OSCA: a tool for omic-data-based complex trait analysis

by Futao Zhang, Wenhan Chen, Zhihong Zhu, Qian Zhang, Marta F. Nabais, Ting Qi, Ian J. Deary, Naomi R. Wray, Peter M. Visscher, Allan F. McRae, Jian Yang
Published 2019-05-01

The effect of X-linked dosage compensation on complex trait variation

by Julia Sidorenko, Irfahan Kassam, Kathryn E. Kemper, Jian Zeng, Luke R. Lloyd-Jones, Grant W. Montgomery, Greg Gibson, Andres Metspalu, Tonu Esko, Jian Yang, Allan F. McRae, Peter M. Visscher
Published 2019-07-01

Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation

by Vikas A. Tillu, James Rae, Ya Gao, Nicholas Ariotti, Matthias Floetenmeyer, Oleksiy Kovtun, Kerrie-Ann McMahon, Natasha Chaudhary, Robert G. Parton, Brett M. Collins
Published 2021-02-01

Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae

by Yann Gambin, Nicholas Ariotti, Kerrie-Ann McMahon, Michele Bastiani, Emma Sierecki, Oleksiy Kovtun, Mark E Polinkovsky, Astrid Magenau, WooRam Jung, Satomi Okano, Yong Zhou, Natalya Leneva, Sergey Mureev, Wayne Johnston, Katharina Gaus, John F Hancock, Brett M Collins, Kirill Alexandrov, Robert G Parton
Published 2014-01-01

Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease

by Costanza L. Vallerga, Futao Zhang, Javed Fowdar, Allan F. McRae, Ting Qi, Marta F. Nabais, Qian Zhang, Irfahan Kassam, Anjali K. Henders, Leanne Wallace, Grant Montgomery, Yu-Hsuan Chuang, Steve Horvath, Beate Ritz, Glenda Halliday, Ian Hickie, John B. Kwok, John Pearson, Toni Pitcher, Martin Kennedy, Steven R. Bentley, Peter A. Silburn, Jian Yang, Naomi R. Wray, Simon J. G. Lewis, Tim Anderson, John Dalrymple-Alford, George D. Mellick, Peter M. Visscher, Jacob Gratten
Published 2020-03-01

Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities

by Mintu Chandra, Yanni K.-Y. Chin, Caroline Mas, J. Ryan Feathers, Blessy Paul, Sanchari Datta, Kai-En Chen, Xinying Jia, Zhe Yang, Suzanne J. Norwood, Biswaranjan Mohanty, Andrea Bugarcic, Rohan D. Teasdale, W. Mike Henne, Mehdi Mobli, Brett M. Collins
Published 2019-04-01

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice

by Jeroen Overman, Frank Fontaine, Mehdi Moustaqil, Deepak Mittal, Emma Sierecki, Natalia Sacilotto, Johannes Zuegg, Avril AB Robertson, Kelly Holmes, Angela A Salim, Sreeman Mamidyala, Mark S Butler, Ashley S Robinson, Emmanuelle Lesieur, Wayne Johnston, Kirill Alexandrov, Brian L Black, Benjamin M Hogan, Sarah De Val, Robert J Capon, Jason S Carroll, Timothy L Bailey, Peter Koopman, Ralf Jauch, Mark J Smyth, Matthew A Cooper, Yann Gambin, Mathias Francois
Published 2017-01-01

Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells

by Xuan Sun, Benjamin Cao, Marina Naval-Sanchez, Tony Pham, Yu Bo Yang Sun, Brenda Williams, Shen Y. Heazlewood, Nikita Deshpande, Jinhua Li, Felix Kraus, James Rae, Quan Nguyen, Hamed Yari, Jan Schröder, Chad K. Heazlewood, Madeline Fulton, Jessica Hatwell-Humble, Kaustav Das Gupta, Ronan Kapetanovic, Xiaoli Chen, Matthew J. Sweet, Robert G. Parton, Michael T. Ryan, Jose M. Polo, Christian M. Nefzger, Susan K. Nilsson
Published 2021-05-01

Scaffolding and completing genome assemblies in real-time with nanopore sequencing

by Minh Duc Cao, Son Hoang Nguyen, Devika Ganesamoorthy, Alysha G. Elliott, Matthew A. Cooper, Lachlan J. M. Coin
Published 2017-02-01

The antimicrobial potential of cannabidiol

by Mark A. T. Blaskovich, Angela M. Kavanagh, Alysha G. Elliott, Bing Zhang, Soumya Ramu, Maite Amado, Gabrielle J. Lowe, Alexandra O. Hinton, Do Minh Thu Pham, Johannes Zuegg, Neil Beare, Diana Quach, Marc D. Sharp, Joe Pogliano, Ashleigh P. Rogers, Dena Lyras, Lendl Tan, Nicholas P. West, David W. Crawford, Marnie L. Peterson, Matthew Callahan, Michael Thurn
Published 2021-01-01

Caveolin-1 Is Necessary for Hepatic Oxidative Lipid Metabolism: Evidence for Crosstalk between Caveolin-1 and Bile Acid Signaling

by Manuel A. Fernández-Rojo, Milena Gongora, Rebecca L. Fitzsimmons, Nick Martel, Sheree D. Martin, Susan J. Nixon, Andrew J. Brooks, Maria P. Ikonomopoulou, Sally Martin, Harriet P. Lo, Stephen A. Myers, Christina Restall, Charles Ferguson, Paul F. Pilch, Sean L. McGee, Robin L. Anderson, Michael J. Waters, John F. Hancock, Sean M. Grimmond, George E.O. Muscat, Robert G. Parton
Published 2013-07-01

Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations

by Ying Wang, Jing Guo, Guiyan Ni, Jian Yang, Peter M. Visscher, Loic Yengo
Published 2020-07-01

GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression

by Yeda Wu, Graham K. Murray, Enda M. Byrne, Julia Sidorenko, Peter M. Visscher, Naomi R. Wray
Published 2021-02-01

Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases

by M. A. Jackson, E. K. Gilding, T. Shafee, K. S. Harris, Q. Kaas, S. Poon, K. Yap, H. Jia, R. Guarino, L. Y. Chan, T. Durek, M. A. Anderson, D. J. Craik
Published 2018-06-01

Misestimation of heritability and prediction accuracy of male-pattern baldness

by Chloe X. Yap, Julia Sidorenko, Riccardo E. Marioni, Loic Yengo, Naomi R. Wray, Peter M. Visscher
Published 2018-06-01

ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries

by Josephine Bowles, Chun-Wei Feng, Kim Miles, Jessica Ineson, Cassy Spiller, Peter Koopman
Published 2016-02-01

Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response

by Kerrie-Ann McMahon, David A Stroud, Yann Gambin, Vikas Tillu, Michele Bastiani, Emma Sierecki, Mark E Polinkovsky, Thomas E Hall, Guillermo A Gomez, Yeping Wu, Marie-Odile Parat, Nick Martel, Harriet P Lo, Kum Kum Khanna, Kirill Alexandrov, Roger Daly, Alpha Yap, Michael T Ryan, Robert G Parton
Published 2021-06-01

Laser-mediated rupture of chlamydial inclusions triggers pathogen egress and host cell necrosis

by Markus C. Kerr, Guillermo A. Gomez, Charles Ferguson, Maria C. Tanzer, James M. Murphy, Alpha S. Yap, Robert G. Parton, Wilhelmina M. Huston, Rohan D Teasdale
Published 2017-03-01

Phenotypic covariance across the entire spectrum of relatedness for 86 billion pairs of individuals

by Kathryn E. Kemper, Loic Yengo, Zhili Zheng, Abdel Abdellaoui, Matthew C. Keller, Michael E. Goddard, Naomi R. Wray, Jian Yang, Peter M. Visscher
Published 2021-02-01

Methods in Microbial Biodiscovery

by Angela A. Salim, Zeinab G. Khalil, Ahmed H. Elbanna, Taizong Wu, Robert J. Capon
Published 2021-09-01