Therapeutic Activity of Crude Ethanolic Extract of Artemisia herba alba Against Trypanosoma evansi in Rabbits

The present work was conducted to evaluate the antitrypanosomal efficacy of crude ethanolic extract (CEE) of the aerial parts of Artemisia herba alba against Trypanosoma evansi infection in an animal model. The results indicated low levels of parasitaemia in rabbits administered with crude ethanolic...

Full description

Bibliographic Details
Main Authors: Abu Hasan, ZA (Author), Awad, FM (Author), Ibrahim, N (Author), Osman, AY (Author)
Format: Article
Language:English
Online Access:View Fulltext in Publisher
LEADER 01415nam a2200157Ia 4500
001 10.1063-1.4858650
008 220127s2013 CNT 000 0 und d
020 |a 0094-243X 
020 |a 978-0-7354-1199-9 
245 1 0 |a Therapeutic Activity of Crude Ethanolic Extract of Artemisia herba alba Against Trypanosoma evansi in Rabbits 
856 |z View Fulltext in Publisher  |u https://doi.org/10.1063/1.4858650 
520 3 |a The present work was conducted to evaluate the antitrypanosomal efficacy of crude ethanolic extract (CEE) of the aerial parts of Artemisia herba alba against Trypanosoma evansi infection in an animal model. The results indicated low levels of parasitaemia in rabbits administered with crude ethanolic extract (CEE) compared to those from the negative control group. Similarly, there was also haematologically significant difference (p<0.05) where low mean levels of packed cell volume (PCV) was observed in Groups 1-4 respectively. In contrast, there was no statistically significant difference in almost all investigated parameters between positive control and treatment groups of animals. In conclusion, both CEE of A. herba-alba and Berenil (R) showed relatively a parasitaemia and normal haematological values in infected rabbits, thereby confirming their antiparasitic properties. 
700 1 0 |a Abu Hasan, ZA  |e author 
700 1 0 |a Awad, FM  |e author 
700 1 0 |a Ibrahim, N  |e author 
700 1 0 |a Osman, AY  |e author