ABBV-176, a PRLR antibody drug conjugate with a potent DNA-damaging PBD cytotoxin and enhanced activity with PARP inhibition

by Mark G. Anderson, Qian Zhang, Luis E. Rodriguez, Claudie M. Hecquet, Cherrie K. Donawho, Peter J. Ansell, Edward B. Reilly
Published 2021-06-01

Inhibition of STAT3 enhances sensitivity to tamoxifen in tamoxifen-resistant breast cancer cells

by Seo Yun Moon, Heejin Lee, Seoree Kim, Ji Hyung Hong, Sang Hoon Chun, Hee Yeon Lee, Keunsoo Kang, Ho Shik Kim, Hye Sung Won, Yoon Ho Ko
Published 2021-08-01

A novel survival model based on a Ferroptosis-related gene signature for predicting overall survival in bladder cancer

by Yingchun Liang, Fangdie Ye, Chenyang Xu, Lujia Zou, Yun Hu, Jimeng Hu, Haowen Jiang
Published 2021-08-01

Pre-existing interstitial lung disease is associated with onset of nivolumab-induced pneumonitis in patients with solid tumors: a retrospective analysis

by Teppei Yamaguchi, Junichi Shimizu, Takaaki Hasegawa, Yoshitsugu Horio, Yoshitaka Inaba, Nobuhiro Hanai, Kei Muro, Toyoaki Hida
Published 2021-08-01

Optimizing oropharyngeal cancer management by using proton beam therapy: trends of cost-effectiveness

by Guo Li, Yun-Fei Xia, Yi-Xiang Huang, Deniz Okat, Bo Qiu, Jerome Doyen, Pierre-Yves Bondiau, Karen Benezery, Jin Gao, Chao-Nan Qian
Published 2021-08-01

The CRCbiome study: a large prospective cohort study examining the role of lifestyle and the gut microbiome in colorectal cancer screening participants

by Ane Sørlie Kværner, Einar Birkeland, Cecilie Bucher-Johannessen, Elina Vinberg, Jan Inge Nordby, Harri Kangas, Vahid Bemanian, Pekka Ellonen, Edoardo Botteri, Erik Natvig, Torbjørn Rognes, Eivind Hovig, Robert Lyle, Ole Herman Ambur, Willem M. de Vos, Scott Bultman, Anette Hjartåker, Rikard Landberg, Mingyang Song, Hege Salvesen Blix, Giske Ursin, Kristin Ranheim Randel, Thomas de Lange, Geir Hoff, Øyvind Holme, Paula Berstad, Trine B. Rounge
Published 2021-08-01

Gene-associated methylation status of ST14 as a predictor of survival and hormone receptor positivity in breast Cancer

by Yang-Hong Dai, Ying-Fu Wang, Po-Chien Shen, Cheng-Hsiang Lo, Jen-Fu Yang, Chun-Shu Lin, Hsing-Lung Chao, Wen-Yen Huang
Published 2021-08-01

AGITG MASTERPLAN: a randomised phase II study of modified FOLFIRINOX alone or in combination with stereotactic body radiotherapy for patients with high-risk and locally advanced pa...

by Andrew Oar, Mark Lee, Hien Le, Kate Wilson, Chris Aiken, Lorraine Chantrill, John Simes, Nam Nguyen, Andrew Barbour, Jaswinder Samra, Katrin M. Sjoquist, Alisha Moore, David Espinoza, Val Gebski, Sonia Yip, Julie Chu, Andrew Kneebone, David Goldstein
Published 2021-08-01

Regional differences in cervical cancer incidence and associated risk behaviors among Norwegian women: a population-based study

by Bo T. Hansen, Suzanne Campbell, Mari Nygård
Published 2021-08-01

Predicting disease progression in advanced non-small cell lung cancer with circulating neutrophil-derived and platelet-derived microparticles

by Tingting Liu, Jiang Wang, Tao Li, Pengfei Cui, Baicun Hou, Chunxiao Zhuang, Ge Wei, Sujie Zhang, Hongxia Li, Yi Hu
Published 2021-08-01

Possible role of HPV/EBV coinfection in anoikis resistance and development in prostate cancer

by Javid Sadri Nahand, Khadijeh Khanaliha, Hamed Mirzaei, Mohsen Moghoofei, Hossein Bannazadeh Baghi, Maryam Esghaei, Ali Reza Khatami, Maryam Fatemipour, Farah Bokharaei-Salim
Published 2021-08-01

Influence of Epstein–Barr virus and human papillomavirus infection on macrophage migration inhibitory factor and macrophage polarization in nasopharyngeal carcinoma

by Guofei Feng, Yifei Xu, Ning Ma, Kaoru Midorikawa, Shinji Oikawa, Hatasu Kobayashi, Satoshi Nakamura, Hajime Ishinaga, Zhe Zhang, Guangwu Huang, Kazuhiko Takeuchi, Mariko Murata
Published 2021-08-01

Bioinformatics analysis of the transcriptional expression of minichromosome maintenance proteins as potential indicators of survival in patients with cervical cancer

by Baojie Wu, Shuyi Xi
Published 2021-08-01

Development and validation of genomic predictors of radiation sensitivity using preclinical data

by Venkata S. K. Manem
Published 2021-08-01

Identification of PLA2G7 as a novel biomarker of diffuse large B cell lymphoma

by Weili Zheng, Qiaochu Lin, Mohammed Awal Issah, Ziyuan Liao, Jianzhen Shen
Published 2021-08-01

Multiple myeloma in Armenia during the period 2006–2018: facts and discussion

by Narine Ghazaryan, Samvel Danelyan, Samvel Bardakhchyan, Anahit Saharyan, Lusine Sahakyan
Published 2021-08-01

A novel treatment strategy for lapatinib resistance in a subset of HER2-amplified gastric cancer

by Gang Ning, Qihui Zhu, Wonyoung Kang, Hamin Lee, Leigh Maher, Yun-Suhk Suh, Michael Michaud, Mayerlin Silva, Jee Young Kwon, Chengsheng Zhang, Charles Lee
Published 2021-08-01

Personal innovative approach in radiation therapy of lung cancer- functional lung avoidance SPECT-guided (ASPECT) radiation therapy: a study protocol for phase II randomised double...

by Azza Ahmed Khalil, Eric Hau, Val Gebski, Cai Grau, Harriet Gee, Tine Bisballe Nyeng, Katrina West, Stine Kramer, David Farlow, Marianne Knap, Ditte Sloth Møller, Lone Hoffmann, Katherina P. Farr
Published 2021-08-01

The role of the bacterial microbiome in the treatment of cancer

by Zi-Kun Yu, Rui-Ling Xie, Rui You, You-Ping Liu, Xu-Yin Chen, Ming-Yuan Chen, Pei-Yu Huang
Published 2021-08-01

MONARCC: a randomised phase II study of panitumumab monotherapy and panitumumab plus 5-fluorouracil as first-line therapy for RAS and BRAF wildtype metastatic colorectal cancer: a...

by Ho Wai Derrick Siu, Niall Tebbutt, Lorraine Chantrill, Chris Karapetis, Christopher Steer, Kate Wilson, David Espinoza, Lisa Bailey, Sonia Yip, Jeff Cuff, Nick Pavlakis, Subotheni Thavaneswaran, Karen Briscoe, Ratnesh Srivastav, Jennifer Shannon, Eva Segelov, Jeannie Tie, Susan Caird, Alessandra Francesconi, Timothy Price, Melanie Wuttke, Rahul Ladwa, Katrin Sjoquist, Matthew Burge
Published 2021-08-01