POPIA Code of Conduct for Research

by Rachel Adams, Fola Adeleke, Dominique Anderson, Ahmed Bawa, Nicola Branson, Alan Christoffels, Jantina de Vries, Harriet Etheredge, Eleni Flack-Davison, Mark Gaffley, Monique Marks, Mongezi Mdhluli, Safia Mahomed, Mapitso Molefe, Tshilidzi Muthivhi, Caroline Ncube, Antonel Olckers, Maria Papathanasopoulos, Jane Pillay, Tobias Schonwetter, Jerome Singh, Carmen Swanepoel, Michèle Ramsay
Published 2021-05-01

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

by Sonia Shah, Albert Henry, Carolina Roselli, Honghuang Lin, Garðar Sveinbjörnsson, Ghazaleh Fatemifar, Åsa K. Hedman, Jemma B. Wilk, Michael P. Morley, Mark D. Chaffin, Anna Helgadottir, Niek Verweij, Abbas Dehghan, Peter Almgren, Charlotte Andersson, Krishna G. Aragam, Johan Ärnlöv, Joshua D. Backman, Mary L. Biggs, Heather L. Bloom, Jeffrey Brandimarto, Michael R. Brown, Leonard Buckbinder, David J. Carey, Daniel I. Chasman, Xing Chen, Xu Chen, Jonathan Chung, William Chutkow, James P. Cook, Graciela E. Delgado, Spiros Denaxas, Alexander S. Doney, Marcus Dörr, Samuel C. Dudley, Michael E. Dunn, Gunnar Engström, Tõnu Esko, Stephan B. Felix, Chris Finan, Ian Ford, Mohsen Ghanbari, Sahar Ghasemi, Vilmantas Giedraitis, Franco Giulianini, John S. Gottdiener, Stefan Gross, Daníel F. Guðbjartsson, Rebecca Gutmann, Christopher M. Haggerty, Pim van der Harst, Craig L. Hyde, Erik Ingelsson, J. Wouter Jukema, Maryam Kavousi, Kay-Tee Khaw, Marcus E. Kleber, Lars Køber, Andrea Koekemoer, Claudia Langenberg, Lars Lind, Cecilia M. Lindgren, Barry London, Luca A. Lotta, Ruth C. Lovering, Jian’an Luan, Patrik Magnusson, Anubha Mahajan, Kenneth B. Margulies, Winfried März, Olle Melander, Ify R. Mordi, Thomas Morgan, Andrew D. Morris, Andrew P. Morris, Alanna C. Morrison, Michael W. Nagle, Christopher P. Nelson, Alexander Niessner, Teemu Niiranen, Michelle L. O’Donoghue, Anjali T. Owens, Colin N. A. Palmer, Helen M. Parry, Markus Perola, Eliana Portilla-Fernandez, Bruce M. Psaty, Regeneron Genetics Center, Kenneth M. Rice, Paul M. Ridker, Simon P. R. Romaine, Jerome I. Rotter, Perttu Salo, Veikko Salomaa, Jessica van Setten, Alaa A. Shalaby, Diane T. Smelser, Nicholas L. Smith, Steen Stender, David J. Stott, Per Svensson, Mari-Liis Tammesoo, Kent D. Taylor, Maris Teder-Laving, Alexander Teumer, Guðmundur Thorgeirsson, Unnur Thorsteinsdottir, Christian Torp-Pedersen, Stella Trompet, Benoit Tyl, Andre G. Uitterlinden, Abirami Veluchamy, Uwe Völker, Adriaan A. Voors, Xiaosong Wang, Nicholas J. Wareham, Dawn Waterworth, Peter E. Weeke, Raul Weiss, Kerri L. Wiggins, Heming Xing, Laura M. Yerges-Armstrong, Bing Yu, Faiez Zannad, Jing Hua Zhao, Harry Hemingway, Nilesh J. Samani, John J. V. McMurray, Jian Yang, Peter M. Visscher, Christopher Newton-Cheh, Anders Malarstig, Hilma Holm, Steven A. Lubitz, Naveed Sattar, Michael V. Holmes, Thomas P. Cappola, Folkert W. Asselbergs, Aroon D. Hingorani, Karoline Kuchenbaecker, Patrick T. Ellinor, Chim C. Lang, Kari Stefansson, J. Gustav Smith, Ramachandran S. Vasan, Daniel I. Swerdlow, R. Thomas Lumbers
Published 2020-01-01

Sickle Cell Disease Genomics of Africa (SickleGenAfrica) Network: ethical framework and initial qualitative findings from community engagement in Ghana, Nigeria and Tanzania

by Mahmoud U Sani, David Nana Adjei, Nicola Mulder, Gordon Awandare, Vivian Paintsil, Obiageli Nnodu, Jonathan Stiles, Kofi A Anie, Solomon Fiifi Ofori-Acquah, Julie Makani, Edeghonghon Olayemi, Titilope Adenike Adeyemo, Najibah Aliyu Galadanci, Furahini Tluway, Peter Mensah, Joseph Sarfo-Antwi, Henry Nwokobia, Awwal Gambo, Adebola Benjamin, Arafa Salim, Judith A Osae-Larbi, Amma Benneh-Akwasi Kuma, Anita Ghansah, Catherine Segbefia, Solomon F Ofori-Acquah, William Kudzi, Vivian Painstil, Aisha Kuliya-Gwarzo, Adullahi Shehu, Baba Musa, Mahmoud Sani, Najibah Aliyu Galandanci, Alashle Abimiku, Ameh Adeyefa, Obiageli E. Nnodu, Michael Akinsete, Olufunto Kalejaiye, Titilope Adeyemo, Flora Ndobho, Josephine Mgaya, Siana Nkya, Flordeliza Villanueva, Samit Ghosh, Solomon Ofori-Acquah, Ryan Minster
Published 2021-07-01

Estimating the burden of cardiovascular risk in community dwellers over 40 years old in South Africa, Kenya, Burkina Faso and Ghana

by Lisa K Micklesfield, Ryan G Wagner, Shukri F Mohamed, Nigel J Crowther, Palwende Romauld Boua, Engelbert A Nonterah, Felistas Mashinya, Michèle Ramsay
Published 2021-01-01

Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms

by Samuel E. Jones, Jacqueline M. Lane, Andrew R. Wood, Vincent T. van Hees, Jessica Tyrrell, Robin N. Beaumont, Aaron R. Jeffries, Hassan S. Dashti, Melvyn Hillsdon, Katherine S. Ruth, Marcus A. Tuke, Hanieh Yaghootkar, Seth A. Sharp, Yingjie Jie, William D. Thompson, Jamie W. Harrison, Amy Dawes, Enda M. Byrne, Henning Tiemeier, Karla V. Allebrandt, Jack Bowden, David W. Ray, Rachel M. Freathy, Anna Murray, Diego R. Mazzotti, Philip R. Gehrman, Debbie A. Lawlor, Timothy M. Frayling, Martin K. Rutter, David A. Hinds, Richa Saxena, Michael N. Weedon
Published 2019-01-01

Nkx2.5 marks angioblasts that contribute to hemogenic endothelium of the endocardium and dorsal aorta

by Lyad Zamir, Reena Singh, Elisha Nathan, Ralph Patrick, Oren Yifa, Yfat Yahalom-Ronen, Alaa A Arraf, Thomas M Schultheiss, Shengbao Suo, Jing-Dong Jackie Han, Guangdun Peng, Naihe Jing, Yuliang Wang, Nathan Palpant, Patrick PL Tam, Richard P Harvey, Eldad Tzahor
Published 2017-03-01

A Proteome-Wide Immunoinformatics Tool to Accelerate T-Cell Epitope Discovery and Vaccine Design in the Context of Emerging Infectious Diseases: An Ethnicity-Oriented Approach

by Patricio Oyarzun, Manju Kashyap, Victor Fica, Alexis Salas-Burgos, Faviel F. Gonzalez-Galarza, Antony McCabe, Andrew R. Jones, Derek Middleton, Bostjan Kobe
Published 2021-02-01

The Next Generation Scientist program: capacity-building for future scientific leaders in low- and middle-income countries

by Goonaseelan Pillai, Kelly Chibale, Edwin C. Constable, Akiko N. Keller, Marcelo M. Gutierrez, Fareed Mirza, Christian Sengstag, Collen Masimirembwa, Paolo Denti, Gary Maartens, Michèle Ramsay, Bernhards Ogutu, Eyasu Makonnen, Richard Gordon, Carlos Gil Ferreira, Fernando Alberto Goldbaum, Wim M. S. Degrave, Jonathan Spector, Brigitta Tadmor, Hedwig J. Kaiser
Published 2018-10-01

The interplay between host genetics and the gut microbiome reveals common and distinct microbiome features for complex human diseases

by Fengzhe Xu, Yuanqing Fu, Ting-yu Sun, Zengliang Jiang, Zelei Miao, Menglei Shuai, Wanglong Gou, Chu-wen Ling, Jian Yang, Jun Wang, Yu-ming Chen, Ju-Sheng Zheng
Published 2020-10-01

Development of Plant-Produced Recombinant ACE2-Fc Fusion Protein as a Potential Therapeutic Agent Against SARS-CoV-2

by Konlavat Siriwattananon, Konlavat Siriwattananon, Suwimon Manopwisedjaroen, Phongthon Kanjanasirirat, Priyo Budi Purwono, Priyo Budi Purwono, Kaewta Rattanapisit, Kaewta Rattanapisit, Balamurugan Shanmugaraj, Balamurugan Shanmugaraj, Duncan R. Smith, Suparerk Borwornpinyo, Arunee Thitithanyanont, Waranyoo Phoolcharoen, Waranyoo Phoolcharoen
Published 2021-01-01

Genome-Wide SNP Discovery in Indigenous Cattle Breeds of South Africa

by Avhashoni A. Zwane, Avhashoni A. Zwane, Robert D. Schnabel, Robert D. Schnabel, Jesse Hoff, Ananyo Choudhury, Mahlako Linah Makgahlela, Mahlako Linah Makgahlela, Azwihangwisi Maiwashe, Azwihangwisi Maiwashe, Este Van Marle-Koster, Jeremy F. Taylor
Published 2019-03-01

Region-specific sex differences in the hippocampus

by Liza van Eijk, Narelle K. Hansell, Lachlan T. Strike, Baptiste Couvy-Duchesne, Greig I. de Zubicaray, Paul M. Thompson, Katie L. McMahon, Brendan P. Zietsch, Margaret J. Wright
Published 2020-07-01

Study protocol for the Australian autism biobank: an international resource to advance autism discovery research

by Gail A. Alvares, Paul A. Dawson, Cheryl Dissanayake, Valsamma Eapen, Jacob Gratten, Rachel Grove, Anjali Henders, Helen Heussler, Lauren Lawson, Anne Masi, Emma Raymond, Felicity Rose, Leanne Wallace, Naomi R. Wray, Andrew J. O. Whitehouse, the Australian Autism Biobank team
Published 2018-08-01

ORAI1 and ORAI3 in Breast Cancer Molecular Subtypes and the Identification of ORAI3 as a Hypoxia Sensitive Gene and a Regulator of Hypoxia Responses

by Iman Azimi, Michael J.G. Milevskiy, Silke B. Chalmers, Kunsala T.D.S. Yapa, Mélanie Robitaille, Christopher Henry, Gregory J. Baillie, Erik W. Thompson, Sarah J. Roberts-Thomson, Gregory R. Monteith
Published 2019-02-01

Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP

by Amelia T. Soderholm, Timothy C. Barnett, Timothy C. Barnett, Othmar Korn, Tania Rivera-Hernandez, Lisa M. Seymour, Benjamin L. Schulz, Benjamin L. Schulz, Victor Nizet, Christine A. Wells, Matthew J. Sweet, Matthew J. Sweet, Mark J. Walker, Mark J. Walker
Published 2018-05-01

Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma

by Laura A. Genovesi, Amanda Millar, Elissa Tolson, Matthew Singleton, Emily Hassall, Marija Kojic, Caterina Brighi, Emily Girard, Clara Andradas, Mani Kuchibhotla, Dharmesh D. Bhuva, Raelene Endersby, Nicholas G. Gottardo, Anne Bernard, Christelle Adolphe, James M. Olson, Michael D. Taylor, Melissa J. Davis, Brandon J. Wainwright
Published 2021-06-01

Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study

by Yuanqing Fu, Fengzhe Xu, Longda Jiang, Zelei Miao, Xinxiu Liang, Jian Yang, Susanna C. Larsson, Ju-Sheng Zheng
Published 2021-07-01

Influence of the MUC1 Cell Surface Mucin on Gastric Mucosal Gene Expression Profiles in Response to Helicobacter pylori Infection in Mice

by Yong H. Sheng, Garrett Z. Ng, Kim M. Summers, Alison L. Every, Gareth Price, Sumaira Z. Hasnain, Philip Sutton, Philip Sutton, Michael A. McGuckin, Michael A. McGuckin
Published 2020-07-01

Shared Molecular Genetic Mechanisms Underlie Endometriosis and Migraine Comorbidity

by Emmanuel O. Adewuyi, Yadav Sapkota, International Endogene Consortium (IEC), 23andMe Research Team, International Headache Genetics Consortium (IHGC), Asa Auta, Kosuke Yoshihara, Mette Nyegaard, Lyn R. Griffiths, Grant W. Montgomery, Daniel I. Chasman, Dale R. Nyholt
Published 2020-02-01

Salt-Tolerant Antifungal and Antibacterial Activities of the Corn Defensin ZmD32

by Bomai K. Kerenga, James A. McKenna, Peta J. Harvey, Pedro Quimbar, Donovan Garcia-Ceron, Fung T. Lay, Thanh Kha Phan, Prem K. Veneer, Shaily Vasa, Kathy Parisi, Thomas M. A. Shafee, Nicole L. van der Weerden, Mark D. Hulett, David J. Craik, Marilyn A. Anderson, Mark R. Bleackley
Published 2019-04-01