Of oncogenes and open science: an interview with Harold Varmus

by Harold Varmus
Published 2019-03-01

Progress toward public access to science.

by Harold Varmus
Published 2008-04-01

Activation of PyMT in beta cells induces irreversible hyperplasia, but oncogene-dependent acinar cell carcinomas when activated in pancreatic progenitors.

by Yi-Chieh Nancy Du, David S Klimstra, Harold Varmus
Published 2009-09-01

Assessing tumor progression factors by somatic gene transfer into a mouse model: Bcl-xL promotes islet tumor cell invasion.

by Yi-Chieh Nancy Du, Brian C Lewis, Douglas Hanahan, Harold Varmus
Published 2007-10-01

Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma

by Arun M Unni, William W Lockwood, Kreshnik Zejnullahu, Shih-Queen Lee-Lin, Harold Varmus
Published 2015-06-01

Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells

by Arun M Unni, Bryant Harbourne, Min Hee Oh, Sophia Wild, John R Ferrarone, William W Lockwood, Harold Varmus
Published 2018-11-01

Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival.

by Dennis Liang Fei, Hayley Motowski, Rakesh Chatrikhi, Sameer Prasad, Jovian Yu, Shaojian Gao, Clara L Kielkopf, Robert K Bradley, Harold Varmus
Published 2016-10-01

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain.

by William Pao, Vincent A Miller, Katerina A Politi, Gregory J Riely, Romel Somwar, Maureen F Zakowski, Mark G Kris, Harold Varmus
Published 2005-03-01

Mutational analysis of EGFR and related signaling pathway genes in lung adenocarcinomas identifies a novel somatic kinase domain mutation in FGFR4.

by Jenifer L Marks, Michael D McLellan, Maureen F Zakowski, Alex E Lash, Yumi Kasai, Stephen Broderick, Inderpal S Sarkaria, Duykhanh Pham, Bhuvanesh Singh, Tracie L Miner, Ginger A Fewell, Lucinda L Fulton, Elaine R Mardis, Richard K Wilson, Mark G Kris, Valerie W Rusch, Harold Varmus, William Pao
Published 2007-05-01

Feasibility study of RCAS-TVA transduction system in the model of mouse liver

by Wu Yu-lien, 吳鈺廉

Mistletoe - From mythology to evidence-based medicine

by Manuela Monti
Published 2015-10-01

Generation of transgenic mouse model expressing TV-A receptor in the mammary gland

by Su-mei Tsai, 蔡夙美