Koolen, Charlotte A. Haaxma, Boris Keren, Diane Doummar, Cyril Mignot, Islay Thompson, Lea Velsher, Mohammadreza Dehghani, Mohammad Yahya Vahidi Mehrjardi, Reza Maroofian, Michel Tchan, Cas Simons, John Christodoulou, Elena Martín-Hernández, Maria J. Guillen Sacoto, Lindsay B. Henderson, Heather McLaughlin, Laurie L. Molday, Robert S. Molday, Grace Yoon
Published 2018-05-01

Epigenetic signatures of starting and stopping smokingResearch in context

by Daniel L. McCartney, Anna J. Stevenson, Robert F. Hillary, Rosie M. Walker, Mairead L. Bermingham, Stewart W. Morris, Toni-Kim Clarke, Archie Campbell, Alison D. Murray, Heather C. Whalley, David J. Porteous, Peter M. Visscher, Andrew M. McIntosh, Kathryn L. Evans, Ian J. Deary, Riccardo E. Marioni
Published 2018-11-01