inflammasome Inflammasomes 8 cryopyrin 7 Animals 6 NLR Family, Pyrin Domain-Containing 3 Protein 6 animal 6 metabolism 5 Caspase 1 4 Humans 4 Mice 4 human 4 inflammation 4 interleukin 1beta converting enzyme 4 mouse 4 Apoptosis 3 C57BL mouse 3 Mice, Inbred C57BL 3 Signal Transduction 3 apoptosis 3 genetics 3 interleukin 1beta 3 macrophage 3 signal transduction 3 tumor necrosis factor 3 Cell Death 2 Immunity, Innate 2 Inflammation 2 Interleukin-1beta 2 Macrophages 2 Male 2