4-Hydroxyphenylacetic acid 1 ATP engineering Biochemistry 1 Bioproducts 1 CRISPRi 1 Cofactor engineering 1 Encoding (symbols) 1 Encoding genes 1 Enzymes 1 Escherichia coli 1 Fed-batch fermentation 1 Genes 1 High-level production 1 Microbial biotechnology 1 NADPH engineering 1 Novel strategies 1 Palindromic 1 Quorum-sensing 1 Signal encoding 1 biotechnology 1 carboxylic acid 1 coliform bacterium 1 enzyme 1 genetic engineering 1