matrix metalloproteinase human 12 Humans 11 metabolism 8 Matrix Metalloproteinases 6 controlled study 6 Article 5 genetics 4 human cell 4 nonhuman 4 unclassified drug 4 Collagen 3 MMPs 3 Western blotting 3 animal cell 3 cell viability 3 chemistry 3 down regulation 3 drug effect 3 gelatinase B 3 gene expression 3 neutrophil collagenase 3 signal transduction 3 tissue inhibitor of metalloproteinase 1 3 upregulation 3 Case-Control Studies 2 Chronic Periodontitis 2 Dentin 2 Diabetes Mellitus, Type 2 2 IL10 gene 2