2 hydroxypropyl beta cyclodextrin 1 Animal Experimentation 1 Animal Welfare Animals 1 Article 1 Rats 1 Toxicity Tests 1 acetic acid 1 anesthesia 1 animal 1 animal experiment 1 animal model 1 animal use 1 animal welfare 1 antineoplastic agent 1 autopsy 1 blood sampling 1 body weight 1 body weight change 1 body weight loss 1 bone marrow 1 buffer 1 carotid artery 1 cecum 1 centrifugation 1 colon 1 controlled study 1 distress syndrome 1 drinking water 1 drug toxicity 1