Algorithms 1 Background signals 1 Bias 1 ChIP-seq 1 Chromatin Immunoprecipitation 1 Chromatin Immunoprecipitation Sequencing 1 Chromatin immunoprecipitation 1 Controls 1 DNA sequence 1 High-Throughput Nucleotide Sequencing 1 High-throughput sequencing 1 Histone modification 1 Least squares regression 1 Noise distribution Reproducibilities 1 Reproducibility of Results 1 Scientific community 1 Sequence Analysis, DNA 1 algorithm 1 article 1 chromatin immunoprecipitation 1 chromatin immunoprecipitation sequencing 1 controlled study 1 high throughput sequencing 1 histone modification 1 least square analysis 1 noise 1 reliability 1 reproducibility 1