1,3 butadiene 1 Article 1 Methylosinus trichosporium 1 OB3b 1 X ray crystallography 1 active sites 1 algorithm 1 amino acid sequence 1 binding affinity 1 binding site 1 catalysis 1 crystal structure 1 docking 1 ethylbenzene 1 hybridization 1 hydrogen bond 1 hydrophobicity 1 methane 1 methanotroph 1 methanotrophs methylotroph 1 molecular docking 1 monomer 1 mutagenesis 1 mutation 1 oxidation 1 pMMO 1 phylogenetic tree 1 protein interaction 1 protein stability 1