Bile acids and their respective conjugates elicit different responses in neonatal cardiomyocytes: role of Gi protein, muscarinic receptors and TGR5

Bile acids and their respective conjugates elicit different responses in neonatal cardiomyocytes: role of Gi protein, muscarinic receptors and TGR5

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Bile acids are recognised as bioactive signalling molecules. While they are known to influence arrhythmia susceptibility in cholestasis, there is limited knowledge about the underlying mechanisms. To delineate mechanisms underlying fetal heart rhythm disturbances in cholestatic pregnancy, we used FR...

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Bibliographic Details
Main Authors: Arunthavarajah, D (Author), Diakonov, I (Author), Goodwin, M (Author), Gorelik, J (Author), Ibrahim, E (Author), McIlvride, S (Author), Nikolova, V (Author), Swift, T (Author), Williamson, C (Author)
Format: Article
Language:English
Published: 2018
Subjects:
DEXAMETHASONE
HEART
INTRAHEPATIC CHOLESTASIS
IN-VITRO
OBSTETRIC CHOLESTASIS
PERMEABILITY TRANSITION
PREGNANCY
RAT CARDIOMYOCYTES
TAUROCHOLATE
URSODEOXYCHOLIC ACID
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