The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation

by Yongjie Wei, Zhenyi An, Zhongju Zou, Rhea Sumpter Jr, Minfei Su, Xiao Zang, Sangita Sinha, Matthias Gaestel, Beth Levine
Published 2015-02-01

The human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochores

by Sushama Sivakumar, Paweł Ł Janczyk, Qianhui Qu, Chad A Brautigam, P Todd Stukenberg, Hongtao Yu, Gary J Gorbsky
Published 2016-03-01

A general strategy to construct small molecule biosensors in eukaryotes

by Justin Feng, Benjamin W Jester, Christine E Tinberg, Daniel J Mandell, Mauricio S Antunes, Raj Chari, Kevin J Morey, Xavier Rios, June I Medford, George M Church, Stanley Fields, David Baker
Published 2015-12-01

The budding yeast Centromere DNA Element II wraps a stable Cse4 hemisome in either orientation in vivo

by Steven Henikoff, Srinivas Ramachandran, Kristina Krassovsky, Terri D Bryson, Christine A Codomo, Kristin Brogaard, Jonathan Widom, Ji-Ping Wang, Jorja G Henikoff
Published 2014-04-01

Bile salt receptor complex activates a pathogenic type III secretion system

by Peng Li, Giomar Rivera-Cancel, Lisa N Kinch, Dor Salomon, Diana R Tomchick, Nick V Grishin, Kim Orth
Published 2016-07-01

Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion

by Xin Rong, Bo Wang, Merlow M Dunham, Per Niklas Hedde, Jinny S Wong, Enrico Gratton, Stephen G Young, David A Ford, Peter Tontonoz
Published 2015-03-01

Evolutionary consequences of intra-patient phage predation on microbial populations

by Kimberley D Seed, Minmin Yen, B Jesse Shapiro, Isabelle J Hilaire, Richelle C Charles, Jessica E Teng, Louise C Ivers, Jacques Boncy, Jason B Harris, Andrew Camilli
Published 2014-08-01

Flagellar membrane fusion and protein exchange in trypanosomes; a new form of cell-cell communication? [version 1; referees: 2 approved]

by Simon Imhof, Cristina Fragoso, Andrew Hemphill, Conrad von Schubert, Dong Li, Wesley Legant, Eric Betzig, Isabel Roditi
Published 2016-04-01

The Coding Regions of Germline mRNAs Confer Sensitivity to Argonaute Regulation in C. elegans

by Meetu Seth, Masaki Shirayama, Wen Tang, En-Zhi Shen, Shikui Tu, Heng-Chi Lee, Zhiping Weng, Craig C. Mello
Published 2018-02-01

Immune Escape via a Transient Gene Expression Program Enables Productive Replication of a Latent Pathogen

by Jessica A. Linderman, Mariko Kobayashi, Vinayak Rayannavar, John J. Fak, Robert B. Darnell, Moses V. Chao, Angus C. Wilson, Ian Mohr
Published 2017-01-01

Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor

by Simon Jenni, Louis-Marie Bloyet, Ruben Diaz-Avalos, Bo Liang, Sean P.J. Whelan, Nikolaus Grigorieff, Stephen C. Harrison
Published 2020-01-01

High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice

by Tata Nageswara Rao, Jonathan Marks-Bluth, Jessica Sullivan, Manoj K. Gupta, Vashe Chandrakanthan, Simon R. Fitch, Katrin Ottersbach, Young C. Jang, Xianhua Piao, Rohit N. Kulkarni, Thomas Serwold, John E. Pimanda, Amy J. Wagers
Published 2015-05-01

Caspase-11 Controls Interleukin-1β Release through Degradation of TRPC1

by Bénédicte F. Py, Mingzhi Jin, Bimal N. Desai, Anirudh Penumaka, Hong Zhu, Maike Kober, Alexander Dietrich, Marta M. Lipinski, Thomas Henry, David E. Clapham, Junying Yuan
Published 2014-03-01

Synaptotagmin 7 is targeted to the axonal plasma membrane through γ-secretase processing to promote synaptic vesicle docking in mouse hippocampal neurons

by Jason D Vevea, Grant F Kusick, Kevin C Courtney, Erin Chen, Shigeki Watanabe, Edwin R Chapman
Published 2021-09-01

Locating macromolecular assemblies in cells by 2D template matching with cisTEM

by Bronwyn A Lucas, Benjamin A Himes, Liang Xue, Timothy Grant, Julia Mahamid, Nikolaus Grigorieff
Published 2021-06-01

Syncrip/hnRNP Q influences synaptic transmission and regulates BMP signaling at the Drosophila neuromuscular synapse

by James M. Halstead, Yong Qi Lin, Lita Durraine, Russell S. Hamilton, Graeme Ball, Greg G. Neely, Hugo J. Bellen, Ilan Davis
Published 2014-08-01

The small molecule phenamil is a modulator of adipocyte differentiation and PPARγ expression[S]

by Kye Won Park, Hironori Waki, Sung-Pil Choi, Ki-Moon Park, Peter Tontonoz
Published 2010-09-01

Structure of the substrate-engaged SecA-SecY protein translocation machine

by Chengying Ma, Xiaofei Wu, Dongjie Sun, Eunyong Park, Marco A. Catipovic, Tom A. Rapoport, Ning Gao, Long Li
Published 2019-06-01

Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction

by Kyle R. Simonetta, Joshua Taygerly, Kathleen Boyle, Stephen E. Basham, Chris Padovani, Yan Lou, Thomas J. Cummins, Stephanie L. Yung, Szerenke Kiss von Soly, Frank Kayser, John Kuriyan, Michael Rape, Mario Cardozo, Mark A. Gallop, Neil F. Bence, Paul A. Barsanti, Anjanabha Saha
Published 2019-03-01

Chronology-based architecture of descending circuits that underlie the development of locomotor repertoire after birth

by Avinash Pujala, Minoru Koyama
Published 2019-02-01