interleukin 6 human 76 Article 72 Humans 60 controlled study 58 tumor necrosis factor 55 metabolism 46 male 41 female 40 nonhuman 40 adult 34 interleukin 1beta 33 Interleukin-6 31 Animals 30 cytokine 30 inflammation 30 Female 28 animal 28 animal experiment 28 Male 27 unclassified drug 27 protein expression 25 Cytokines 24 animal model 23 blood 23 major clinical study 23 middle aged 23 mouse 23 Middle Aged 20 aged 20