PAPERCLIP Identifies MicroRNA Targets and a Role of CstF64/64tau in Promoting Non-canonical poly(A) Site Usage

by Hun-Way Hwang, Christopher Y. Park, Hani Goodarzi, John J. Fak, Aldo Mele, Michael J. Moore, Yuhki Saito, Robert B. Darnell
Published 2016-04-01

Single-Cell, Genome-wide Sequencing Identifies Clonal Somatic Copy-Number Variation in the Human Brain

by Xuyu Cai, Gilad D. Evrony, Hillel S. Lehmann, Princess C. Elhosary, Bhaven K. Mehta, Annapurna Poduri, Christopher A. Walsh
Published 2014-09-01

Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration

by Guiping Wang, David J Simon, Zhuhao Wu, Deanna M Belsky, Evan Heller, Melanie K O'Rourke, Nicholas T Hertz, Henrik Molina, Guisheng Zhong, Marc Tessier-Lavigne, Xiaowei Zhuang
Published 2019-05-01

Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation

by Zhengjian Zhang, Zarko Boskovic, Mahmud M Hussain, Wenxin Hu, Carla Inouye, Han-Je Kim, A Katherine Abole, Mary K Doud, Timothy A Lewis, Angela N Koehler, Stuart L Schreiber, Robert Tjian
Published 2015-08-01

Single-cell transcriptomes of developing and adult olfactory receptor neurons in Drosophila

by Colleen N McLaughlin, Maria Brbić, Qijing Xie, Tongchao Li, Felix Horns, Sai Saroja Kolluru, Justus M Kebschull, David Vacek, Anthony Xie, Jiefu Li, Robert C Jones, Jure Leskovec, Stephen R Quake, Liqun Luo, Hongjie Li
Published 2021-02-01

A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome

by Jefferson J Doyle, Alexander J Doyle, Nicole K Wilson, Jennifer P Habashi, Djahida Bedja, Ryan E Whitworth, Mark E Lindsay, Florian Schoenhoff, Loretha Myers, Nick Huso, Suha Bachir, Oliver Squires, Benjamin Rusholme, Hamid Ehsan, David Huso, Craig J Thomas, Mark J Caulfield, Jennifer E Van Eyk, Daniel P Judge, Harry C Dietz, GenTAC Registry Consortium, MIBAVA Leducq Consortium
Published 2015-10-01

Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation

by Zhong Zheng, Linda Zhang, Xiao-Long Cui, Xianbin Yu, Phillip J. Hsu, Ruitu Lyu, Haiyan Tan, Malay Mandal, Michelle Zhang, Hui-Lung Sun, Arantxa Sanchez Castillo, Junmin Peng, Marcus R. Clark, Chuan He, Haochu Huang
Published 2020-06-01

Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity

by Pascal Krotee, Jose A Rodriguez, Michael R Sawaya, Duilio Cascio, Francis E Reyes, Dan Shi, Johan Hattne, Brent L Nannenga, Marie E Oskarsson, Stephan Philipp, Sarah Griner, Lin Jiang, Charles G Glabe, Gunilla T Westermark, Tamir Gonen, David S Eisenberg
Published 2017-01-01

Molecular mechanism of activation-triggered subunit exchange in Ca2+/calmodulin-dependent protein kinase II

by Moitrayee Bhattacharyya, Margaret M Stratton, Catherine C Going, Ethan D McSpadden, Yongjian Huang, Anna C Susa, Anna Elleman, Yumeng Melody Cao, Nishant Pappireddi, Pawel Burkhardt, Christine L Gee, Tiago Barros, Howard Schulman, Evan R Williams, John Kuriyan
Published 2016-03-01

An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms

by Oguz Kanca, Jonathan Zirin, Jorge Garcia-Marques, Shannon Marie Knight, Donghui Yang-Zhou, Gabriel Amador, Hyunglok Chung, Zhongyuan Zuo, Liwen Ma, Yuchun He, Wen-Wen Lin, Ying Fang, Ming Ge, Shinya Yamamoto, Karen L Schulze, Yanhui Hu, Allan C Spradling, Stephanie E Mohr, Norbert Perrimon, Hugo J Bellen
Published 2019-11-01

Astrocytes integrate and drive action potential firing in inhibitory subnetworks

by Tara Deemyad, Joel Lüthi, Nelson Spruston
Published 2018-10-01

Low-noise encoding of active touch by layer 4 in the somatosensory cortex

by Samuel Andrew Hires, Diego A Gutnisky, Jianing Yu, Daniel H O'Connor, Karel Svoboda
Published 2015-08-01

Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel

by Binsen Li, Peng Ge, Kevin A. Murray, Phorum Sheth, Meng Zhang, Gayatri Nair, Michael R. Sawaya, Woo Shik Shin, David R. Boyer, Shulin Ye, David S. Eisenberg, Z. Hong Zhou, Lin Jiang
Published 2018-09-01

Direct mechanical stimulation of tip links in hair cells through DNA tethers

by Aakash Basu, Samuel Lagier, Maria Vologodskaia, Brian A Fabella, AJ Hudspeth
Published 2016-06-01

<i>Ephus</i>: multipurpose data acquisition software for neuroscience experiments

by Benjamin A Suter, Timothy O'Connor, Vijay Iyer, Leopoldo Petreanu, Bryan M Hooks, Taro Kiritani, Karel Svoboda, Gordon M. G Shepherd, Gordon M. G Shepherd
Published 2010-08-01

Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling

by Eunhee Choi, Sotaro Kikuchi, Haishan Gao, Karolina Brodzik, Ibrahim Nassour, Adam Yopp, Amit G. Singal, Hao Zhu, Hongtao Yu
Published 2019-04-01

Auxin-sensitive Aux/IAA proteins mediate drought tolerance in Arabidopsis by regulating glucosinolate levels

by Mohammad Salehin, Baohua Li, Michelle Tang, Ella Katz, Liang Song, Joseph R. Ecker, Daniel J. Kliebenstein, Mark Estelle
Published 2019-09-01

HSP90 regulates temperature-dependent seedling growth in Arabidopsis by stabilizing the auxin co-receptor F-box protein TIR1

by Renhou Wang, Yi Zhang, Martin Kieffer, Hong Yu, Stefan Kepinski, Mark Estelle
Published 2016-01-01

The genetic basis and fitness consequences of sperm midpiece size in deer mice

by Heidi S. Fisher, Emily Jacobs-Palmer, Jean-Marc Lassance, Hopi E. Hoekstra
Published 2016-12-01

Visible light reduces C. elegans longevity

by C. Daniel De Magalhaes Filho, Brian Henriquez, Nicole E. Seah, Ronald M. Evans, Louis R. Lapierre, Andrew Dillin
Published 2018-03-01