B7-H3 suppresses doxorubicin-induced senescence-like growth arrest in colorectal cancer through the AKT/TM4SF1/SIRT1 pathway

by Ruoqin Wang, Linqing Sun, Suhua Xia, Hongya Wu, Yanchao Ma, Shenghua Zhan, Guangbo Zhang, Xueguang Zhang, Tongguo Shi, Weichang Chen
Published 2021-05-01

Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis

by Peina Wang, Yanmei Cui, Qianqian Ren, Bingqi Yan, Yashuo Zhao, Peng Yu, Guofen Gao, Honglian Shi, Shiyang Chang, Yan-Zhong Chang
Published 2021-05-01

Interrogation of gender disparity uncovers androgen receptor as the transcriptional activator for oncogenic miR-125b in gastric cancer

by Ben Liu, Meng Zhou, Xiangchun Li, Xining Zhang, Qinghua Wang, Luyang Liu, Meng Yang, Da Yang, Yan Guo, Qiang Zhang, Hong Zheng, Qiong Wang, Lian Li, Xinlei Chu, Wei Wang, Haixin Li, Fengju Song, Yuan Pan, Wei Zhang, Kexin Chen
Published 2021-05-01

Single-cell analysis reveals urothelial cell heterogeneity and regenerative cues following cyclophosphamide-induced bladder injury

by Xiaomu Cheng, Huadong Lai, Wenqin Luo, Man Zhang, Juju Miao, Weichen Song, Shunpeng Xing, Jia Wang, Wei-Qiang Gao
Published 2021-05-01

ADIPOR1 deficiency-induced suppression of retinal ELOVL2 and docosahexaenoic acid levels during photoreceptor degeneration and visual loss

by Hideto Osada, Eriko Toda, Kohei Homma, Naymel A. Guzman, Norihiro Nagai, Mamoru Ogawa, Kazuno Negishi, Makoto Arita, Kazuo Tsubota, Yoko Ozawa
Published 2021-05-01

LINC-PINT impedes DNA repair and enhances radiotherapeutic response by targeting DNA-PKcs in nasopharyngeal cancer

by You-hong Wang, Zhen Guo, Liang An, Yong Zhou, Heng Xu, Jing Xiong, Zhao-qian Liu, Xiao-ping Chen, Hong-hao Zhou, Xiong Li, Tao Liu, Wei-hua Huang, Wei Zhang
Published 2021-05-01

Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor

by Tatiana Tiago, Barbara Hummel, Federica F. Morelli, Valentina Basile, Jonathan Vinet, Veronica Galli, Laura Mediani, Francesco Antoniani, Silvia Pomella, Matteo Cassandri, Maria Giovanna Garone, Beatrice Silvestri, Marco Cimino, Giovanna Cenacchi, Roberta Costa, Vincent Mouly, Ina Poser, Esti Yeger-Lotem, Alessandro Rosa, Simon Alberti, Rossella Rota, Anat Ben-Zvi, Ritwick Sawarkar, Serena Carra
Published 2021-05-01

Inhibition of the sonic hedgehog pathway activates TGF-β-activated kinase (TAK1) to induce autophagy and suppress apoptosis in thyroid tumor cells

by Sumei Li, Jingxiang Wang, Yurong Lu, Yuqing Zhao, Richard A. Prinz, Xiulong Xu
Published 2021-05-01

Depleting long noncoding RNA HOTAIR attenuates chronic myelocytic leukemia progression by binding to DNA methyltransferase 1 and inhibiting PTEN gene promoter methylation

by Haiping Song, Lijuan Chen, Wei Liu, Xiaoli Xu, Yongming Zhou, Jianhua Zhu, Xuexing Chen, Ziping Li, Hao Zhou
Published 2021-05-01

WNT/β-catenin-suppressed FTO expression increases m6A of c-Myc mRNA to promote tumor cell glycolysis and tumorigenesis

by Xueying Yang, Fei Shao, Dong Guo, Wei Wang, Juhong Wang, Rongxuan Zhu, Yibo Gao, Jie He, Zhimin Lu
Published 2021-05-01

CXCR4 intracellular protein promotes drug resistance and tumorigenic potential by inversely regulating the expression of Death Receptor 5

by Mushtaq A. Nengroo, Shrankhla Maheshwari, Akhilesh Singh, Ayushi Verma, Rakesh K. Arya, Priyank Chaturvedi, Krishan K. Saini, Anup K. Singh, Abhipsa Sinha, Sanjeev Meena, Annapurna Gupta, Anjali Mishra, Jayanta Sarkar, Dipak Datta
Published 2021-05-01

Correction: Long noncoding RNA lncARSR confers resistance to Adriamycin and promotes osteosarcoma progression

by Peng Shen, Yanfeng Cheng
Published 2021-05-01

MTA2 silencing attenuates the metastatic potential of cervical cancer cells by inhibiting AP1-mediated MMP12 expression via the ASK1/MEK3/p38/YB1 axis

by Chia-Liang Lin, Tsung-Ho Ying, Shun-Fa Yang, Hui-Ling Chiou, Yong-Syuan Chen, Shao-Hsuan Kao, Yi-Hsien Hsieh
Published 2021-05-01

Interaction of calcium binding protein S100A16 with myosin-9 promotes cytoskeleton reorganization in renal tubulointerstitial fibrosis

by Hui Sun, Anran Zhao, Min Li, Hao Dong, Yifei Sun, Xue Zhang, Qian Zhu, Ashfaq-Ahmad-Shah Bukhari, Changchun Cao, Dongming Su, Yun Liu, Xiubin Liang
Published 2020-02-01

Circular RNA circRNF20 promotes breast cancer tumorigenesis and Warburg effect through miR-487a/HIF-1α/HK2

by Lili Cao, Min Wang, Yujin Dong, Bo Xu, Ju Chen, Yu Ding, Shusheng Qiu, Liang Li, Elena Karamfilova Zaharieva, Xinwen Zhou, Yanbin Xu
Published 2020-02-01

Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure

by Naoya Yamada, Tadayoshi Karasawa, Hiroaki Kimura, Sachiko Watanabe, Takanori Komada, Ryo Kamata, Ariunaa Sampilvanjil, Junya Ito, Kiyotaka Nakagawa, Hiroshi Kuwata, Shuntaro Hara, Koichi Mizuta, Yasunaru Sakuma, Naohiro Sata, Masafumi Takahashi
Published 2020-02-01

Suppressing STAT5 signaling affects osteosarcoma growth and stemness

by Dharmalingam Subramaniam, Pablo Angulo, Sivapriya Ponnurangam, Prasad Dandawate, Prabhu Ramamoorthy, Pugazhendhi Srinivasan, Tomoo Iwakuma, Scott J. Weir, Katherine Chastain, Shrikant Anant
Published 2020-02-01

Chromatin accessibility is associated with the changed expression of miRNAs that target members of the Hippo pathway during myoblast differentiation

by Huanhuan Zhou, Yue Xiang, Mingyang Hu, Yueyuan Xu, Ye Hou, Xiaolong Qi, Liangliang Fu, Yu Luan, Zhangxu Wang, Xinyun Li, Yunxia Zhao, Shuhong Zhao
Published 2020-02-01

EMT transcription factor ZEB1 alters the epigenetic landscape of colorectal cancer cells

by Pablo Lindner, Sushmita Paul, Markus Eckstein, Chuanpit Hampel, Julienne K. Muenzner, Katharina Erlenbach-Wuensch, Husayn P. Ahmed, Vijayalakshmi Mahadevan, Thomas Brabletz, Arndt Hartmann, Julio Vera, Regine Schneider-Stock
Published 2020-02-01

Cell death in head and neck cancer pathogenesis and treatment

by Martina Raudenská, Jan Balvan, Michal Masařík
Published 2021-02-01