Dysregulation of Glucose Homeostasis Following Chronic Exogenous Administration of Leptin in Healthy Sprague-Dawley Rats

Dysregulation of Glucose Homeostasis Following Chronic Exogenous Administration of Leptin in Healthy Sprague-Dawley Rats

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Introduction: Impaired glucose utilization is seen in chronic hyper-leptinaemia associated conditions such as obesity and type 2 diabetes mellitus. It is unclear if this impaired glucose utilization is due to the effect of persistent hyperleptinaemia on insulin secretion from the beta cells of pancr...

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Bibliographic Details
Main Authors: Caszo, B (Author), Gnanou, J (Author), Ibrahim, E (Author), Singh, H (Author), Wjidan, K (Author)
Format: Article
Language:English
Published: 2015
Subjects:
Glucose homeostasis
GLUT 4
Hyperinsulinaemia
Hyperleptinaemia
Insulin receptor
Online Access:View Fulltext in Publisher
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245 1 0 |a Dysregulation of Glucose Homeostasis Following Chronic Exogenous Administration of Leptin in Healthy Sprague-Dawley Rats 
260 0 |c 2015 
856 |z View Fulltext in Publisher  |u https://doi.org/10.7860/JCDR/2015/15594.7003 
520 3 |a Introduction: Impaired glucose utilization is seen in chronic hyper-leptinaemia associated conditions such as obesity and type 2 diabetes mellitus. It is unclear if this impaired glucose utilization is due to the effect of persistent hyperleptinaemia on insulin secretion from the beta cells of pancreas. 
650 0 4 |a Glucose homeostasis 
650 0 4 |a GLUT 4 
650 0 4 |a Hyperinsulinaemia 
650 0 4 |a Hyperleptinaemia 
650 0 4 |a Insulin receptor 
700 1 0 |a Caszo, B  |e author 
700 1 0 |a Gnanou, J  |e author 
700 1 0 |a Ibrahim, E  |e author 
700 1 0 |a Singh, H  |e author 
700 1 0 |a Wjidan, K  |e author 
773 |t JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH  |g 9 12, OF06-OF09 

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