gene identification controlled study 36 Article 35 human 28 genetics 25 Humans 23 male 20 nonhuman 20 female 18 Female 16 Male 16 adult 16 gene expression 13 unclassified drug 13 gene 12 gene function 11 clinical article 10 genetic association 10 Middle Aged 9 genetic variability 9 genotype 9 major clinical study 9 middle aged 9 phenotype 9 procedures 9 down regulation 8 gene expression regulation 8 pathology 8 Animals 7 RNA sequencing 7