Excitatory transmission onto AgRP neurons is regulated by cJun NH2-terminal kinase 3 in response to metabolic stress

by Santiago Vernia, Caroline Morel, Joseph C Madara, Julie Cavanagh-Kyros, Tamera Barrett, Kathryn Chase, Norman J Kennedy, Dae Young Jung, Jason K Kim, Neil Aronin, Richard A Flavell, Bradford B Lowell, Roger J Davis
Published 2016-02-01

A PEROXO-Tag Enables Rapid Isolation of Peroxisomes from Human Cells

by G. Jordan Ray, Elizabeth A. Boydston, Emily Shortt, Gregory A. Wyant, Sebastian Lourido, Walter W. Chen, David M. Sabatini
Published 2020-05-01

Mapping Brain-Wide Afferent Inputs of Parvalbumin-Expressing GABAergic Neurons in Barrel Cortex Reveals Local and Long-Range Circuit Motifs

by Georg Hafner, Mirko Witte, Julien Guy, Nidhi Subhashini, Lief E. Fenno, Charu Ramakrishnan, Yoon Seok Kim, Karl Deisseroth, Edward M. Callaway, Martina Oberhuber, Karl-Klaus Conzelmann, Jochen F. Staiger
Published 2019-09-01

lncRNA requirements for mouse acute myeloid leukemia and normal differentiation

by M Joaquina Delás, Leah R Sabin, Egor Dolzhenko, Simon RV Knott, Ester Munera Maravilla, Benjamin T Jackson, Sophia A Wild, Tatjana Kovacevic, Eva Maria Stork, Meng Zhou, Nicolas Erard, Emily Lee, David R Kelley, Mareike Roth, Inês AM Barbosa, Johannes Zuber, John L Rinn, Andrew D Smith, Gregory J Hannon
Published 2017-09-01

A scalable solution for isolating human multipotent clinical-grade neural stem cells from ES precursors

by Dasa Bohaciakova, Marian Hruska-Plochan, Rachel Tsunemoto, Wesley D. Gifford, Shawn P. Driscoll, Thomas D. Glenn, Stephanie Wu, Silvia Marsala, Michael Navarro, Takahiro Tadokoro, Stefan Juhas, Jana Juhasova, Oleksandr Platoshyn, David Piper, Vickie Sheckler, Dara Ditsworth, Samuel L. Pfaff, Martin Marsala
Published 2019-03-01

Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies

by Margarita Parada-Kusz, Cristina Penaranda, Elliott J. Hagedorn, Anne Clatworthy, Anil V. Nair, Jonathan E. Henninger, Christoph Ernst, Brian Li, Raquel Riquelme, Humberto Jijon, Eduardo J. Villablanca, Leonard I. Zon, Deborah Hung, Miguel L. Allende
Published 2018-11-01

Two locus inheritance of non-syndromic midline craniosynostosis via rare SMAD6 and common BMP2 alleles

by Andrew T Timberlake, Jungmin Choi, Samir Zaidi, Qiongshi Lu, Carol Nelson-Williams, Eric D Brooks, Kaya Bilguvar, Irina Tikhonova, Shrikant Mane, Jenny F Yang, Rajendra Sawh-Martinez, Sarah Persing, Elizabeth G Zellner, Erin Loring, Carolyn Chuang, Amy Galm, Peter W Hashim, Derek M Steinbacher, Michael L DiLuna, Charles C Duncan, Kevin A Pelphrey, Hongyu Zhao, John A Persing, Richard P Lifton
Published 2016-09-01

Brain-specific inhibition of mTORC1 eliminates side effects resulting from mTORC1 blockade in the periphery and reduces alcohol intake in mice

by Yann Ehinger, Ziyang Zhang, Khanhky Phamluong, Drishti Soneja, Kevan M. Shokat, Dorit Ron
Published 2021-07-01

Detailed modeling of positive selection improves detection of cancer driver genes

by Siming Zhao, Jun Liu, Pranav Nanga, Yuwen Liu, A. Ercument Cicek, Nicholas Knoblauch, Chuan He, Matthew Stephens, Xin He
Published 2019-07-01

Author Correction: Sas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosome

by Jayachandran Gopalakrishnan, Vito Mennella, Stephanie Blachon, Bo Zhai, Andrew H. Smith, Timothy L. Megraw, Daniela Nicastro, Steven P. Gygi, David A. Agard, Tomer Avidor-Reiss
Published 2020-04-01

Improved split fluorescent proteins for endogenous protein labeling

by Siyu Feng, Sayaka Sekine, Veronica Pessino, Han Li, Manuel D. Leonetti, Bo Huang
Published 2017-08-01

Chromatin topology is coupled to Polycomb group protein subnuclear organization

by Ajazul H. Wani, Alistair N. Boettiger, Patrick Schorderet, Ayla Ergun, Christine Münger, Ruslan I. Sadreyev, Xiaowei Zhuang, Robert E. Kingston, Nicole J. Francis
Published 2016-01-01

The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation

by Mehrpouya B. Mobin, Stefanie Gerstberger, Daniel Teupser, Benedetta Campana, Klaus Charisse, Markus H. Heim, Muthiah Manoharan, Thomas Tuschl, Markus Stoffel
Published 2016-09-01

The coordination of nuclear envelope assembly and chromosome segregation in metazoans

by Shiwei Liu, David Pellman
Published 2020-01-01

Phosphoinositide phosphatases and disease

by Philip W. Majerus, John D. York
Published 2009-01-01

CryoEM structure of the antibacterial target PBP1b at 3.3 Å resolution

by Nathanael A. Caveney, Sean D. Workman, Rui Yan, Claire E. Atkinson, Zhiheng Yu, Natalie C. J. Strynadka
Published 2021-05-01

Information flow, cell types and stereotypy in a full olfactory connectome

by Philipp Schlegel, Alexander Shakeel Bates, Tomke Stürner, Sridhar R Jagannathan, Nikolas Drummond, Joseph Hsu, Laia Serratosa Capdevila, Alexandre Javier, Elizabeth C Marin, Asa Barth-Maron, Imaan FM Tamimi, Feng Li, Gerald M Rubin, Stephen M Plaza, Marta Costa, Gregory S X E Jefferis
Published 2021-05-01

Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction

by Anand Ranjan, Vu Q Nguyen, Sheng Liu, Jan Wisniewski, Jee Min Kim, Xiaona Tang, Gaku Mizuguchi, Ejlal Elalaoui, Timothy J Nickels, Vivian Jou, Brian P English, Qinsi Zheng, Ed Luk, Luke D Lavis, Timothee Lionnet, Carl Wu
Published 2020-04-01

Herpes simplex type 2 virus deleted in glycoprotein D protects against vaginal, skin and neural disease

by Christopher Petro, Pablo A González, Natalia Cheshenko, Thomas Jandl, Nazanin Khajoueinejad, Angèle Bénard, Mayami Sengupta, Betsy C Herold, William R Jacobs Jr
Published 2015-03-01

Cytoskeletal Control of Antigen-Dependent T Cell Activation

by Huw Colin-York, Yousef Javanmardi, Mark Skamrahl, Sudha Kumari, Veronica T. Chang, Satya Khuon, Aaron Taylor, Teng-Leong Chew, Eric Betzig, Emad Moeendarbary, Vincenzo Cerundolo, Christian Eggeling, Marco Fritzsche
Published 2019-03-01