AMYLOID PRECURSOR PROTEIN 1 Alzheimer's disease 1 BRAIN-BARRIER PERMEABILITY 1 CEREBRAL-BLOOD-FLOW 1 Centella asiatica 1 ELEMENT-BINDING PROTEIN 1 HEME OXYGENASE-1 EXPRESSION INFLAMMATORY RESPONSE 1 MOUSE MODEL 1 NF-KAPPA-B 1 NF-kappa beta 1 Nrf2 1 OXIDATIVE STRESS 1 UP-REGULATION 1 hypoxia 1 neurodegenerative disease 1 neuroinflammation 1 neuroprotective 1