Article 1 PAC1R 1 addiction 1 adeno associated virus vector 1 alcohol use disorder (AUD) 1 alcoholism 1 animal experiment 1 animal model 1 animal tissue 1 brain tissue 1 compulsive 1 controlled study 1 ethanol 1 gene silencing 1 genetic predisposition 1 hypophysis adenylate cyclase activating polypeptide receptor 1 1 immunohistochemistry 1 male 1 motivation 1 neuropeptide 1 nonhuman 1 nucleus accumbens 1 pituitary adenylate cyclase activating polypeptide (PACAP) protein targeting 1 rat 1 reinforcement (psychology) 1 self-administration 1 staining 1