Depletion of Hemoglobin Transcripts and Long-Read Sequencing Improves the Transcriptome Annotation of the Polar Bear (Ursus maritimus)

by Ashley Byrne, Ashley Byrne, Megan A. Supple, Roger Volden, Roger Volden, Kristin L. Laidre, Beth Shapiro, Beth Shapiro, Christopher Vollmers, Christopher Vollmers
Published 2019-07-01

Mutations in Cytosine-5 tRNA Methyltransferases Impact Mobile Element Expression and Genome Stability at Specific DNA Repeats

by Bianca Genenncher, Zeljko Durdevic, Katharina Hanna, Daniela Zinkl, Mehrpouya Balaghy Mobin, Nevcin Senturk, Bruno Da Silva, Carine Legrand, Clément Carré, Frank Lyko, Matthias Schaefer
Published 2018-02-01

Mitochondrial and Redox Modifications in Huntington Disease Induced Pluripotent Stem Cells Rescued by CRISPR/Cas9 CAGs Targeting

by Carla Lopes, Carla Lopes, Yang Tang, Yang Tang, Sandra I. Anjo, Sandra I. Anjo, Bruno Manadas, Isabel Onofre, Isabel Onofre, Luís P. de Almeida, Luís P. de Almeida, George Q. Daley, George Q. Daley, George Q. Daley, George Q. Daley, Thorsten M. Schlaeger, Thorsten M. Schlaeger, Ana Cristina Carvalho Rego, Ana Cristina Carvalho Rego
Published 2020-09-01

Cytoplasmic Polyadenylation Element Binding Proteins CPEB1 and CPEB3 Regulate the Translation of FosB and Are Required for Maintaining Addiction-Like Behaviors Induced by Cocaine

by Bettina Drisaldi, Luca Colnaghi, Amir Levine, YanYou Huang, Anna M. Snyder, Daniel J. Metzger, Martin Theis, Denise B. Kandel, Denise B. Kandel, Eric R. Kandel, Eric R. Kandel, Eric R. Kandel, Eric R. Kandel, Luana Fioriti, Luana Fioriti, Luana Fioriti
Published 2020-07-01

ALPK2 Promotes Cardiogenesis in Zebrafish and Human Pluripotent Stem Cells

by Peter Hofsteen, Aaron Mark Robitaille, Nicholas Strash, Nathan Palpant, Randall T. Moon, Lil Pabon, Charles E. Murry
Published 2018-04-01

The Phosphoinositide Kinase PIKfyve Promotes Cathepsin-S-Mediated Major Histocompatibility Complex Class II Antigen Presentation

by Maksim V. Baranov, Frans Bianchi, Anastasiya Schirmacher, Melissa A.C. van Aart, Sjors Maassen, Elke M. Muntjewerff, Ilse Dingjan, Martin ter Beest, Martijn Verdoes, Samantha G.L. Keyser, Carolyn R. Bertozzi, Ulf Diederichsen, Geert van den Bogaart
Published 2019-01-01

Leiomodin-3-deficient mice display nemaline myopathy with fast-myofiber atrophy

by Lei Tian, Sheng Ding, Yun You, Tong-ruei Li, Yan Liu, Xiaohui Wu, Ling Sun, Tian Xu
Published 2015-06-01

SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres

by Bingbing Wan, Jinhu Yin, Kent Horvath, Jaya Sarkar, Yong Chen, Jian Wu, Ke Wan, Jian Lu, Peili Gu, Eun Young Yu, Neal F. Lue, Sandy Chang, Yie Liu, Ming Lei
Published 2013-09-01

A new mouse model to study restoration of interleukin-6 (IL-6) expression in a Cre-dependent manner: microglial IL-6 regulation of experimental autoimmune encephalomyelitis

by Paula Sanchis, Olaya Fernández-Gayol, Gemma Comes, Kevin Aguilar, Anna Escrig, Mercedes Giralt, Richard D. Palmiter, Juan Hidalgo
Published 2020-10-01

Cell-Autonomous Regulation of Astrocyte Activation by the Circadian Clock Protein BMAL1

by Brian V. Lananna, Collin J. Nadarajah, Mariko Izumo, Michelle R. Cedeño, David D. Xiong, Julie Dimitry, Chak Foon Tso, Celia A. McKee, Percy Griffin, Patrick W. Sheehan, Jeffery A. Haspel, Ben A. Barres, Shane A. Liddelow, Joseph S. Takahashi, Ilia N. Karatsoreos, Erik S. Musiek
Published 2018-10-01

The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation

by Di Chen, Wanlu Liu, Jill Zimmerman, William A. Pastor, Rachel Kim, Linzi Hosohama, Jamie Ho, Marianna Aslanyan, Joanna J. Gell, Steven E. Jacobsen, Amander T. Clark
Published 2018-12-01

A Bacterial Pathogen Senses Host Mannose to Coordinate Virulence

by Lifan Wei, Haoxian Qiao, Brandon Sit, Kaiyu Yin, Guanhua Yang, Ruiqing Ma, Jiabao Ma, Chun Yang, Jun Yao, Yue Ma, Jingfan Xiao, Xiaohong Liu, Yuanxing Zhang, Matthew K. Waldor, Qiyao Wang
Published 2019-10-01

Protective Function of Mitogen‐Activated Protein Kinase Phosphatase 5 in Aging‐ and Diet‐Induced Hepatic Steatosis and Steatohepatitis

by Peng Tang, Heng Boon Low, Chin Wen Png, Federico Torta, Jaspal Kaur Kumar, Hwee Ying Lim, Yi Zhou, Henry Yang, Veronique Angeli, Asim Shabbir, E. Shyong Tai, Richard A. Flavell, Chen Dong, Markus R. Wenk, Dan Yock Yang, Yongliang Zhang
Published 2019-06-01

Retinal Cell Type DNA Methylation and Histone Modifications Predict Reprogramming Efficiency and Retinogenesis in 3D Organoid Cultures

by Lu Wang, Daniel Hiler, Beisi Xu, Issam AlDiri, Xiang Chen, Xin Zhou, Lyra Griffiths, Marc Valentine, Abbas Shirinifard, András Sablauer, Suresh Thiagarajan, Marie-Elizabeth Barabas, Jiakun Zhang, Dianna Johnson, Sharon Frase, Michael A. Dyer
Published 2018-03-01

Disseminated Mycobacterium simiae Infection in a Patient with Complete IL-12p40 Deficiency

by Seyed Alireza Mahdaviani, Majid Marjani, Mahnaz Jamee, Armin Khavandegar, Hosseinali Ghaffaripour, Golnaz Eslamian, Mehdi Ghaini, Shabnam Eskandarzadeh, Jean-Laurent Casanova, Jacinta Bustamante, Davood Mansouri, Ali Akbar Velayati
Published 2021-06-01

Maturation of Purkinje cell firing properties relies on neurogenesis of excitatory neurons

by Meike E van der Heijden, Elizabeth P Lackey, Ross Perez, Fatma S Ișleyen, Amanda M Brown, Sarah G Donofrio, Tao Lin, Huda Y Zoghbi, Roy V Sillitoe
Published 2021-09-01

Learning from HIV-1 to predict the immunogenicity of T cell epitopes in SARS-CoV-2

by Ang Gao, Zhilin Chen, Assaf Amitai, Julia Doelger, Vamsee Mallajosyula, Emily Sundquist, Florencia Pereyra Segal, Mary Carrington, Mark M. Davis, Hendrik Streeck, Arup K. Chakraborty, Boris Julg
Published 2021-04-01

Divergent and self-reactive immune responses in the CNS of COVID-19 patients with neurological symptoms

by Eric Song, Christopher M. Bartley, Ryan D. Chow, Thomas T. Ngo, Ruoyi Jiang, Colin R. Zamecnik, Ravi Dandekar, Rita P. Loudermilk, Yile Dai, Feimei Liu, Sara Sunshine, Jamin Liu, Wesley Wu, Isobel A. Hawes, Bonny D. Alvarenga, Trung Huynh, Lindsay McAlpine, Nur-Taz Rahman, Bertie Geng, Jennifer Chiarella, Benjamin Goldman-Israelow, Chantal B.F. Vogels, Nathan D. Grubaugh, Arnau Casanovas-Massana, Brett S. Phinney, Michelle Salemi, Jessa R. Alexander, Juan A. Gallego, Todd Lencz, Hannah Walsh, Anne E. Wapniarski, Subhasis Mohanty, Carolina Lucas, Jon Klein, Tianyang Mao, Jieun Oh, Aaron Ring, Serena Spudich, Albert I. Ko, Steven H. Kleinstein, John Pak, Joseph L. DeRisi, Akiko Iwasaki, Samuel J. Pleasure, Michael R. Wilson, Shelli F. Farhadian
Published 2021-05-01

Neural correlates of ingroup bias for prosociality in rats

by Inbal Ben-Ami Bartal, Jocelyn M Breton, Huanjie Sheng, Kimberly LP Long, Stella Chen, Aline Halliday, Justin W Kenney, Anne L Wheeler, Paul Frankland, Carrie Shilyansky, Karl Deisseroth, Dacher Keltner, Daniela Kaufer
Published 2021-07-01