Chemical characterization of the photodegradation products of midazolam complexes with randomly methylated-beta-cyclodextrin by HPLC and LC-MS/MS

Midazolam, a potent anxiolytic drug with sedative properties, is susceptible to degradation by both light and hydrolysis in aqueous solution. When formulated as an intranasal product, it was found to be effective in achieving seizure control in epileptic patients. In order to deliver an adequate the...

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Bibliographic Details
Main Authors: Agatonovic-Kustrin, S (Author), Brown, ME (Author), Glass, BD (Author), Lebete, M (Author), Morton, DW (Author)
Format: Article
Language:English
Published: 2016
Subjects:
Online Access:View Fulltext in Publisher

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