Defining a Spinal Microcircuit that Gates Myelinated Afferent Input: Implications for Tactile Allodynia

by Kieran A. Boyle, Mark A. Gradwell, Toshiharu Yasaka, Allen C. Dickie, Erika Polgár, Robert P. Ganley, Desmond P.H. Orr, Masahiko Watanabe, Victoria E. Abraira, Emily D. Kuehn, Amanda L. Zimmerman, David D. Ginty, Robert J. Callister, Brett A. Graham, David I. Hughes
Published 2019-07-01

Molecular basis for multimerization in the activation of the epidermal growth factor receptor

by Yongjian Huang, Shashank Bharill, Deepti Karandur, Sean M Peterson, Morgan Marita, Xiaojun Shi, Megan J Kaliszewski, Adam W Smith, Ehud Y Isacoff, John Kuriyan
Published 2016-03-01

Analysis of the mechanosensor channel functionality of TACAN

by Yiming Niu, Xiao Tao, George Vaisey, Paul Dominic B Olinares, Hanan Alwaseem, Brian T Chait, Roderick MacKinnon
Published 2021-08-01

DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7

by Lorraine De Jesús-Kim, Larry J Friedman, Marko Lõoke, Christian K Ramsoomair, Jeff Gelles, Stephen P Bell
Published 2021-02-01

The dynamic nature of the human origin recognition complex revealed through five cryoEM structures

by Matt J Jaremko, Kin Fan On, Dennis R Thomas, Bruce Stillman, Leemor Joshua-Tor
Published 2020-08-01

Cryo-EM structure of the mechanically activated ion channel OSCA1.2

by Sebastian Jojoa-Cruz, Kei Saotome, Swetha E Murthy, Che Chun Alex Tsui, Mark SP Sansom, Ardem Patapoutian, Andrew B Ward
Published 2018-11-01

Variability of cholesterol accessibility in human red blood cells measured using a bacterial cholesterol-binding toxin

by Rima S Chakrabarti, Sally A Ingham, Julia Kozlitina, Austin Gay, Jonathan C Cohen, Arun Radhakrishnan, Helen H Hobbs
Published 2017-02-01

Mechanism of ribosome rescue by ArfA and RF2

by Gabriel Demo, Egor Svidritskiy, Rohini Madireddy, Ruben Diaz-Avalos, Timothy Grant, Nikolaus Grigorieff, Duncan Sousa, Andrei A Korostelev
Published 2017-03-01

BHLHE40, a third transcription factor required for insulin induction of SREBP-1c mRNA in rodent liver

by Jing Tian, Jiaxi Wu, Xiang Chen, Tong Guo, Zhijian J Chen, Joseph L Goldstein, Michael S Brown
Published 2018-06-01

Cytokine receptor-Eb1 interaction couples cell polarity and fate during asymmetric cell division

by Cuie Chen, Ryan Cummings, Aghapi Mordovanakis, Alan J Hunt, Michael Mayer, David Sept, Yukiko M Yamashita
Published 2018-03-01

CD301b+ dendritic cells suppress T follicular helper cells and antibody responses to protein antigens

by Yosuke Kumamoto, Toshiro Hirai, Patrick W Wong, Daniel H Kaplan, Akiko Iwasaki
Published 2016-09-01

Small molecule inhibition of Csk alters affinity recognition by T cells

by Boryana N Manz, Ying Xim Tan, Adam H Courtney, Florentine Rutaganira, Ed Palmer, Kevan M Shokat, Arthur Weiss
Published 2015-08-01

Mapping translation 'hot-spots' in live cells by tracking single molecules of mRNA and ribosomes

by Zachary B Katz, Brian P English, Timothée Lionnet, Young J Yoon, Nilah Monnier, Ben Ovryn, Mark Bathe, Robert H Singer
Published 2016-01-01

MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades

by Siqi Liu, Jueqi Chen, Xin Cai, Jiaxi Wu, Xiang Chen, You-Tong Wu, Lijun Sun, Zhijian J Chen
Published 2013-08-01

Evidence for a DNA-relay mechanism in ParABS-mediated chromosome segregation

by Hoong Chuin Lim, Ivan Vladimirovich Surovtsev, Bruno Gabriel Beltran, Fang Huang, Jörg Bewersdorf, Christine Jacobs-Wagner
Published 2014-05-01

Tracking transcription factor mobility and interaction in Arabidopsis roots with fluorescence correlation spectroscopy

by Natalie M Clark, Elizabeth Hinde, Cara M Winter, Adam P Fisher, Giuseppe Crosti, Ikram Blilou, Enrico Gratton, Philip N Benfey, Rosangela Sozzani
Published 2016-06-01

Core promoter factor TAF9B regulates neuronal gene expression

by Francisco J Herrera, Teppei Yamaguchi, Henk Roelink, Robert Tjian
Published 2014-07-01

Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster

by Joshua G Dunn, Catherine K Foo, Nicolette G Belletier, Elizabeth R Gavis, Jonathan S Weissman
Published 2013-12-01

Three-color single molecule imaging shows WASP detachment from Arp2/3 complex triggers actin filament branch formation

by Benjamin A Smith, Shae B Padrick, Lynda K Doolittle, Karen Daugherty-Clarke, Ivan R Corrêa Jr, Ming-Qun Xu, Bruce L Goode, Michael K Rosen, Jeff Gelles
Published 2013-09-01

A role for PVRL4-driven cell–cell interactions in tumorigenesis

by Natalya N Pavlova, Christian Pallasch, Andrew EH Elia, Christian J Braun, Thomas F Westbrook, Michael Hemann, Stephen J Elledge
Published 2013-04-01