Robust model-based analysis of single-particle tracking experiments with Spot-On

by Anders S Hansen, Maxime Woringer, Jonathan B Grimm, Luke D Lavis, Robert Tjian, Xavier Darzacq
Published 2018-01-01

Multi-view light-sheet imaging and tracking with the MaMuT software reveals the cell lineage of a direct developing arthropod limb

by Carsten Wolff, Jean-Yves Tinevez, Tobias Pietzsch, Evangelia Stamataki, Benjamin Harich, Léo Guignard, Stephan Preibisch, Spencer Shorte, Philipp J Keller, Pavel Tomancak, Anastasios Pavlopoulos
Published 2018-03-01

Fine-tuning of substrate preferences of the Src-family kinase Lck revealed through a high-throughput specificity screen

by Neel H Shah, Mark Löbel, Arthur Weiss, John Kuriyan
Published 2018-03-01

Loss of the liver X receptor LXRα/β in peripheral sensory neurons modifies energy expenditure

by Virginie Mansuy-Aubert, Laurent Gautron, Syann Lee, Angie L Bookout, Christine M Kusminski, Kai Sun, Yuan Zhang, Philipp E Scherer, David J Mangelsdorf, Joel K Elmquist
Published 2015-06-01

Dynamics and heterogeneity of a fate determinant during transition towards cell differentiation

by Nicolás Peláez, Arnau Gavalda-Miralles, Bao Wang, Heliodoro Tejedor Navarro, Herman Gudjonson, Ilaria Rebay, Aaron R Dinner, Aggelos K Katsaggelos, Luís AN Amaral, Richard W Carthew
Published 2015-11-01

Dynamic regulation of transcription factors by nucleosome remodeling

by Ming Li, Arjan Hada, Payel Sen, Lola Olufemi, Michael A Hall, Benjamin Y Smith, Scott Forth, Jeffrey N McKnight, Ashok Patel, Gregory D Bowman, Blaine Bartholomew, Michelle D Wang
Published 2015-06-01

LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling

by Ayaka Ito, Cynthia Hong, Xin Rong, Xuewei Zhu, Elizabeth J Tarling, Per Niklas Hedde, Enrico Gratton, John Parks, Peter Tontonoz
Published 2015-07-01

A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity

by Jason Tien, Christian J Peters, Xiu Ming Wong, Tong Cheng, Yuh Nung Jan, Lily Yeh Jan, Huanghe Yang
Published 2014-06-01

mRNA poly(A)-tail changes specified by deadenylation broadly reshape translation in Drosophila oocytes and early embryos

by Stephen W Eichhorn, Alexander O Subtelny, Iva Kronja, Jamie C Kwasnieski, Terry L Orr-Weaver, David P Bartel
Published 2016-07-01

A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility in Drosophila melanogaster

by Maulik R Patel, Ganesh K Miriyala, Aimee J Littleton, Heiko Yang, Kien Trinh, Janet M Young, Scott R Kennedy, Yukiko M Yamashita, Leo J Pallanck, Harmit S Malik
Published 2016-08-01

Balance Control Mediated by Vestibular Circuits Directing Limb Extension or Antagonist Muscle Co-activation

by Andrew J. Murray, Katherine Croce, Timothy Belton, Turgay Akay, Thomas M. Jessell
Published 2018-01-01

Characterization of the ABC methionine transporter from Neisseria meningitidis reveals that lipidated MetQ is required for interaction

by Naima G Sharaf, Mona Shahgholi, Esther Kim, Jeffrey Y Lai, David G VanderVelde, Allen T Lee, Douglas C Rees
Published 2021-08-01

Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells

by Rebecca A. Faulkner, Andrew D. Nguyen, Youngah Jo, Russell A. DeBose-Boyd
Published 2013-04-01

Tight nanoscale clustering of Fcγ receptors using DNA origami promotes phagocytosis

by Nadja Kern, Rui Dong, Shawn M Douglas, Ronald D Vale, Meghan A Morrissey
Published 2021-06-01

Both K63 and K48 ubiquitin linkages signal lysosomal degradation of the LDL receptor

by Li Zhang, Ming Xu, Elena Scotti, Zhijian J. Chen, Peter Tontonoz
Published 2013-05-01

Speed dependent descending control of freezing behavior in Drosophila melanogaster

by Ricardo Zacarias, Shigehiro Namiki, Gwyneth M. Card, Maria Luisa Vasconcelos, Marta A. Moita
Published 2018-09-01

Intrinsic resistance of HIV-infected macrophages to CTL-mediated killing drives immune activation

by K. Clayton, D. Collins, J. Lengieza, J. Lieberman, B. Walker
Published 2017-12-01

Functional genome-wide siRNA screen identifies KIAA0586 as mutated in Joubert syndrome

by Susanne Roosing, Matan Hofree, Sehyun Kim, Eric Scott, Brett Copeland, Marta Romani, Jennifer L Silhavy, Rasim O Rosti, Jana Schroth, Tommaso Mazza, Elide Miccinilli, Maha S Zaki, Kathryn J Swoboda, Joanne Milisa-Drautz, William B Dobyns, Mohamed A Mikati, Faruk İncecik, Matloob Azam, Renato Borgatti, Romina Romaniello, Rose-Mary Boustany, Carol L Clericuzio, Stefano D'Arrigo, Petter Strømme, Eugen Boltshauser, Franco Stanzial, Marisol Mirabelli-Badenier, Isabella Moroni, Enrico Bertini, Francesco Emma, Maja Steinlin, Friedhelm Hildebrandt, Colin A Johnson, Michael Freilinger, Keith K Vaux, Stacey B Gabriel, Pedro Aza-Blanc, Susanne Heynen-Genel, Trey Ideker, Brian D Dynlacht, Ji Eun Lee, Enza Maria Valente, Joon Kim, Joseph G Gleeson
Published 2015-05-01

Gallbladder histopathology during murine gallstone formation: relation to motility and concentrating function

by Karel J. van Erpecum, David Q-H. Wang, Antonio Moschetta, Domenico Ferri, Maria Svelto, Piero Portincasa, Jan-Jaap Hendrickx, Marguérite Schipper, Giuseppe Calamita
Published 2006-01-01

Flexible linkers in CaMKII control the balance between activating and inhibitory autophosphorylation

by Moitrayee Bhattacharyya, Young Kwang Lee, Serena Muratcioglu, Baiyu Qiu, Priya Nyayapati, Howard Schulman, Jay T Groves, John Kuriyan
Published 2020-03-01