Glucagon-like peptide-1 receptor co-agonists for treating metabolic disease

by Laurie L. Baggio, Daniel J. Drucker
Published 2021-04-01

Incretin receptor null mice reveal key role of GLP-1 but not GIP in pancreatic beta cell adaptation to pregnancy.

by R Charlotte Moffett, Srividya Vasu, Bernard Thorens, Daniel J Drucker, Peter R Flatt
Published 2014-01-01

Sitagliptin Accelerates Endothelial Regeneration after Vascular Injury Independent from GLP1 Receptor Signaling

by Friederike Remm, Nicolle Kränkel, Daniela Lener, Daniel J. Drucker, Sieghart Sopper, Christoph Brenner
Published 2018-01-01

Levels of circulating semaglutide determine reductions in HbA1c and body weight in people with type 2 diabetes

by Rune V. Overgaard, Christin L. Hertz, Steen H. Ingwersen, Andrea Navarria, Daniel J. Drucker
Published 2021-09-01

GLP-2 receptor signaling controls circulating bile acid levels but not glucose homeostasis in Gcgr−/− mice and is dispensable for the metabolic benefits ensuing after vertical slee...

by Anita Patel, Bernardo Yusta, Dianne Matthews, Maureen J. Charron, Randy J. Seeley, Daniel J. Drucker
Published 2018-10-01

Lipid-mediated release of GLP-1 by mouse taste buds from circumvallate papillae: putative involvement of GPR120 and impact on taste sensitivity

by Céline Martin, Patricia Passilly-Degrace, Michaël Chevrot, Déborah Ancel, Steven M. Sparks, Daniel J. Drucker, Philippe Besnard
Published 2012-11-01

Oxyntomodulin regulates resetting of the liver circadian clock by food

by Dominic Landgraf, Anthony H Tsang, Alexei Leliavski, Christiane E Koch, Johanna L Barclay, Daniel J Drucker, Henrik Oster
Published 2015-03-01

Intestine-selective reduction of Gcg expression reveals the importance of the distal gut for GLP-1 secretion

by Brandon L. Panaro, Bernardo Yusta, Dianne Matthews, Jacqueline A. Koehler, Youngmi Song, Darleen A. Sandoval, Daniel J. Drucker
Published 2020-07-01

Glucagon-like peptide-2 promotes gallbladder refilling via a TGR5-independent, GLP-2R-dependent pathway

by Bernardo Yusta, Dianne Matthews, Grace B. Flock, John R. Ussher, Brigitte Lavoie, Gary M. Mawe, Daniel J. Drucker
Published 2017-06-01

Enteroendocrine-derived glucagon-like peptide-2 controls intestinal amino acid transport

by Jennifer Lee, Jacqueline Koehler, Bernardo Yusta, Jasmine Bahrami, Dianne Matthews, Mahroukh Rafii, Paul B. Pencharz, Daniel J. Drucker
Published 2017-03-01

Microbially produced glucagon-like peptide 1 improves glucose tolerance in mice

by Tulika Arora, Udo Wegmann, Anup Bobhate, Ying Shiuan Lee, Thomas U. Greiner, Daniel J. Drucker, Arjan Narbad, Fredrik Bäckhed
Published 2016-08-01

Distinct Neural Sites of GLP-1R Expression Mediate Physiological versus Pharmacological Control of Incretin Action

by Elodie M. Varin, Erin E. Mulvihill, Laurie L. Baggio, Jacqueline A. Koehler, Xiemin Cao, Randy J. Seeley, Daniel J. Drucker
Published 2019-06-01

Plasma levels of DPP4 activity and sDPP4 are dissociated from inflammation in mice and humans

by Laurie L. Baggio, Elodie M. Varin, Jacqueline A. Koehler, Xiemin Cao, Yuliya Lokhnygina, Susanna R. Stevens, Rury R. Holman, Daniel J. Drucker
Published 2020-07-01

Hematopoietic cell– versus enterocyte-derived dipeptidyl peptidase-4 differentially regulates triglyceride excursion in mice

by Elodie M. Varin, Antonio A. Hanson, Jacqueline L. Beaudry, My-Anh Nguyen, Xiemin Cao, Laurie L. Baggio, Erin E. Mulvihill, Daniel J. Drucker
Published 2020-08-01

The gut hormone receptor GIPR links energy availability to the control of hematopoiesis

by Gemma Pujadas, Elodie M. Varin, Laurie L. Baggio, Erin E. Mulvihill, K.W.Annie Bang, Jacqueline A. Koehler, Dianne Matthews, Daniel J. Drucker
Published 2020-09-01

TCF7 is not essential for glucose homeostasis in mice

by Kiran Deep Kaur, Chi Kin Wong, Laurie L. Baggio, Jacqueline L. Beaudry, Shai Fuchs, Brandon L. Panaro, Dianne Matthews, Xiemin Cao, Daniel J. Drucker
Published 2021-06-01

GIPR Signaling in Immune Cells Maintains Metabolically Beneficial Type 2 Immune Responses in the White Fat From Obese Mice

by Irina Efimova, Irina Efimova, Inbar Steinberg, Inbar Steinberg, Isabel Zvibel, Anat Neumann, Anat Neumann, Dana Fernanda Mantelmacher, Daniel J. Drucker, Sigal Fishman, Chen Varol, Chen Varol
Published 2021-02-01

Physiological roles of the GIP receptor in murine brown adipose tissue

by Jacqueline L. Beaudry, Kiran D. Kaur, Elodie M. Varin, Laurie L. Baggio, Xiemin Cao, Erin E. Mulvihill, Holly E. Bates, Jonathan E. Campbell, Daniel J. Drucker
Published 2019-10-01

Resveratrol increases glucose induced GLP-1 secretion in mice: a mechanism which contributes to the glycemic control.

by Thi-Mai Anh Dao, Aurélie Waget, Pascale Klopp, Matteo Serino, Christelle Vachoux, Laurent Pechere, Daniel J Drucker, Serge Champion, Sylvain Barthélemy, Yves Barra, Rémy Burcelin, Eric Sérée
Published 2011-01-01

The endogenous preproglucagon system is not essential for gut growth homeostasis in mice

by Pernille Wismann, Pernille Barkholt, Thomas Secher, Niels Vrang, Henrik B. Hansen, Palle Bekker Jeppesen, Laurie L. Baggio, Jacqueline A. Koehler, Daniel J. Drucker, Darleen A. Sandoval, Jacob Jelsing
Published 2017-07-01