Lack of airway submucosal glands impairs respiratory host defenses

by Lynda S Ostedgaard, Margaret P Price, Kristin M Whitworth, Mahmoud H Abou Alaiwa, Anthony J Fischer, Akshaya Warrier, Melissa Samuel, Lee D Spate, Patrick D Allen, Brieanna M Hilkin, Guillermo S Romano Ibarra, Miguel E Ortiz Bezara, Brian J Goodell, Steven E Mather, Linda S Powers, Mallory R Stroik, Nicholas D Gansemer, Camilla E Hippee, Keyan Zarei, J Adam Goeken, Thomas R Businga, Eric A Hoffman, David K Meyerholz, Randall S Prather, David A Stoltz, Michael J Welsh
Published 2020-10-01

S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and LipogenesisSummary

by Linqiang Zhang, Zhiguo Zhang, Chengbin Li, Tingting Zhu, Jing Gao, Hu Zhou, Yingzhuan Zheng, Qing Chang, Mingshan Wang, Jieyu Wu, Liyuan Ran, Yingjie Wu, Huilai Miao, Xiaoju Zou, Bin Liang
Published 2021-01-01

Dendritic cells focus CTL responses toward highly conserved and topologically important HIV-1 epitopes

by Tatiana M. Garcia-Bates, Mariana L. Palma, Renee R. Anderko, Denise C. Hsu, Jintanat Ananworanich, Bette T. Korber, Gaurav D. Gaiha, Nittaya Phanuphak, Rasmi Thomas, Sodsai Tovanabutra, Bruce D. Walker, John W. Mellors, Paolo A. Piazza, Eugene Kroon, Sharon A. Riddler, Nelson L. Michael, Charles R. Rinaldo, Robbie B. Mailliard
Published 2021-01-01

HIGH-FREQUENCY failure of combination antiretroviral therapy in paediatric HIV infection is associated with unmet maternal needs causing maternal NON-ADHERENCE

by Jane R. Millar, Nomonde Bengu, Rowena Fillis, Ken Sprenger, Vuyokazi Ntlantsana, Vinicius A. Vieira, Nisreen Khambati, Moherndran Archary, Maximilian Muenchhoff, Andreas Groll, Nicholas Grayson, John Adamson, Katya Govender, Krista Dong, Photini Kiepiela, Bruce D. Walker, David Bonsall, Thomas Connor, Matthew J. Bull, Nelisiwe Nxele, Julia Roider, Nasreen Ismail, Emily Adland, Maria C. Puertas, Javier Martinez-Picado, Philippa C. Matthews, Thumbi Ndung'u, Philip Goulder
Published 2020-05-01

Loss of hepatic DEPTOR alters the metabolic transition to fasting

by Alexandre Caron, Mathilde Mouchiroud, Nicolas Gautier, Sébastien M. Labbé, Romain Villot, Laurie Turcotte, Blandine Secco, Guillaume Lamoureux, Michael Shum, Yves Gélinas, André Marette, Denis Richard, David M. Sabatini, Mathieu Laplante
Published 2017-05-01

Corrigendum: Candidate Gene Resequencing in a Large Bicuspid Aortic Valve-Associated Thoracic Aortic Aneurysm Cohort: SMAD6 as an Important Contributor

by Elisabeth Gillis, Ajay A. Kumar, Ilse Luyckx, Christoph Preuss, Elyssa Cannaerts, Gerarda van de Beek, Björn Wieschendorf, Björn Wieschendorf, Maaike Alaerts, Nikhita Bolar, Geert Vandeweyer, Josephina Meester, Florian Wünnemann, Russell A. Gould, Rustam Zhurayev, Dmytro Zerbino, Salah A. Mohamed, Seema Mital, Luc Mertens, Hanna M. Björck, Anders Franco-Cereceda, Andrew S. McCallion, Lut Van Laer, Judith M. A. Verhagen, Ingrid M. B. H. van de Laar, Marja W. Wessels, Emmanuel Messas, Guillaume Goudot, Michaela Nemcikova, Alice Krebsova, Marlies Kempers, Simone Salemink, Toon Duijnhouwer, Xavier Jeunemaitre, Juliette Albuisson, Per Eriksson, Gregor Andelfinger, Harry C. Dietz, Harry C. Dietz, Aline Verstraeten, Bart L. Loeys, Bart L. Loeys, Mibava Leducq Consortium
Published 2017-09-01

Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2

by Aram S. Modrek, Danielle Golub, Themasap Khan, Devin Bready, Jod Prado, Christopher Bowman, Jingjing Deng, Guoan Zhang, Pedro P. Rocha, Ramya Raviram, Charalampos Lazaris, James M. Stafford, Gary LeRoy, Michael Kader, Joravar Dhaliwal, N. Sumru Bayin, Joshua D. Frenster, Jonathan Serrano, Luis Chiriboga, Rabaa Baitalmal, Gouri Nanjangud, Andrew S. Chi, John G. Golfinos, Jing Wang, Matthias A. Karajannis, Richard A. Bonneau, Danny Reinberg, Aristotelis Tsirigos, David Zagzag, Matija Snuderl, Jane A. Skok, Thomas A. Neubert, Dimitris G. Placantonakis
Published 2017-10-01

Stabilization of the SARS-CoV-2 Spike Receptor-Binding Domain Using Deep Mutational Scanning and Structure-Based Design

by Daniel Ellis, Daniel Ellis, Daniel Ellis, Natalie Brunette, Natalie Brunette, Katharine H. D. Crawford, Katharine H. D. Crawford, Katharine H. D. Crawford, Alexandra C. Walls, Minh N. Pham, Minh N. Pham, Chengbo Chen, Chengbo Chen, Karla-Luise Herpoldt, Karla-Luise Herpoldt, Brooke Fiala, Brooke Fiala, Michael Murphy, Michael Murphy, Deleah Pettie, Deleah Pettie, John C. Kraft, John C. Kraft, Keara D. Malone, Mary Jane Navarro, Cassandra Ogohara, Cassandra Ogohara, Elizabeth Kepl, Elizabeth Kepl, Rashmi Ravichandran, Rashmi Ravichandran, Claire Sydeman, Claire Sydeman, Maggie Ahlrichs, Maggie Ahlrichs, Max Johnson, Max Johnson, Alyssa Blackstone, Alyssa Blackstone, Lauren Carter, Lauren Carter, Tyler N. Starr, Allison J. Greaney, Allison J. Greaney, Allison J. Greaney, Kelly K. Lee, Kelly K. Lee, David Veesler, Jesse D. Bloom, Jesse D. Bloom, Jesse D. Bloom, Neil P. King, Neil P. King
Published 2021-06-01

Clinical and Molecular Findings in Mendelian Susceptibility to Mycobacterial Diseases: Experience From India

by Prasad D. Taur, Vijaya Gowri, Ambreen Abdulwahab Pandrowala, Vaishnavi V. Iyengar, Akshaya Chougule, Zainab Golwala, Shraddha Chandak, Reepa Agarwal, Purva Keni, Neha Dighe, Minnie Bodhanwala, Shakuntala Prabhu, Biju George, N. A. Fouzia, Eunice Sindhuvi Edison, Arun Kumar Arunachalam, Manisha Rajan Madkaikar, Aparna Dhondi Dalvi, Reetika Malik Yadav, Umair Ahmed Bargir, Priyanka Madhav Kambli, Amit Rawat, Jhumki Das, Vibhu Joshi, Rakesh Kumar Pilania, Ankur Kumar Jindal, Sunil Bhat, Sagar Bhattad, Jeeson Unni, Nita Radhakrishnan, Revathi Raj, Ramya Uppuluri, Shivani Patel, Harsha Prasada Lashkari, Amita Aggarwal, Manas Kalra, Zarir Udwadia, Vibha Sanjay Bafna, Tarun Kanade, Anne Puel, Anne Puel, Anne Puel, Jacinta Bustamante, Jacinta Bustamante, Jacinta Bustamante, Jacinta Bustamante, Jean Laurent Casanova, Jean Laurent Casanova, Jean Laurent Casanova, Jean Laurent Casanova, Mukesh M. Desai
Published 2021-02-01

Large-scale genomic analysis reveals the genetic cost of chicken domestication

by Ming-Shan Wang, Jin-Jin Zhang, Xing Guo, Ming Li, Rachel Meyer, Hidayat Ashari, Zhu-Qing Zheng, Sheng Wang, Min-Sheng Peng, Yu Jiang, Mukesh Thakur, Chatmongkon Suwannapoom, Ali Esmailizadeh, Nalini Yasoda Hirimuthugoda, Moch Syamsul Arifin Zein, Szilvia Kusza, Hamed Kharrati-Koopaee, Lin Zeng, Yun-Mei Wang, Ting-Ting Yin, Min-Min Yang, Ming-Li Li, Xue-Mei Lu, Emiliano Lasagna, Simone Ceccobelli, Humpita Gamaralalage Thilini Nisanka Gunwardana, Thilina Madusanka Senasig, Shao-Hong Feng, Hao Zhang, Abul Kashem Fazlul Haque Bhuiyan, Muhammad Sajjad Khan, Gamamada Liyanage Lalanie Pradeepa Silva, Le Thi Thuy, Okeyo A. Mwai, Mohamed Nawaz Mohamed Ibrahim, Guojie Zhang, Kai-Xing Qu, Olivier Hanotte, Beth Shapiro, Mirte Bosse, Dong-Dong Wu, Jian-Lin Han, Ya-Ping Zhang
Published 2021-06-01

IRF4 haploinsufficiency in a family with Whipple’s disease

by Antoine Guérin, Gaspard Kerner, Nico Marr, Janet G Markle, Florence Fenollar, Natalie Wong, Sabri Boughorbel, Danielle T Avery, Cindy S Ma, Salim Bougarn, Matthieu Bouaziz, Vivien Béziat, Erika Della Mina, Carmen Oleaga-Quintas, Tomi Lazarov, Lisa Worley, Tina Nguyen, Etienne Patin, Caroline Deswarte, Rubén Martinez-Barricarte, Soraya Boucherit, Xavier Ayral, Sophie Edouard, Stéphanie Boisson-Dupuis, Vimel Rattina, Benedetta Bigio, Guillaume Vogt, Frédéric Geissmann, Lluis Quintana-Murci, Damien Chaussabel, Stuart G Tangye, Didier Raoult, Laurent Abel, Jacinta Bustamante, Jean-Laurent Casanova
Published 2018-03-01

A clinical trial of non-invasive imaging with an anti-HIV antibody labelled with copper-64 in people living with HIV and uninfected controls

by James H. McMahon, Jennifer M. Zerbato, Jillian S.Y. Lau, Jaclyn L. Lange, Michael Roche, Carolin Tumpach, Ashanti Dantanarayana, Ajantha Rhodes, Judy Chang, Thomas A. Rasmussen, Charlene A. Mackenzie, Karen Alt, Michelle Hagenauer, Janine Roney, Jessica O‘Bryan, Alexandra Carey, Richard McIntyre, Paul Beech, Graeme J. O'Keefe, Christian W. Wichmann, Fiona E. Scott, Nancy Guo, Sze-Ting Lee, Zhanqi Liu, Marina Caskey, Michel C. Nussenzweig, Paul S. Donnelly, Gary Egan, Christoph E. Hagemeyer, Andrew M. Scott, Sharon R. Lewin
Published 2021-03-01

The genome of the water strider Gerris buenoi reveals expansions of gene repertoires associated with adaptations to life on the water

by David Armisén, Rajendhran Rajakumar, Markus Friedrich, Joshua B. Benoit, Hugh M. Robertson, Kristen A. Panfilio, Seung-Joon Ahn, Monica F. Poelchau, Hsu Chao, Huyen Dinh, Harsha Vardhan Doddapaneni, Shannon Dugan, Richard A. Gibbs, Daniel S. T. Hughes, Yi Han, Sandra L. Lee, Shwetha C. Murali, Donna M. Muzny, Jiaxin Qu, Kim C. Worley, Monica Munoz-Torres, Ehab Abouheif, François Bonneton, Travis Chen, Li-Mei Chiang, Christopher P. Childers, Andrew G. Cridge, Antonin J. J. Crumière, Amelie Decaras, Elise M. Didion, Elizabeth J. Duncan, Elena N. Elpidina, Marie-Julie Favé, Cédric Finet, Chris G. C. Jacobs, Alys M. Cheatle Jarvela, Emily C. Jennings, Jeffery W. Jones, Maryna P. Lesoway, Mackenzie R. Lovegrove, Alexander Martynov, Brenda Oppert, Angelica Lillico-Ouachour, Arjuna Rajakumar, Peter Nagui Refki, Andrew J. Rosendale, Maria Emilia Santos, William Toubiana, Maurijn van der Zee, Iris M. Vargas Jentzsch, Aidamalia Vargas Lowman, Severine Viala, Stephen Richards, Abderrahman Khila
Published 2018-11-01

Candidate Gene Resequencing in a Large Bicuspid Aortic Valve-Associated Thoracic Aortic Aneurysm Cohort: SMAD6 as an Important Contributor

by Elisabeth Gillis, Ajay A. Kumar, Ilse Luyckx, Christoph Preuss, Elyssa Cannaerts, Gerarda van de Beek, Björn Wieschendorf, Björn Wieschendorf, Maaike Alaerts, Nikhita Bolar, Geert Vandeweyer, Josephina Meester, Florian Wünnemann, Russell A. Gould, Rustam Zhurayev, Dmytro Zerbino, Salah A. Mohamed, Seema Mital, Luc Mertens, Hanna M. Björck, Anders Franco-Cereceda, Andrew S. McCallion, Lut Van Laer, Judith M. A. Verhagen, Ingrid M. B. H. van de Laar, Marja W. Wessels, Emmanuel Messas, Guillaume Goudot, Michaela Nemcikova, Alice Krebsova, Marlies Kempers, Simone Salemink, Toon Duijnhouwer, Xavier Jeunemaitre, Juliette Albuisson, Per Eriksson, Gregor Andelfinger, Harry C. Dietz, Harry C. Dietz, Aline Verstraeten, Bart L. Loeys, Bart L. Loeys, Mibava Leducq Consortium
Published 2017-06-01

Caracterização de genes hipotéticos e o papel da enolase da superfície de C. albicans na adesão celular

by Silva, Richard Cardoso da [UNIFESP]
Published 2016

FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices

by Eitan Lerner, Anders Barth, Jelle Hendrix, Benjamin Ambrose, Victoria Birkedal, Scott C Blanchard, Richard Börner, Hoi Sung Chung, Thorben Cordes, Timothy D Craggs, Ashok A Deniz, Jiajie Diao, Jingyi Fei, Ruben L Gonzalez, Irina V Gopich, Taekjip Ha, Christian A Hanke, Gilad Haran, Nikos S Hatzakis, Sungchul Hohng, Seok-Cheol Hong, Thorsten Hugel, Antonino Ingargiola, Chirlmin Joo, Achillefs N Kapanidis, Harold D Kim, Ted Laurence, Nam Ki Lee, Tae-Hee Lee, Edward A Lemke, Emmanuel Margeat, Jens Michaelis, Xavier Michalet, Sua Myong, Daniel Nettels, Thomas-Otavio Peulen, Evelyn Ploetz, Yair Razvag, Nicole C Robb, Benjamin Schuler, Hamid Soleimaninejad, Chun Tang, Reza Vafabakhsh, Don C Lamb, Claus AM Seidel, Shimon Weiss
Published 2021-03-01

Enabling Global Clinical Collaborations on Identifiable Patient Data: The Minerva Initiative

by Christoffer Nellåker, Christoffer Nellåker, Christoffer Nellåker, Fowzan S. Alkuraya, Gareth Baynam, Gareth Baynam, Gareth Baynam, Raphael A. Bernier, Francois P.J. Bernier, Vanessa Boulanger, Michael Brudno, Han G. Brunner, Jill Clayton-Smith, Benjamin Cogné, Hugh J.S. Dawkins, Hugh J.S. Dawkins, Hugh J.S. Dawkins, Bert B.A. deVries, Sofia Douzgou, Tracy Dudding-Byth, Evan E. Eichler, Evan E. Eichler, Michael Ferlaino, Michael Ferlaino, Karen Fieggen, Helen V. Firth, David R. FitzPatrick, Dylan Gration, Tudor Groza, Melissa Haendel, Nina Hallowell, Nina Hallowell, Nina Hallowell, Ada Hamosh, Jayne Hehir-Kwa, Marc-Phillip Hitz, Mark Hughes, Usha Kini, Tjitske Kleefstra, R Frank Kooy, Peter Krawitz, Sébastien Küry, Melissa Lees, Gholson J. Lyon, Stanislas Lyonnet, Julien L. Marcadier, Stephen Meyn, Veronika Moslerová, Juan M. Politei, Cathryn C. Poulton, F Lucy Raymond, Margot R.F. Reijnders, Peter N. Robinson, Corrado Romano, Catherine M. Rose, David C.G. Sainsbury, Lyn Schofield, Vernon R. Sutton, Marek Turnovec, Anke Van Dijck, Hilde Van Esch, Andrew O.M. Wilkie, The Minerva Consortium
Published 2019-07-01

Análise da adaptação dos códons como uma ferramenta para predizer a abundância de uma proteína e sua correlação com o ruído na expressão gênica

by Ferreira, Renata Carmona [UNIFESP]
Published 2015

Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design

by Jo Lynne Rokita, Komal S. Rathi, Maria F. Cardenas, Kristen A. Upton, Joy Jayaseelan, Katherine L. Cross, Jacob Pfeil, Laura E. Egolf, Gregory P. Way, Alvin Farrel, Nathan M. Kendsersky, Khushbu Patel, Krutika S. Gaonkar, Apexa Modi, Esther R. Berko, Gonzalo Lopez, Zalman Vaksman, Chelsea Mayoh, Jonas Nance, Kristyn McCoy, Michelle Haber, Kathryn Evans, Hannah McCalmont, Katerina Bendak, Julia W. Böhm, Glenn M. Marshall, Vanessa Tyrrell, Karthik Kalletla, Frank K. Braun, Lin Qi, Yunchen Du, Huiyuan Zhang, Holly B. Lindsay, Sibo Zhao, Jack Shu, Patricia Baxter, Christopher Morton, Dias Kurmashev, Siyuan Zheng, Yidong Chen, Jay Bowen, Anthony C. Bryan, Kristen M. Leraas, Sara E. Coppens, HarshaVardhan Doddapaneni, Zeineen Momin, Wendong Zhang, Gregory I. Sacks, Lori S. Hart, Kateryna Krytska, Yael P. Mosse, Gregory J. Gatto, Yolanda Sanchez, Casey S. Greene, Sharon J. Diskin, Olena Morozova Vaske, David Haussler, Julie M. Gastier-Foster, E. Anders Kolb, Richard Gorlick, Xiao-Nan Li, C. Patrick Reynolds, Raushan T. Kurmasheva, Peter J. Houghton, Malcolm A. Smith, Richard B. Lock, Pichai Raman, David A. Wheeler, John M. Maris
Published 2019-11-01

Estudo da evolução molecular de sequências de rDNA 18S aplicado à investigação de fatores de patogenicidade do filo Ascomycota

by Padovan, Ana Carolina Barbosa [UNIFESP]
Published 2015