protein function Article 73 controlled study 63 human 61 nonhuman 50 Humans 44 protein expression 40 metabolism 39 male 37 unclassified drug 35 genetics 33 female 31 adult 30 animal experiment 25 Animals 24 animal 22 pathology 22 human cell 21 human tissue 21 mouse 21 Male 20 Western blotting 20 animal tissue 19 animal cell 18 animal model 18 gene expression 18 signal transduction 18 upregulation 18 Female 16 cell proliferation 16