Antiviral agents 1 Article 1 COVID-19 1 Genetic engineering 1 Genetic selection system 1 MazF toxin 1 SARS-CoV-2 1 Saccharomyces cerevisiae 1 Severe acute respiratory syndrome coronavirus 2 1 Small molecules 1 amino acid 1 amino acid sequence 1 anti-SARS-CoV-2 agent 1 boceprevir 1 cell survival 1 codon 1 concentration (parameter) 1 controlled study 1 coronavirus 3C protease 1 coronavirus proteinase inhibitor drug design 1 drug screening 1 efonidipine 1 fungal strain 1 fusion protein 1 gc 376 1 genetic background 1 genetic engineering 1 genetic selection 1 genetic strain 1