Closed-form expression 1 Correlated tests 1 Correlation matrix 1 Diverse properties 1 Error analysis 1 FWER 1 Genetic Markers 1 MWAS 1 MWSL 1 Metabolism 1 Metabolome 1 Metabolomics 1 Models, Biological 1 Multiple testing 1 Normal distribution 1 Parametric simulations 1 Permutation 1 Permutation procedures Significance levels 1 Spectral decomposition 1 Statistical Distributions 1 Synthetic and real data 1 article 1 biological model 1 decomposition 1 family-wise error rate 1 genetic marker 1 genetics 1 human 1 metabolome 1