Correction to: Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits

by Benjamin S. Glicksberg, Letizia Amadori, Nicholas K. Akers, Katyayani Sukhavasi, Oscar Franzén, Li Li, Gillian M. Belbin, Kristin L. Ayers, Khader Shameer, Marcus A. Badgeley, Kipp W. Johnson, Ben Readhead, Bruce J. Darrow, Eimear E. Kenny, Christer Betsholtz, Raili Ermel, Josefin Skogsberg, Arno Ruusalepp, Eric E. Schadt, Joel T. Dudley, Hongxia Ren, Jason C. Kovacic, Chiara Giannarelli, Shuyu D. Li, Johan L. M. Björkegren, Rong Chen
Published 2019-11-01

Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits

by Benjamin S. Glicksberg, Letizia Amadori, Nicholas K. Akers, Katyayani Sukhavasi, Oscar Franzén, Li Li, Gillian M. Belbin, Kristin L. Akers, Khader Shameer, Marcus A. Badgeley, Kipp W. Johnson, Ben Readhead, Bruce J. Darrow, Eimear E. Kenny, Christer Betsholtz, Raili Ermel, Josefin Skogsberg, Arno Ruusalepp, Eric E. Schadt, Joel T. Dudley, Hongxia Ren, Jason C. Kovacic, Chiara Giannarelli, Shuyu D. Li, Johan L. M. Björkegren, Rong Chen
Published 2019-07-01

Systems modeling of white matter microstructural abnormalities in Alzheimer's disease

by Emrin Horgusluoglu-Moloch, Gaoyu Xiao, Minghui Wang, Qian Wang, Xianxiao Zhou, Kwangsik Nho, Andrew J. Saykin, Eric Schadt, Bin Zhang
Published 2020-01-01

Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas

by Huan Wang, Aaron Bender, Peng Wang, Esra Karakose, William B. Inabnet, Steven K. Libutti, Andrew Arnold, Luca Lambertini, Micheal Stang, Herbert Chen, Yumi Kasai, Milind Mahajan, Yayoi Kinoshita, Gustavo Fernandez-Ranvier, Thomas C. Becker, Karen K. Takane, Laura A. Walker, Shira Saul, Rong Chen, Donald K. Scott, Jorge Ferrer, Yevgeniy Antipin, Michael Donovan, Andrew V. Uzilov, Boris Reva, Eric E. Schadt, Bojan Losic, Carmen Argmann, Andrew F. Stewart
Published 2017-10-01

Impacts of incorporating personal genome sequencing into graduate genomics education: a longitudinal study over three course years

by Michael D. Linderman, Saskia C. Sanderson, Ali Bashir, George A. Diaz, Andrew Kasarskis, Randi Zinberg, Milind Mahajan, Sabrina A. Suckiel, Micol Zweig, Eric E. Schadt
Published 2018-01-01

Gut microbiota density influences host physiology and is shaped by host and microbial factors

by Eduardo J Contijoch, Graham J Britton, Chao Yang, Ilaria Mogno, Zhihua Li, Ruby Ng, Sean R Llewellyn, Sheela Hira, Crystal Johnson, Keren M Rabinowitz, Revital Barkan, Iris Dotan, Robert P Hirten, Shih-Chen Fu, Yuying Luo, Nancy Yang, Tramy Luong, Philippe R Labrias, Sergio Lira, Inga Peter, Ari Grinspan, Jose C Clemente, Roman Kosoy, Seunghee Kim-Schulze, Xiaochen Qin, Anabella Castillo, Amanda Hurley, Ashish Atreja, Jason Rogers, Farah Fasihuddin, Merjona Saliaj, Amy Nolan, Pamela Reyes-Mercedes, Carina Rodriguez, Sarah Aly, Kenneth Santa-Cruz, Lauren Peters, Mayte Suárez-Fariñas, Ruiqi Huang, Ke Hao, Jun Zhu, Bin Zhang, Bojan Losic, Haritz Irizar, Won-Min Song, Antonio Di Narzo, Wenhui Wang, Benjamin L Cohen, Christopher DiMaio, David Greenwald, Steven Itzkowitz, Aimee Lucas, James Marion, Elana Maser, Ryan Ungaro, Steven Naymagon, Joshua Novak, Brijen Shah, Thomas Ullman, Peter Rubin, James George, Peter Legnani, Shannon E Telesco, Joshua R Friedman, Carrie Brodmerkel, Scott Plevy, Judy H Cho, Jean-Frederic Colombel, Eric E Schadt, Carmen Argmann, Marla Dubinsky, Andrew Kasarskis, Bruce Sands, Jeremiah J Faith
Published 2019-01-01

A reference profile-free deconvolution method to infer cancer cell-intrinsic subtypes and tumor-type-specific stromal profiles

by Li Wang, Robert P. Sebra, John P. Sfakianos, Kimaada Allette, Wenhui Wang, Seungyeul Yoo, Nina Bhardwaj, Eric E. Schadt, Xin Yao, Matthew D. Galsky, Jun Zhu
Published 2020-02-01

Enabling Precision Cardiology Through Multiscale Biology and Systems Medicine

by Kipp W. Johnson, BS, Khader Shameer, PhD, Benjamin S. Glicksberg, BS, Ben Readhead, MBBS, Partho P. Sengupta, MD, Johan L.M. Björkegren, MD, PhD, Jason C. Kovacic, MD, PhD, Joel T. Dudley, PhD
Published 2017-06-01

A Drosophila platform identifies a novel, personalized therapy for a patient with adenoid cystic carcinoma

by Erdem Bangi, Peter Smibert, Andrew V. Uzilov, Alexander G. Teague, Sindhura Gopinath, Yevgeniy Antipin, Rong Chen, Chana Hecht, Nelson Gruszczynski, Wesley J. Yon, Denis Malyshev, Denise Laspina, Isaiah Selkridge, Huan Wang, Jorge Gomez, John Mascarenhas, Aye S. Moe, Chun Yee Lau, Patricia Taik, Chetanya Pandya, Max Sung, Sara Kim, Kendra Yum, Robert Sebra, Michael Donovan, Krzysztof Misiukiewicz, Celina Ang, Eric E. Schadt, Marshall R. Posner, Ross L. Cagan
Published 2021-03-01

A Systems Approach Identifies Networks and Genes Linking Sleep and Stress: Implications for Neuropsychiatric Disorders

by Peng Jiang, Joseph R. Scarpa, Karrie Fitzpatrick, Bojan Losic, Vance D. Gao, Ke Hao, Keith C. Summa, He S. Yang, Bin Zhang, Ravi Allada, Martha H. Vitaterna, Fred W. Turek, Andrew Kasarskis
Published 2015-05-01

Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci

by Clint L. Miller, Milos Pjanic, Ting Wang, Trieu Nguyen, Ariella Cohain, Jonathan D. Lee, Ljubica Perisic, Ulf Hedin, Ramendra K. Kundu, Deshna Majmudar, Juyong B. Kim, Oliver Wang, Christer Betsholtz, Arno Ruusalepp, Oscar Franzén, Themistocles L. Assimes, Stephen B. Montgomery, Eric E. Schadt, Johan L.M. Björkegren, Thomas Quertermous
Published 2016-07-01

Molecular classification and prediction in gastric cancer

by Xiandong Lin, Yongzhong Zhao, Won-min Song, Bin Zhang
Published 2015-01-01

Cancer gene profiling in non-small cell lung cancers reveals activating mutations in JAK2 and JAK3 with therapeutic implications

by Shuyu D. Li, Meng Ma, Hui Li, Aneta Waluszko, Tatyana Sidorenko, Eric E. Schadt, David Y. Zhang, Rong Chen, Fei Ye
Published 2017-10-01

Zooming in on Inflammatory Bowel Disease: Microbial and Proteomic Features Associated With IBD in Colonic Microenvironments

by Sabrina Tamburini, PhD, Jose C. Clemente, PhD
Published 2016-09-01

Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells

by Aaron Topol, Shijia Zhu, Brigham J. Hartley, Jane English, Mads E. Hauberg, Ngoc Tran, Chelsea Ann Rittenhouse, Anthony Simone, Douglas M. Ruderfer, Jessica Johnson, Ben Readhead, Yoav Hadas, Peter A. Gochman, Ying-Chih Wang, Hardik Shah, Gerard Cagney, Judith Rapoport, Fred H. Gage, Joel T. Dudley, Pamela Sklar, Manuel Mattheisen, David Cotter, Gang Fang, Kristen J. Brennand
Published 2016-05-01

A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection

by Slim Fourati, Aarthi Talla, Mehrad Mahmoudian, Joshua G. Burkhart, Riku Klén, Ricardo Henao, Thomas Yu, Zafer Aydın, Ka Yee Yeung, Mehmet Eren Ahsen, Reem Almugbel, Samad Jahandideh, Xiao Liang, Torbjörn E. M. Nordling, Motoki Shiga, Ana Stanescu, Robert Vogel, The Respiratory Viral DREAM Challenge Consortium, Gaurav Pandey, Christopher Chiu, Micah T. McClain, Christopher W. Woods, Geoffrey S. Ginsburg, Laura L. Elo, Ephraim L. Tsalik, Lara M. Mangravite, Solveig K. Sieberts
Published 2018-10-01

Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior

by Mar Gacias, Sevasti Gaspari, Patricia-Mae G Santos, Sabrina Tamburini, Monica Andrade, Fan Zhang, Nan Shen, Vladimir Tolstikov, Michael A Kiebish, Jeffrey L Dupree, Venetia Zachariou, Jose C Clemente, Patrizia Casaccia
Published 2016-04-01

A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis

by Seungyeul Yoo, Wenhui Wang, Qin Wang, M Isabel Fiel, Eunjee Lee, Spiros P. Hiotis, Jun Zhu
Published 2017-12-01

Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth

by Xiumei Hong, Ke Hao, Hongkai Ji, Shouneng Peng, Ben Sherwood, Antonio Di Narzo, Hui-Ju Tsai, Xin Liu, Irina Burd, Guoying Wang, Yuelong Ji, Deanna Caruso, Guangyun Mao, Tami R. Bartell, Zhongyang Zhang, Colleen Pearson, Linda Heffner, Sandra Cerda, Terri H. Beaty, M. Daniele Fallin, Aviva Lee-Parritz, Barry Zuckerman, Daniel E. Weeks, Xiaobin Wang
Published 2017-06-01

The genome of a subterrestrial nematode reveals adaptations to heat

by Deborah J. Weinstein, Sarah E. Allen, Maggie C. Y. Lau, Mariana Erasmus, Kathryn C. Asalone, Kathryn Walters-Conte, Gintaras Deikus, Robert Sebra, Gaetan Borgonie, Esta van Heerden, Tullis C. Onstott, John R. Bracht
Published 2019-11-01