Animals 1 Autophagy 1 CRISPR-CAS9 system 1 CRISPR/Cas9 1 Gene Expression Regulation 1 HeLa Cells 1 HeLa cell line 1 Humans 1 Lysosomes 1 Mice 1 Transcription Factors 1 Western blotting 1 ZKSCAN3 ZKSCAN3 protein, human 1 ZKSCAN3 protein, mouse 1 animal 1 article 1 attention 1 autophagy 1 autophagy (cellular) 1 biogenesis 1 cancer cell 1 cancer growth 1 controlled study 1 fluorescence quantitative polymerase chain reaction 1 gene deletion 1 gene expression regulation 1 genetic transcription 1 genetics 1 human 1