Partial loss of CFIm25 causes learning deficits and aberrant neuronal alternative polyadenylation

by Callison E Alcott, Hari Krishna Yalamanchili, Ping Ji, Meike E van der Heijden, Alexander Saltzman, Nathan Elrod, Ai Lin, Mei Leng, Bhoomi Bhatt, Shuang Hao, Qi Wang, Afaf Saliba, Jianrong Tang, Anna Malovannaya, Eric J Wagner, Zhandong Liu, Huda Y Zoghbi
Published 2020-04-01

Stxbp1/Munc18-1 haploinsufficiency impairs inhibition and mediates key neurological features of STXBP1 encephalopathy

by Wu Chen, Zhao-Lin Cai, Eugene S Chao, Hongmei Chen, Colleen M Longley, Shuang Hao, Hsiao-Tuan Chao, Joo Hyun Kim, Jessica E Messier, Huda Y Zoghbi, Jianrong Tang, John W Swann, Mingshan Xue
Published 2020-02-01

Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis

by Satish K Nandakumar, Sean K McFarland, Laura M Mateyka, Caleb A Lareau, Jacob C Ulirsch, Leif S Ludwig, Gaurav Agarwal, Jesse M Engreitz, Bartlomiej Przychodzen, Marie McConkey, Glenn S Cowley, John G Doench, Jaroslaw P Maciejewski, Benjamin L Ebert, David E Root, Vijay G Sankaran
Published 2019-05-01

Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies

by Mashaal Sohail, Robert M Maier, Andrea Ganna, Alex Bloemendal, Alicia R Martin, Michael C Turchin, Charleston WK Chiang, Joel Hirschhorn, Mark J Daly, Nick Patterson, Benjamin Neale, Iain Mathieson, David Reich, Shamil R Sunyaev
Published 2019-03-01

The MBD7 complex promotes expression of methylated transgenes without significantly altering their methylation status

by Dongming Li, Ana Marie S Palanca, So Youn Won, Lei Gao, Ying Feng, Ajay A Vashisht, Li Liu, Yuanyuan Zhao, Xigang Liu, Xiuyun Wu, Shaofang Li, Brandon Le, Yun Ju Kim, Guodong Yang, Shengben Li, Jinyuan Liu, James A Wohlschlegel, Hongwei Guo, Beixin Mo, Xuemei Chen, Julie A Law
Published 2017-04-01

Human Lentiviral Gene Therapy Restores the Cellular Phenotype of Autosomal Recessive Complete IFN-γR1 Deficiency

by Katharina Hahn, Liart Pollmann, Juliette Nowak, Ariane Hai Ha Nguyen, Kathrin Haake, Anna-Lena Neehus, Syed F. Hassnain Waqas, Frank Pessler, Ulrich Baumann, Miriam Hetzel, Jean-Laurent Casanova, Ansgar Schulz, Jacinta Bustamante, Mania Ackermann, Nico Lachmann
Published 2020-06-01

Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer

by João D. Barros-Silva, Douglas E. Linn, Ivana Steiner, Guoji Guo, Adnan Ali, Hubert Pakula, Garry Ashton, Isabel Peset, Michael Brown, Noel W. Clarke, Roderick T. Bronson, Guo-Cheng Yuan, Stuart H. Orkin, Zhe Li, Esther Baena
Published 2018-12-01

p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas

by Meng-Hsiung Hsieh, Joshua H. Choe, Jashkaran Gadhvi, Yoon Jung Kim, Marcus A. Arguez, Madison Palmer, Haleigh Gerold, Chance Nowak, Hung Do, Simbarashe Mazambani, Jordan K. Knighton, Matthew Cha, Justin Goodwin, Min Kyu Kang, Ji Yun Jeong, Shin Yup Lee, Brandon Faubert, Zhenyu Xuan, E. Dale Abel, Claudio Scafoglio, David B. Shackelford, John D. Minna, Pankaj K. Singh, Vladimir Shulaev, Leonidas Bleris, Kenneth Hoyt, James Kim, Masahiro Inoue, Ralph J. DeBerardinis, Tae Hoon Kim, Jung-whan Kim
Published 2019-08-01

Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood

by Songming Peng, Jesse M. Zaretsky, Alphonsus H.C. Ng, William Chour, Michael T. Bethune, Jongchan Choi, Alice Hsu, Elizabeth Holman, Xiaozhe Ding, Katherine Guo, Jungwoo Kim, Alexander M. Xu, John E. Heath, Won Jun Noh, Jing Zhou, Yapeng Su, Yue Lu, Jami McLaughlin, Donghui Cheng, Owen N. Witte, David Baltimore, Antoni Ribas, James R. Heath
Published 2019-09-01

Single-cell transcriptome identifies FCGR3B upregulated subtype of alveolar macrophages in patients with critical COVID-19

by Nasna Nassir, Richa Tambi, Asma Bankapur, Saba Al Heialy, Noushad Karuvantevida, Hamda Hassan Khansaheb, Binte Zehra, Ghausia Begum, Reem Abdel Hameid, Awab Ahmed, Zulfa Deesi, Abdulmajeed Alkhajeh, K.M. Furkan Uddin, Hosneara Akter, Seyed Ali Safizadeh Shabestari, Omar Almidani, Amirul Islam, Mellissa Gaudet, Richard Kumaran Kandasamy, Tom Loney, Ahmad Abou Tayoun, Norbert Nowotny, Marc Woodbury-Smith, Proton Rahman, Wolfgang M. Kuebler, Mahmood Yaseen Hachim, Jean-Laurent Casanova, Bakhrom K. Berdiev, Alawi Alsheikh-Ali, Mohammed Uddin
Published 2021-09-01

Homologia, paralogia e função da DGF-1, uma família gênica específica de Trypanosoma cruzi

by Kawashita, Silvia Yukie [UNIFESP]
Published 2015

Combining brain perturbation and neuroimaging in non-human primates

by P. Christiaan Klink, Jean-François Aubry, Vincent P. Ferrera, Andrew S. Fox, Sean Froudist-Walsh, Béchir Jarraya, Elisa E. Konofagou, Richard J. Krauzlis, Adam Messinger, Anna S. Mitchell, Michael Ortiz-Rios, Hiroyuki Oya, Angela C. Roberts, Anna Wang Roe, Matthew F.S. Rushworth, Jérôme Sallet, Michael Christoph Schmid, Charles E. Schroeder, Jordy Tasserie, Doris Y. Tsao, Lynn Uhrig, Wim Vanduffel, Melanie Wilke, Igor Kagan, Christopher I. Petkov
Published 2021-07-01

Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens

by George Ueda, Aleksandar Antanasijevic, Jorge A Fallas, William Sheffler, Jeffrey Copps, Daniel Ellis, Geoffrey B Hutchinson, Adam Moyer, Anila Yasmeen, Yaroslav Tsybovsky, Young-Jun Park, Matthew J Bick, Banumathi Sankaran, Rebecca A Gillespie, Philip JM Brouwer, Peter H Zwart, David Veesler, Masaru Kanekiyo, Barney S Graham, Rogier W Sanders, John P Moore, Per Johan Klasse, Andrew B Ward, Neil P King, David Baker
Published 2020-08-01

Recessive Mutations in SYNPO2 as a Candidate of Monogenic Nephrotic Syndrome

by Youying Mao, Ronen Schneider, Peter F.M. van der Ven, Marvin Assent, Keerthika Lohanadan, Verena Klämbt, Florian Buerger, Thomas M. Kitzler, Konstantin Deutsch, Makiko Nakayama, Amar J. Majmundar, Nina Mann, Tobias Hermle, Ana C. Onuchic-Whitford, Wei Zhou, Nandini Nagarajan Margam, Roy Duncan, Jonathan Marquez, Mustafa Khokha, Hanan M. Fathy, Jameela A. Kari, Sherif El Desoky, Loai A. Eid, Hazem Subhi Awad, Muna Al-Saffar, Shrikant Mane, Richard P. Lifton, Dieter O. Fürst, Shirlee Shril, Friedhelm Hildebrandt
Published 2021-02-01

Loss of MeCP2 Function Across Several Neuronal Populations Impairs Breathing Response to Acute Hypoxia

by Christopher S. Ward, Christopher S. Ward, Christopher S. Ward, Teng-Wei Huang, Teng-Wei Huang, Jose A. Herrera, Jose A. Herrera, Rodney C. Samaco, Rodney C. Samaco, Christopher M. McGraw, Christopher M. McGraw, Diana E. Parra, E. Melissa Arvide, Aya Ito-Ishida, Aya Ito-Ishida, Xiangling Meng, Xiangling Meng, Kerstin Ure, Kerstin Ure, Huda Y. Zoghbi, Huda Y. Zoghbi, Huda Y. Zoghbi, Huda Y. Zoghbi, Huda Y. Zoghbi, Huda Y. Zoghbi, Huda Y. Zoghbi, Jeffrey L. Neul, Jeffrey L. Neul, Jeffrey L. Neul, Jeffrey L. Neul, Jeffrey L. Neul, Jeffrey L. Neul
Published 2020-10-01

Differential Effector Engagement by Oncogenic KRAS

by Tina L. Yuan, Arnaud Amzallag, Rachel Bagni, Ming Yi, Shervin Afghani, William Burgan, Nicole Fer, Leslie A. Strathern, Katie Powell, Brian Smith, Andrew M. Waters, David Drubin, Ty Thomson, Rosy Liao, Patricia Greninger, Giovanna T. Stein, Ellen Murchie, Eliane Cortez, Regina K. Egan, Lauren Procter, Matthew Bess, Kwong Tai Cheng, Chih-Shia Lee, Liam Changwoo Lee, Christof Fellmann, Robert Stephens, Ji Luo, Scott W. Lowe, Cyril H. Benes, Frank McCormick
Published 2018-02-01

Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals

by Alexander M. Wolff, Iris D. Young, Raymond G. Sierra, Aaron S. Brewster, Michael W. Martynowycz, Eriko Nango, Michihiro Sugahara, Takanori Nakane, Kazutaka Ito, Andrew Aquila, Asmit Bhowmick, Justin T. Biel, Sergio Carbajo, Aina E. Cohen, Saul Cortez, Ana Gonzalez, Tomoya Hino, Dohyun Im, Jake D. Koralek, Minoru Kubo, Tomas S. Lazarou, Takashi Nomura, Shigeki Owada, Avi J. Samelson, Tomoyuki Tanaka, Rie Tanaka, Erin M. Thompson, Henry van den Bedem, Rahel A. Woldeyes, Fumiaki Yumoto, Wei Zhao, Kensuke Tono, Sebastien Boutet, So Iwata, Tamir Gonen, Nicholas K. Sauter, James S. Fraser, Michael C. Thompson
Published 2020-03-01

Identification of an Endoglin Variant Associated With HCV-Related Liver Fibrosis Progression by Next-Generation Sequencing

by Frédégonde About, Frédégonde About, Stéphanie Bibert, Emmanuelle Jouanguy, Emmanuelle Jouanguy, Bertrand Nalpas, Lazaro Lorenzo, Lazaro Lorenzo, Vimel Rattina, Vimel Rattina, Mohammed Zarhrate, Sylvain Hanein, Sylvain Hanein, Mona Munteanu, Beat Müllhaupt, David Semela, Nasser Semmo, Jean-Laurent Casanova, Jean-Laurent Casanova, Jean-Laurent Casanova, Jean-Laurent Casanova, Jean-Laurent Casanova, Ioannis Theodorou, Philippe Sultanik, Thierry Poynard, Thierry Poynard, Stanislas Pol, Pierre-Yves Bochud, Aurélie Cobat, Aurélie Cobat, Laurent Abel, Laurent Abel, Laurent Abel, The Swiss Hepatitis C Cohort Study Group, The French ANRS HC EP 26 Genoscan Study Group, Francesco Negro, Antoine Hadengue, Laurent Kaiser, Laura Rubbia-Brandt, Darius Moradpour, Cristina Cellerai, Martin Rickenbach, Andreas Cerny, Gladys Martinetti, Jean-François Dufour, Meri Gorgievski, Virginie Masserey Spicher, Markus Heim, Hans Hirsch, Beat Helbling, Stephan Regenass, Raffaele Malinverni, Guenter Dollenmaier, Gieri Cathomas
Published 2019-11-01

Plasma CXCL13 but Not B Cell Frequencies in Acute HIV Infection Predicts Emergence of Cross-Neutralizing Antibodies

by Jenniffer M. Mabuka, Jenniffer M. Mabuka, Jenniffer M. Mabuka, Anne-Sophie Dugast, Daniel M. Muema, Daniel M. Muema, Daniel M. Muema, Tarylee Reddy, Yathisha Ramlakhan, Yathisha Ramlakhan, Zelda Euler, Nasreen Ismail, Amber Moodley, Amber Moodley, Krista L. Dong, Krista L. Dong, Lynn Morris, Lynn Morris, Bruce D. Walker, Bruce D. Walker, Bruce D. Walker, Bruce D. Walker, Galit Alter, Thumbi Ndung’u, Thumbi Ndung’u, Thumbi Ndung’u, Thumbi Ndung’u
Published 2017-09-01

Association of Urinary MyProstateScore, Age, and Prostate Volume in a Longitudinal Cohort of Healthy Men: Long-term Findings from the Olmsted County Study

by Jeffrey J. Tosoian, Rodney L. Dunn, Yashar S. Niknafs, Anjan Saha, Randy A. Vince, Jr, Jennifer L. St. Sauver, Debra J. Jacobson, Michaela E. McGree, Javed Siddiqui, Jack Groskopf, Steven J. Jacobsen, Scott A. Tomlins, Lakshmi P. Kunju, Todd M. Morgan, Simpa S. Salami, John T. Wei, Arul M. Chinnaiyan, Aruna V. Sarma
Published 2021-07-01