Systematic Pharmacogenomics Analysis of a Malay Whole Genome: Proof of Concept for Personalized Medicine
Background: With a higher throughput and lower cost in sequencing, second generation sequencing technology has immense potential for translation into clinical practice and in the realization of pharmacogenomics based patient care. The systematic analysis of whole genome sequences to assess patient t...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Online Access: | View Fulltext in Publisher |
| LEADER | 01479nam a2200325Ia 4500 | ||
|---|---|---|---|
| 001 | 10.1371-journal.pone.0071554 | ||
| 008 | 220127s2013 CNT 000 0 und d | ||
| 020 | |a 1932-6203 | ||
| 245 | 1 | 0 | |a Systematic Pharmacogenomics Analysis of a Malay Whole Genome: Proof of Concept for Personalized Medicine |
| 490 | 1 | 0 | |t PLOS ONE |
| 856 | |z View Fulltext in Publisher |u https://doi.org/10.1371/journal.pone.0071554 | ||
| 520 | 3 | |a Background: With a higher throughput and lower cost in sequencing, second generation sequencing technology has immense potential for translation into clinical practice and in the realization of pharmacogenomics based patient care. The systematic analysis of whole genome sequences to assess patient to patient variability in pharmacokinetics and pharmacodynamics responses towards drugs would be the next step in future medicine in line with the vision of personalizing medicine. | |
| 700 | 1 | 0 | |a Adam, A |e author |
| 700 | 1 | 0 | |a Ahmed, AZ |e author |
| 700 | 1 | 0 | |a Hamzah, AS |e author |
| 700 | 1 | 0 | |a Hatta, FHM |e author |
| 700 | 1 | 0 | |a Hoh, BP |e author |
| 700 | 1 | 0 | |a Ismail, MI |e author |
| 700 | 1 | 0 | |a Ismet, RI |e author |
| 700 | 1 | 0 | |a Janor, RM |e author |
| 700 | 1 | 0 | |a Joshi, K |e author |
| 700 | 1 | 0 | |a Lee, LS |e author |
| 700 | 1 | 0 | |a Pasha, A |e author |
| 700 | 1 | 0 | |a Patowary, A |e author |
| 700 | 1 | 0 | |a Salleh, MZ |e author |
| 700 | 1 | 0 | |a Scaria, V |e author |
| 700 | 1 | 0 | |a Sivasubbu, S |e author |
| 700 | 1 | 0 | |a Teh, LK |e author |
| 700 | 1 | 0 | |a Yusoff, K |e author |
| 773 | 1 | 0 | |t PLOS ONE |