Genotype 2 Humans 2 article 2 denaturing high performance liquid chromatography genetic polymorphism 2 genetic variability 2 genotype 2 human 2 5-fluorouracil 1 Antimetabolites, Antineoplastic 1 Aryl Hydrocarbon Hydroxylases 1 CYP2C8 1 Chromatography, High Pressure Liquid 1 Colorectal Neoplasms 1 Cytochrome P-450 Enzyme System 1 DNA Mutational Analysis 1 Dihydrouracil Dehydrogenase (NADP) 1 Drug-Related Side Effects and Adverse Reactions 1 Fluorouracil 1 Gene Frequency 1 Homozygote 1 Hypertension 1 Malaysia 1 Mutation 1 Polymorphism, Genetic 1 Polymorphism, Single Nucleotide 1 adult 1 adverse effect 1 aged 1 amino acid substitution 1